Adam Greenstein

Adam Greenstein is a Clinical Professor and clinician scientist at the University of Manchester, holding a joint appointment in the Division of Cardiovascular Sciences. He is a consultant physician at Manchester University Hospitals Foundation Trust, specializing in hypertension, geriatric care, and obesity-related hypertension. His dual clinical-research role combines treating patients with vascular dementia and hypertension with leading a laboratory investigating hypertension-induced vascular damage and obesity-driven hypertension mechanisms.

Education: BSc(Hons) Pharmacology (1994), MBChB (1997), PhD (2009) from the University of Manchester. He completed a BHF Travel Fellowship in Vascular Physiology at the University of Vermont and a BHF Intermediate Clinical Research Fellowship (2012-2016).

Research focuses on hypertension's role in small vessel disease of the brain (linking to vascular dementia) and obesity-related hypertension. Key techniques include pressure myography, confocal microscopy, and electrophysiology. His lab uses advanced imaging (e.g., Andor Revolution XD microscope) to study intracellular calcium signaling in vascular tissues. Major funding comes from the British Heart Foundation (BHF), including grants for infrastructure and PhD studentships.

Notable achievements include the 2020 'Best Basic Science Paper' award from the American Heart Association for obesity hypertension work. His research has been featured in high-impact journals like PNAS and JCI, and he collaborates internationally (e.g., with Prof. Mark Nelson, University of Vermont).

Funding and grants: BHF Centre for Research Excellence (2024-2029), BHF PhD Studentships (2018-2023). Active in professional bodies: British and Irish Hypertension Society (Executive Committee), International Society for Hypertension.

Labs/Teams: Leads a cutting-edge small artery laboratory at the University of Manchester, part of the BHF-funded infrastructure. Collaborates on multidisciplinary projects like the 'Vascular Contributions to Dementia' initiative.