Abe Clark

Abe Clark is a Professor at the University of North Texas Health Science Center, holding dual appointments in the College of Biomedical and Translational Sciences and the North Texas Eye Research Institute. He specializes in Pharmacology & Neuroscience with a focus on ocular diseases. His primary research centers on molecular mechanisms of glaucoma pathogenesis and translational therapies.

Education:

• BA in Biology, Thiel College
• PhD in Microbiology, Case Western Reserve University

Research Interests:

• Molecular pathogenesis of eye diseases
• Glaucoma therapeutic target discovery
• Neurodegenerative mechanisms in vision loss
• In vitro/ex vivo/in vivo disease modeling

His work integrates molecular genetics, cell biology, and mouse models to develop disease-modifying therapies.

Grant Activity:

• Active NIH grants (NEI) targeting FMNL2/Rho-GTPase pathways and glucocorticoid effects
• University of Texas collaboration on photoreceptor neuroprotection

Over 49 sponsored projects since 2005 demonstrate sustained research impact.

Labs/Teams:
Leads a lab focused on translational glaucoma research, mentoring graduate students, postdoctoral fellows, and medical students through hands-on training in advanced techniques including ex vivo organ culture and genome editing.