Alexander Khoruts

Dr. Alexander Khoruts is a Professor in the Department of Medicine at the University of Minnesota, where he serves as Section Lead for Luminal GI MEC and Director of the UMN Microbiota Therapeutics Program. His academic roles focus on advancing microbiota-based therapies for gastrointestinal and systemic diseases.

• Primary Affiliation: Division of Gastroenterology, Hepatology and Nutrition
• Leadership: UMN Microbiota Therapeutics Program

Dr. Khoruts’ research spans fecal microbiota transplantation (FMT), microbial dysbiosis, and gut-liver axis interactions. His work examines how microbiome alterations impact conditions like inflammatory bowel disease (IBD), hepatic encephalopathy, and post-transplant complications. Key themes include microbial engraftment dynamics, antibiotic resistance gene transfer, and metabolomic profiling.

Recent publications highlight FMT applications in ulcerative colitis, cirrhosis, and autism, with technical innovations in metagenomic source tracking and microbial formulation development. He actively investigates microbiome contributions to acute myeloid leukemia and pulmonary arterial hypertension outcomes.