Thomas Becker

Professor Thomas Becker directs the Institute of Biochemistry and Molecular Biology at the University of Bonn. His laboratory investigates mitochondrial biogenesis mechanisms, focusing on protein import quality control, outer membrane assembly, and translocase networks.

Key discoveries include:

• Mitochondrial protein translocation-associated degradation (mitoTAD) pathway
• Porin's dual role in metabolite transport and protein import
• MIM complex mechanisms for α-helical membrane protein insertion

Research combines biochemical approaches with proteomics to study how mitochondria integrate protein transport with metabolic regulation and organelle contact sites.