معرفی
Achilleas Garoufis is a full Professor in the Department of Chemistry at the University of Ioannina, where he has served since 2015 after progressing through academic ranks from Lecturer (2000) to Assistant Professor (2005) and Associate Professor (2010). His primary appointment resides within the Chemistry department with no explicit school affiliation mentioned in available materials. His research spans inorganic and bioinorganic chemistry with emphasis on metal-based anticancer agents.
Garoufis' research program focuses on the design and characterization of platinum group metal complexes (particularly ruthenium, palladium, and platinum) conjugated to biomolecules. His work investigates DNA binding mechanisms using spectroscopic and bioanalytical techniques, with applications in photodynamic therapy and cytostatic drug development. Key methodologies include NMR, CD, LD spectroscopy, electrophoresis, and ESI-MS for studying metal-nucleic acid interactions.
Analysis of his 15 most recent publications (2021-2025) reveals consistent focus on ruthenium and platinum anticancer complexes, DNA binding specificity, and photophysical properties of supramolecular structures. His work increasingly incorporates advanced structural characterization of metal complexes with DNA oligomers and explores novel scaffolds like cycloparaphenylene systems for enhanced cytotoxicity. Recent publications also demonstrate expansion into analytical applications of NMR for food chemistry, particularly olive oil authentication.
Garoufis has authored several textbooks including Inorganic elements in the environment, life and technology (2005) and Inorganic Chemistry (1999), and has translated Cotton & Wilkinson's BASIC INORGANIC CHEMISTRY. His teaching portfolio covers undergraduate and graduate courses in Inorganic Chemistry, Bioinorganic Chemistry, Mass Spectrometry, and NMR Spectroscopy.
His academic development includes undergraduate and doctoral studies at the University of Ioannina (BSc 1985, PhD 1989), followed by postdoctoral work at the University of Bergen (1993-1994), VUB Brussels (1994-1995), and Zhongshun University (1999). Current research continues to advance metal-based therapeutic strategies with emphasis on structure-activity relationships in DNA-targeting complexes.
