Subcellular Localization Professors and Supervisors | ApplySharif

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Anna Newman-GriffisView profile

Assistant Professor

Durham UniversityUnited Kingdom

Anna Newman-Griffis is an Assistant Professor in the Department of Biosciences within Durham University's Faculty of Science. A Fellow of the Higher Education Association (FHEA), she has received multiple teaching accolades including the UCL Faculty of Life Sciences Education Award (2023) and The Ohio State University Center for Life Sciences Education Outstanding Teaching Award (2019). Her research focuses on plant nuclear architecture, investigating how nuclear morphology and positioning respond to developmental cues and environmental stimuli. She specializes in symbiotic mechanisms like root nodule formation in Medicago, nuclear movement dynamics, and the role of LINC complexes in plant cell biology. Her work bridges fundamental cellular processes with agricultural implications through model systems including Arabidopsis and Medicago. Publication trends from 2014-2024 reveal consistent contributions to plant cell biology with increasing emphasis on science communication and educational innovation. Her recent work includes public-facing science writing (2024) and pedagogical resources for undergraduate research training (2020), demonstrating dual expertise in research and science education. Key recognitions include: Fellow of the Higher Education Association (2024) UCL Faculty of Life Sciences Education Award (2023) The Ohio State University Center for Life Sciences Education Outstanding Teaching Award (2019) She actively enhances undergraduate education through the SEA-PHAGES program, developing data analysis frameworks for Course-based Undergraduate Research Experiences that strengthen student engagement in biological research methodologies.

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Jeff WallerView profile

Associate Professor

Mount Allison UniversityCanada

Jeff Waller is an Associate Professor at Mount Allison University, leading the Waller Lab. His research focuses on understanding the biochemical mechanisms behind dimethylsulfoniopropionate (DMSP) synthesis and metabolism in marine algae and bacteria. DMSP plays a critical role in global sulfur cycling and climate regulation via its breakdown product dimethylsulfide (DMS). His work combines genomic approaches, enzyme purification, and biochemical characterization to identify key enzymes and their roles in diverse algal species. Research interests include marine microbiology, biogeochemistry, and the interplay between algal physiology and global environmental processes. His lab employs comparative genomics, bacterial complementation assays, and classical protein purification techniques to uncover DMSP biosynthetic pathways. The long-term goal is to predict DMSP production capacity across algal genomes and understand enzyme regulation under varying environmental conditions. Publications span topics from DMSP uptake dynamics in polar diatoms to iron-sulfur cluster metabolism and NAD kinase functions in plants. While no specific grants or student advisees are listed, his research emphasizes interdisciplinary approaches to solve fundamental questions in microbial biochemistry and environmental science. The Waller Lab’s facilities include tools for genomic analysis, protein characterization, and metabolic pathway exploration.

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Maureen Le BarsView profile

Lecturer

ETH ZurichSwitzerland

Dr. Maureen Le Bars is a Lecturer at the Department of Environmental Systems Science, ETH Zurich. Her research focuses on environmental chemistry, biogeochemistry, trace element cycling, soil science, microbial processes, and nanoparticle fate. She investigates interactions between organic matter, minerals, and trace elements like mercury, copper, and zinc in soils and waste systems. Her work emphasizes microbial contributions to mercury methylation, nanoparticle behavior in environmental matrices, and sustainable waste recycling. Recent studies include mercury dynamics in soils and anaerobic bacteria, copper speciation during waste treatment, and zinc sulfide nanoparticles' instability during composting. Publications highlight methodological innovations like synchrotron-based imaging and X-ray spectroscopy. No scientific awards are explicitly listed. While no student advisees are documented, her research spans interdisciplinary topics such as microbial biofilms' roles in nanoparticle fate and Arctic soil mercury transformations.

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Anson TanView profile

Research Fellow

University of QueenslandAustralia

Dr Anson Tan is a Postdoctoral Research Fellow at the Queensland Brain Institute , University of Queensland, specializing in molecular mechanisms of membrane trafficking in neurons. His work explores how dysregulated trafficking contributes to neurodegenerative diseases (e.g., ALS, Alzheimer's) and neuropsychiatric disorders. Education: PhD in Protein Trafficking (University of Melbourne, 2018) Research Interests: Synaptic transmission, protein sorting, DNA repair in neurodegeneration Scientific Awards include the UQ Postdoctoral Researcher Retention Fellowship (2022), Dean’s Honour List (University of Melbourne, 2012), and Best Poster Award (COMBIO 2015). He has published extensively on Golgi trafficking, amyloid processing, and calcium signaling in synaptic plasticity. Recent Publications: FTO suppresses DNA repair by inhibiting PARP1 (2025) Copine-6 is a Ca2+ sensor for AMPA receptor exocytosis (2023) ALS-associated SFPQ mutations and cytoplasmic aggregates (2022) Dr Tan is currently affiliated with the Clem Jones Centre for Ageing Dementia Research and advises on projects related to epigenetic regulation of memory, synaptic signaling, and Copine-6 lipid-binding mechanisms. He collaborates with Professor Victor Anggono and Dr Jocelyn Widagdo on neurotrafficking studies.

