معرفی
Prof. Dr. Albrecht Schwab is a faculty member at the Institute of Physiology II, affiliated with the Medical Faculty of Münster University. He leads the Cell Migration Group, focusing on the role of ion channels and ion transporters in tumor and immune cell migration. Key research areas include calcium signaling, pH regulation, and mechanosensitivity in cancer progression and neutrophil function.
- Department: Institute of Physiology II
- University: University of Münster
- Research Networks: Cells in Motion, pHioniC (2018-2023), IonTraC (2011-2015)
His work investigates how ion transport proteins like KCa3.1, TRP channels, and the Na+/H+ exchanger (NHE1) drive cancer metastasis and immune cell chemotaxis. Projects include mechanosignaling in pancreatic stellate cells, TRP channel roles in neutrophil activation, and epigenetic dysregulation of ion channels in lung cancer. Techniques employed include time-lapse videomicroscopy, live-cell fluorescence, and atomic force microscopy.
Articles highlight trends in ion channel imaging (PET/fluorescent probes), mechanotransduction in fibrosis, and calcium/pH signaling in melanoma and pancreatic cancer. The lab collaborates with technical staff (Ilka Neumann, Sarah Sargin, Sandra Schimmelpfennig) and participates in European research consortia.
