Andrew L. Lee

Andrew L. Lee is a Professor in the Division of Chemical Biology and Medicinal Chemistry at the University of North Carolina at Chapel Hill School of Medicine and a member of the UNC Lineberger Comprehensive Cancer Center.

Education

• PhD

Research Interests

Dr. Lee's research centers on atomic-resolution characterization of protein conformational changes fundamental to biological processes. He employs heteronuclear NMR spectroscopy as a primary tool to investigate protein dynamics, allosteric mechanisms, and interactions with ligands, other proteins, and small-molecule drugs. His work emphasizes the role of structural flexibility in protein function, with implications for understanding disease mechanisms and therapeutic development.

Scientific Awards

• Junior Faculty IBM Fund Award (2006)
• American Association of Colleges of Pharmacy (AACP) New Investigators Program (NIP) Award for Pharmacy Faculty at UNC-Chapel Hill (2001-2002)

While the provided text does not specify graduate students advised or grant funding details, Dr. Lee maintains an active research program focused on protein dynamics. His laboratory develops and applies advanced NMR methodologies to address fundamental questions in structural biology and cancer research.

He leads a research group utilizing NMR spectroscopy and complementary biophysical techniques to explore protein conformational landscapes, with particular relevance to cancer biology through his affiliation with the UNC Lineberger Comprehensive Cancer Center.