Alice O Silva

Alice O Silva is an Associate Professor in the Departments of Immunology & Immunotherapy and Oncological Sciences at the Icahn School of Medicine at Mount Sinai. Her research focuses on T cell biology, particularly in chronic antigen stimulation contexts such as cancer. She investigates how inflammation, costimulation, and microenvironmental factors influence CD8 T cell differentiation, dysfunction, and responsiveness to immunotherapy. Her work combines mouse models of chronic viral infection and tumor analysis with clinical samples from cancer patients.

She holds a PhD from Rockefeller University and completed a postdoctoral fellowship at Emory University. Her lab explores interventions targeting PD-1 signaling pathways and aims to identify molecules/pathways to enhance immunotherapy efficacy. Office locations include the Icahn (East) Building, 12th Floor (Rooms 12-02 and 12-20A), New York, NY 10029. Contact phone numbers are provided but no email is explicitly listed in the text.