معرفی
Alistair McGregor, PhD is a Professor in the Department of Microbial Pathogenesis & Immunology at Texas A&M University's School of Medicine. His research focuses on cytomegalovirus (HCMV) pathogenesis, vaccine development, and antiviral strategies using guinea pig models. He holds a PhD in Virology from the University of Glasgow (1994), followed by postdoctoral training at UC Berkeley and Cincinnati Children's Research Hospital.
Research interests include understanding congenital CMV transmission mechanisms, developing live-attenuated vaccines, and studying viral immune evasion strategies. His lab employs cutting-edge techniques such as bioluminescence imaging and genetically engineered viral mutants. Current NIH/NIAID-funded projects investigate vaccine efficacy and placental infection pathways.
Key contributions include demonstrating ganciclovir's limitations in preventing congenital CMV and establishing the guinea pig as a critical preclinical model. His work bridges basic virology with translational medicine, aiming to reduce CMV-associated birth defects and improve antiviral therapies.
- Grants: Active NIH/NIAID funding
- Labs/Teams: McGregor Lab Virus Research
- Future Work: Optimizing multivalent vaccines, understanding placental immune responses, developing non-invasive diagnostic tools
