معرفی
Carl F. Pieper is Professor of Biostatistics & Bioinformatics in the Division of Biostatistics at Duke University, with a primary appointment at 1513 Busse Building, Durham, NC 27710. A Columbia-trained DrPH (1990), he has steadily advanced from Assistant Research Professor to full Professor at Duke, focusing on advanced statistical methods for medical research.
Research Interests:
- Design of Medical Experiments: reliability/generalizability models, powering longitudinal trials with multiple outcomes and missing data.
- Analysis of Repeated Measures & Longitudinal Data: hierarchical linear & mixed models for simultaneous estimation of multivariate trajectories.
- Substantive Domains: gerontology, geriatrics, psychiatry, and multivariate repeated measures.
Across his 2025 publications, Pieper’s work converges on aging-related outcomes—functional decline, polypharmacy, multimorbidity trajectories, metabolic pathways, and psycho-social determinants—leveraging large cohorts (CARDIA, CALERIE, SWET-RA, NHANES-based samples) and employing sophisticated longitudinal modeling to inform clinical decision-making in older adults.
Grants & Funding:
- NIH R01: Measuring Racial Equity and Institutional Racism in Primary Care (EQUIP) (2024-2028)
- NIA R21: Effect of Acetylcholinesterase inhibitors on Bone Metabolism and Fracture Risk in Alzheimer’s Disease (2023-2026)
- Tufts subcontract: Legacy Effects of CALERIE Caloric Restriction on Aging Hallmarks (2022-2026)
- NIH R01: Influence of Vision Impairments on Dementia in Stroke Survivors (2023-2026)
- UNC pilot: Feasibility of Time-Restricted Feeding in Mild Cognitive Impairment (2023-2026)
- NIA cooperative agreement: Behavior and Physiology in Aging (2015-2025)
- NHLBI R01: Sickle Cell Disease Functional Assessment & Exercise Intervention (2023-2025)
- CDC contract: Strategic Use of Race/Ethnicity Data in NHSN Measures (2022-2025)
Teaching & Mentorship: Pieper leads the graduate course CRP 263: Longitudinal Data Analysis at Duke, mentoring trainees in biostatistics and collaborative health research.
His Duke affiliation and sustained NIH/CDC funding place him at the forefront of statistical innovation for aging research.
