Aleksejs Sazonovs

Aleksejs Sazonovs is an Associate Professor in the Department of Clinical Medicine at Aarhus University, Faculty of Medicine, where he is a key member of the Center for Molecular Prediction of Inflammatory Bowel Disease. His research integrates large-scale genomics and computational methods to uncover the genetic basis and clinical variability of inflammatory bowel disease (IBD).

Education:

• PhD in Mathematical Genomics and Medicine, University of Cambridge (awarded December 18, 2019)
• BSc (Hons) in Computer Science, University of St Andrews (awarded July 1, 2015)

Dr. Sazonovs' research focuses on applying genome-wide association studies, polygenic risk modeling, and longitudinal biomarker analysis to understand IBD pathogenesis and progression. His work emphasizes precision medicine approaches to predict disease onset and severity, particularly through genetic and immune profiling. The integration of computational biology with clinical data enables novel insights into disease heterogeneity and treatment response.

His recent publications (2024–2025) highlight trends in genetic risk prediction for IBD severity, HLA associations with ulcerative colitis, and clustering of inflammatory biomarkers over time. These works span high-impact journals such as JAMA and Gastroenterology, as well as preprint servers and conference proceedings, indicating active engagement in both peer-reviewed and emerging scientific communication.

Scientific Awards:

Dr. Sazonovs serves as Principal Investigator for the project "Decoding IBD genetics," which began in January 2024 and is currently active. While no formal advisees are listed, his collaborative research includes co-authorship with multiple researchers and clinicians. His work has attracted media attention, including coverage in 19 news outlets and discussion on social media platforms, reflecting public and scientific interest in his findings on IBD prediction and genetics.

Labs and Research Teams: He is affiliated with the Center for Molecular Prediction of Inflammatory Bowel Disease at Aarhus University, a multidisciplinary research group focused on integrating molecular data for clinical prediction in IBD.