Andreas Waha

استاد · Glioma Epigenetics

Rhenish Friedrich Wilhelm University of Bonn

Germany

معرفی

Prof. Andreas Waha directs neuropathology research at University Hospital Bonn, focusing on epigenetic mechanisms in gliomas. His lab develops clinical diagnostic tools including PyroSequencing assays for BRAF/IDH mutations and MGMT promoter methylation analysis.

Key discoveries include TET1 inactivation in IDH wild-type gliomas and MTSS1 tumor suppressor functions. Waha's group validates DNA methylation signatures for glioma classification and leads phase II trials investigating bortezomib-temozolomide combinations for recurrent glioblastoma.

حوزه‌های پژوهشی

Glioma Epigenetics Molecular Diagnostics MGMT Methylation Biomarker Validation Therapeutic Resistance

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