Adam P Lightfoot

Dr Adam P Lightfoot is a Senior Lecturer in Physiology at Manchester Metropolitan University's Department of Life Science. His research focuses on mitochondrial dysfunction in neuromuscular diseases, obesity, and aging. He has secured over £800k in grants from organizations like The Royal Society and Myositis UK. His work includes developing human pre-clinical models of muscle diseases and studying muscle-adipose crosstalk in sarcopenic obesity. Recent projects explore statin-induced myopathy and pharmacotherapy's impact on musculoskeletal health.

Education:

• BSc (Hons) Biomedical Sciences, 2006
• MRes Cell Biology, Gothenburg University, 2007
• PhD, University of Liverpool, 2011 (Skeletal Muscle Endocrine Role)

Research Interests: Dr Lightfoot investigates mechanisms underlying muscle weakness in myositis, mitochondrial dysfunction, and the interplay between muscle and adipose tissue. His lab employs advanced co-culture systems and metabolic analyses to study these processes. He collaborates with Dr Nasser Al-Shanti to develop human-relevant muscle disease models.

Grants & Awards:

• Mersey Kidney First Award (Postdoc, 2013)
• Royal Society Grant (2018)
• Physiological Society Fellowship (2018)

Advising & Labs: Accepts self-funded MRes/PhD students. Active in lab development for neuromuscular junction modeling and muscle-adipose crosstalk studies.