معرفی
Alexey Bersenev, MD, PhD, is an Assistant Professor in the Department of Laboratory Medicine at Yale School of Medicine. He specializes in cellular and cell-gene therapies, focusing on developing and translating advanced therapeutic strategies into clinical applications. His work bridges laboratory research with regulatory and manufacturing challenges in bringing investigational cell products to clinical trials.
Education:
- MD, Izhevsk State Medical Academy (2000)
- PhD, Institute of Transplantology and Artificial Organs (2003)
Dr. Bersenev's research centers on regenerative medicine, particularly mesenchymal stromal cells, CAR-T therapy, and bioprocessing methods for scalable and consistent manufacturing of cell-based therapeutics. He investigates how advanced cell processing and gene modification can enhance treatment efficacy while ensuring regulatory compliance and clinical safety. His work is critical in translating cutting-edge therapies from bench to bedside.
His recent publications highlight trends in cell and gene therapy, including meta-analyses of clinical outcomes, CRISPR-based enhancement of CAR-T cells, and the development of infrastructure for delivering externally manufactured therapies. These works reflect a strong focus on translational innovation, manufacturing scalability, and clinical implementation.
Scientific Awards:
Dr. Bersenev collaborates extensively with clinical and research teams at Yale, including frequent co-authorship with experts such as Diane Krause, Emanuela Bruscia, Paul Clark, Ruth R. Montgomery, Sidi Chen, and Wade Schulz. While no formal advising of students is mentioned, his research contributes to advancing the field through collaborative science and innovation in therapeutic delivery systems. He is actively involved in shaping best practices for cell therapy implementation in academic medical centers.
Labs and Teams: He contributes to research initiatives within the Yale Center for Cellular and Molecular Imaging (YCCMI) and the Yale Stem Cell Center, and is affiliated with the Apheresis/Transfusion Service and Blood Bank within Laboratory Medicine.
