معرفی
Albert Lee is an Associate Professor at Macquarie University's Macquarie Medical School and leads the Neuroproteomics Research Group within the Motor Neuron Disease Research Centre. His career spans academic research and education, with a focus on understanding cellular survival mechanisms in neurodegenerative diseases like ALS and FTD. He holds a PhD from Macquarie University and completed postdoctoral training at Johns Hopkins University and New York University.
Education:
- B.Sc. Molecular Biotechnology (2004, University of Sydney)
- M.Biotech(Hons I)/Business (2006, Macquarie University)
- Ph.D. in Proteomics (2011, Macquarie University)
Research Interests: Dr. Lee's work integrates proteomics to study post-translational modifications (e.g., ubiquitination, phosphorylation) and their roles in neurodegeneration. His lab focuses on TDP-43 pathobiology, SCFCyclin F dysfunction in ALS/FTD, and translational proteomics for disease biomarkers. Collaborative projects include NHMRC Dementia Teams Grants and industry partnerships.
Articles Trends: Recent studies highlight TDP-43 aggregation mechanisms, mitochondrial dysfunction in Machado Joseph disease, and therapeutic strategies targeting autophagy. His proteomic approaches uncover novel pathways linking ubiquitin ligase defects to neurodegeneration.
Awards:
- 2020 HDR Supervisor Award (Macquarie University)
- 2021 Faculty Teaching Excellence Award
- NHLBI Postdoctoral Fellowship (2011–2013)
Advising & Grants: Supervised 19 students across PhD/MRes programs and leads 37 active projects, including NHMRC-funded initiatives and industry grants. His Neuroproteomics group employs 3 postdocs and 2 research assistants.
Labs & Teams: Heads the Neuroproteomics Research Group, collaborating with the Australian Proteome Analysis Facility (APAF) and the Macquarie Centre for MND Research. Active in interdisciplinary teams targeting ALS/FTD biomarkers and therapeutics.
