معرفی
Alejandro Ochoa is an Assistant Professor of Biostatistics & Bioinformatics at Duke University, affiliated with the Duke Center for Statistical Genetics and Genomics, Duke Institute for Brain Sciences, and the Center for Combinatorial Gene Regulation. His research focuses on statistical genetics and computational biology, addressing challenges in population structure estimation, genetic association models, and heritability analysis with applications to multi-ethnic studies and admixed populations.
- Education: Ph.D. in Quantitative and Computational Biology from Princeton University (2013)
Research Highlights: Develops scalable statistical methods for genetic studies under arbitrary relatedness, emphasizing equity in multi-ethnic cohorts. Key contributions include software packages like popkin (kinship estimation), ligera (robust association studies), and bnpsd (admixed population simulation). His work addresses biases in principal component analysis, heritability estimation, and GWAS meta-analysis.
Grants:
- National Institutes of Health (2023-2026): Regulators of Calcineurin Pathways as Diagnostic and Therapeutic Targets for Nephrotic Syndrome
- National Institutes of Health (2020-2026): HLA Risk Alleles in Primary Nephrotic Syndrome
- National Human Genome Research Institute (2020-2025): Duke FUNCTION Center
Labs & Collaborations: Leads the Ochoa Lab, which develops open-source software under GNU General Public License and collaborates with programs like UPGG and CBB.
