Alexander Stewart

Dr Alexander Stewart is a Research Fellow in Immunology at the University of Surrey's School of Biosciences, part of the Faculty of Health and Medical Sciences. His work focuses on immune system dynamics, antibody repertoire analysis, and eco-immunological mechanisms. He specializes in integrating multi-omics approaches to study B cell biology, viral immunity, and host-parasite interactions. Key research areas include immunoglobulin gene diversification, metabolic regulation of immune cells, and the impact of environmental factors on immunocompetence.

Stewart has contributed to tools like BRepertoire, a web server for antibody repertoire analysis, and sciCSR for inferring B cell state transitions. His research spans experimental models (e.g., three-spined stickleback, chickens) and human studies, including investigations into SARS-CoV-2 pathogenesis and glucocorticoid treatment effects. He explores cross-species immune mechanisms, from parasitic infections in rodents to lunar-driven immune rhythms in fish.

His recent work highlights the role of CSF1R in macrophage biology and the metabolic control of regulatory B cells. He also examines antibody class-switching dynamics and the evolutionary basis of immunoglobulin diversity. Stewart's findings bridge basic immunology with translational applications in infectious disease and cancer research.