Angela M. Crawley

Dr. Angela M. Crawley is a Senior Scientist at the Ottawa Hospital Research Institute (Chronic Disease Program) and an Associate Professor in the Department of Biochemistry, Microbiology and Immunology at the University of Ottawa. She also holds an Adjunct Professor appointment at Carleton University (Department of Biology). Her research focuses on:

• CD8 T-cell dysfunction in chronic viral infections
• Immune restoration in cirrhosis
• Macrophage-Kupffer cell interactions
• Translational immunology approaches

Dr. Crawley's research combines human immunology and animal models to explore chronic hepatitis C virus infection and non-alcoholic fatty liver disease. Her work has been funded by major grants from the Canadian Institutes of Health Research and Natural Sciences and Engineering Research Council. The laboratory maintains a clinical biobank and collaborates with both basic science and clinical research teams. Key publication trends indicate expertise in:

• Viral immunopathogenesis
• T-cell signaling mechanisms
• Immune subset differentiation
• Cytokine receptor dynamics
• Antiviral therapy limitations
• Translational disease modeling