معرفی
Aleksandar Jeremic is a Professor of Biology and Undergraduate Advisor at The George Washington University's Department of Biological Sciences. His research focuses on molecular neuroendocrinology, nanobiology, and islet amyloidosis with strong emphasis on Type 2 Diabetes Mellitus (T2DM) pathology.
Education:
- B.S., University of Belgrade (1994)
- M.S., University of Belgrade (1996)
- Ph.D., Iowa State University (2001)
- Post-Doctoral Work: Wayne State University School of Medicine (2002-2006)
Research integrates high-resolution imaging techniques (optical, force, spectral), X-ray crystallography, and spectroscopy to investigate pancreatic β-cell machinery. Key foci include:
- 3D organization of insulin release machinery
- Amylin aggregation mechanisms in T2DM
- Therapeutic ultrasound applications
- Membrane cholesterol dynamics
- Water channel regulation
Publications reveal consistent contributions to understanding
- β-cell secretory mechanisms (2001-2012)
- Amyloid formation dynamics (2013-2022)
- Ultrasound-based diabetes therapies (2016-2025)
- SNARE complex biophysics (2004-2006)
- Porosome structure-function relationships (2004-2012)
Laboratory employs atomic force microscopy (AFM), confocal imaging, and spectral ultrasound to study
- Insulin secretion at molecular level
- Amyloid fibril formation
- Cell membrane dynamics
- Ion channel activities
- Secretory pore architecture
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