
Alison Bernstein
استادیار · Neurodegenerative Diseases
Washington University in St. Louisمعرفی
Alison Bernstein, PhD, serves as an Assistant Professor at Michigan State University, focusing on molecular mechanisms of neurodegenerative disorders with particular emphasis on Parkinson's disease pathogenesis.
Her research program investigates oxidative stress-induced neuronal injury through toxin-based models, examining critical pathways involving p53, PUMA protein, and the unfolded protein response. Key methodologies include 6-OHDA and MPP+ neurotoxin exposure systems to dissect cell death mechanisms and DNA damage responses in dopaminergic neurons.
Publication analysis (2009-2013) reveals consistent investigation of Parkinson's disease molecular triggers, with evolving focus from protein oxidation responses (2009) to specific cell death pathways (2011-2013). Her work bridges molecular neuroscience and toxicology, highlighting oxidative damage as central to neurodegeneration.
Dr. Bernstein earned her doctoral degree in 2009 under Karen O'Malley with dissertation research on PUMA's role in Parkinson's toxin models. Current advising activities and grant funding details are not specified in available materials, though her publication record demonstrates active laboratory-based research in neurodegenerative mechanisms.
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