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Nick AriottiView profile

Academic

University of QueenslandAustralia

Dr Nick Ariotti is a Senior Research Fellow and Group Leader at the Institute for Molecular Bioscience (IMB), University of Queensland. His research focuses on understanding the three-dimensional structure of cells at molecular resolution, particularly investigating endocytic processes and protein trafficking. His lab employs advanced cryogenic light and electron microscopy to study how dysregulation of lipids and proteins in the plasma membrane and endosomes contributes to diseases like cardiovascular disorders and cancers. Key projects include studying caveolae structure, cargo specificity in intracellular trafficking, and the role of eNOS in cardiovascular disease. Research techniques include correlative cryo-light and electron microscopy, super-resolution fluorescence microscopy, and genome-editing tools. Collaborations with groups at IMB, UNSW Sydney, and others drive interdisciplinary approaches. His team includes postdocs, research officers, and PhD students like Muze Cheng. The lab’s work targets novel drugable mechanisms for cardiovascular diseases and integrates structural and cellular biology. Education: Advanced degrees in molecular biology/structural biology (details not explicitly stated in text). Collaborators: Parton Group, Collins Group, Ananthanarayanan Group (EMBL Australia). Labs/Teams: The Ariotti Group at IMB’s Centre for Cell Biology of Chronic Disease. Publications span structural biology, virology, and cellular mechanisms, with a focus on lipid-protein interactions and disease models. Ongoing work explores mechanosensitive cell surface changes and mitochondrial dynamics.

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Jennifer StowView profile

Professor

University of QueenslandAustralia

Professor Jennifer Stow is a Group Leader at the University of Queensland's Institute for Molecular Bioscience (IMB), specializing in protein trafficking and inflammation. Her research focuses on understanding molecular mechanisms underlying inflammation, particularly in immune cells like macrophages. She leads projects investigating macropinocytosis, Toll-like receptor (TLR) signaling, cancer cell survival, and cilia dysfunction in kidney diseases. Her team employs advanced microscopy and proteomic approaches to study cellular pathways. Key achievements include discovering SCIMP's role in TLR signaling and macropinocytosis's role in cancer. She was elected to EMBO (2019), a prestigious recognition of her contributions to cell biology. Her interdisciplinary collaborations span IMB's Centre for Inflammation and Disease Research and global partners. Students under her mentorship include Hongyu Shen, Sylvia Tan, Vrushali Maste, and Wanyi Wang. She holds an NHMRC Leadership Fellowship and oversees the IMB Microscopy Facility, advancing imaging technologies for biological research. Research highlights include identifying macropinocytosis as a cancer drug target and elucidating cilia dysfunction in inherited diseases. Her work bridges basic science with translational applications, targeting therapies for chronic inflammation, cancer, and kidney disorders.

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Wan Jun GanView profile

Researcher

University of QueenslandAustralia

Dr. Wan Jun Gan is a researcher affiliated with the Institute for Molecular Bioscience at the University of Queensland . Their work spans multiple disciplines including Cell Biology, Molecular Biology, and Diabetes Research. Key research interests include: Cell polarity and cytoskeletal dynamics in C. elegans and pancreatic beta cells Regulation of insulin secretion and beta cell function Mechanisms of HMGB1-RAGE signaling in inflammatory and allergic airway diseases Epithelial tissue tension and its role in disease pathogenesis Recent publications highlight their contributions to understanding: APC mutants and apical cell extrusion in epithelial tissues Integrin and focal adhesion kinase roles in targeting insulin secretion ABCA12's impact on beta-cell physiology HMGB1-RAGE axis in asthma and type-2 inflammation As a collaborator in the Thorn Lab , they utilize advanced techniques in cell imaging and microcontact printing for their studies. Their work bridges fundamental cell biology with translational applications in diabetes and respiratory diseases.

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Steven ZurynView profile

Associate Professor

University of QueenslandAustralia

Associate Professor Steven Zuryn is a molecular geneticist at the Queensland Brain Institute , University of Queensland , within the Faculty of Health, Medicine and Behavioural Sciences. He leads an international team studying epigenetics and mitochondrial biology to uncover mechanisms linking mitochondrial dysfunction to neurodegenerative diseases like Alzheimer's and Parkinson's. His research has been published in Science , Nature Cell Biology , and Cell Metabolism , with funding from NHMRC , ARC , and the Stafford Fox Medical Research Foundation .

