A.F.M. Altelaar

Prof. A.F.M. Altelaar holds a Professorship in Biomolecular Mass Spectrometry and Proteomics at Utrecht University's Faculty of Science. His research focuses on advancing mass spectrometry techniques for protein characterization and post-translational modification analysis, particularly in cancer signaling and drug resistance mechanisms. He pioneered label-free phosphopeptide quantification and cross-omics approaches to study system-wide biological responses. He received a 2013 VIDI grant for cancer proteomics research and leads major initiatives like the Netherlands Proteomics Center. Currently serves as treasurer of the International Mass Spectrometry Foundation.

Research emphasizes improving proteomics' sensitivity, specificity, and throughput, with applications in drug sensitivity studies and cellular signaling networks. Notable contributions include SRM-based phosphorylation dynamics tracking and drug resistance mechanisms analysis. Professional activities include executive director roles at Ambagon Therapeutics and collaborations in international proteomics consortia.