Andrew McMichael

Andrew McMichael is a Professor of Molecular Medicine at the Nuffield Department of Medicine, University of Oxford. His research focuses on CD8 T cell immune responses and their interactions with HLA molecules, particularly non-classical HLA molecules like HLA-E. He has made significant contributions to understanding T cell epitopes in HIV-1 and SARS-CoV-2, immune escape mechanisms, and vaccine development.

• Key research areas: Immunology, Virology, HLA-E, HIV Vaccines
• Collaborations: Louis Picker (OHSU) on CMV-vectored SIV vaccines

His work on HLA-E restricted T cells explores their potential for universal immunotherapies due to HLA-E's limited polymorphism. Structural studies (e.g., SAXS analysis) and in vitro priming techniques are central to his research.