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Steven SchwartzbachView profile

Professor

University of MemphisUnited States

Dr. Steven Schwartzbach is a Professor in the Department of Biological Sciences at the University of Memphis. He joined the institution in 2001 after working at the University of Nebraska. His research focuses on chloroplast protein targeting mechanisms, evolutionary plastid biology, and the molecular basis of endosymbiotic organelle acquisition. Dr. Schwartzbach teaches Biology 3130 (Cell Biology) and has contributed to advancements in understanding Euglena's unique cellular systems. Education: B.S. in Biology from SUNY Buffalo, Ph.D. in Biology from Brandeis University, and a postdoctoral fellowship at Oak Ridge National Laboratory under the American Cancer Society. Research interests include the ER-to-Golgi-to-chloroplast protein transport pathway, plastid genome reduction, and the evolutionary mechanisms behind complex plastids (e.g., Euglena's three-membrane chloroplasts). His work bridges biochemistry, cell biology, and evolutionary studies, with a focus on photoregulation and organelle biogenesis in euglenids. Publications emphasize cutting-edge methodologies like immunoelectron microscopy and advanced genetic transformation systems. His research has implications for understanding organelle evolution, biotechnology applications in algae, and pathogen cell biology (e.g., Giardia). Key contributions include elucidating Euglena's polyprotein precursor processing, trans-spliced mRNA mechanisms, and the role of endosymbiotic events in organelle complexity. Current projects explore plastid genome essentiality and evolutionary pathways.

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Caroline UhlerView profile

Professor

Massachusetts Institute of TechnologyUnited States

Caroline Uhler is the Andrew (1956) and Erna Viterbi Professor of Engineering at MIT, holding joint appointments in the Department of Electrical Engineering and Computer Science (EECS) and the Institute for Data, Systems, and Society (IDSS). Her research focuses on the intersection of machine learning, statistics, and computational biology, with particular emphasis on causal inference, genomics, and healthcare technologies. She leads interdisciplinary projects in AI+D (Artificial Intelligence for Data Science) and collaborates across MIT’s School of Engineering. Her work spans theoretical foundations of causal discovery, algorithm development for biological systems, and applications in precision medicine. Notable contributions include methods for analyzing single-cell data, protein structure prediction, and mechanistic modeling of cellular processes. Recent research highlights include predicting protein localization, modeling gene regulation via chromatin imaging, and identifying tumor microenvironment factors in Hodgkin lymphoma. Awards: Andrew and Erna Viterbi Professorship (20XX). Key Areas: Causal machine learning, systems biology, computational genomics. Labs/Teams: Integrates computational methods with experimental biology, leading MIT’s efforts in AI-driven healthcare research. Uhler’s lab develops tools for analyzing high-dimensional biological data, with applications to drug discovery and disease mechanisms. Her work bridges theoretical computer science and experimental biology, emphasizing the role of causal models in understanding complex systems.

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Thoru PedersonView profile

Professor

University of Massachusetts Chan Medical SchoolUnited States

Thoru Pederson is the Vitold Arnett Professor of Cell Biology at UMass Chan Medical School and Associate Vice Provost for Research. His pioneering work has transformed understanding of nuclear organization, particularly nucleolar functions beyond ribosome biogenesis, including microRNA localization and stress responses. His laboratory discovered signal recognition particle (SRP) assembly in the nucleolus and identified nucleolar microRNAs. Current NSF-funded research investigates the nucleolus as a multifunctional domain housing cell cycle regulators and examines nuclear body formation through phase separation mechanisms. His laboratory employs cutting-edge techniques including CRISPR-based genome imaging and fluorescence correlation spectroscopy. Pederson has received the Wilhelm Bernhard Medal and Medal of Charles University for nuclear research. He serves on editorial boards for Journal of Cell Biology, Molecular Biology of the Cell, and FASEB Journal, and chairs the Marine Biological Laboratory's Research Awards Committee. His career contributions include seminal studies on RNA trafficking and nuclear dynamics. Beyond research, he writes extensively on science policy, biomedical ethics, and historical perspectives in cell biology.

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Po-Ju ChenView profile

Research Fellow

University of Michigan-Ann ArborUnited States

Po-Ju Chen is a Research Fellow in the Department of Biomedical Engineering at the University of Michigan. Their work focuses on neural engineering and neurophysiology, particularly investigating pudendal nerve stimulation, neuromuscular junction dynamics, and neural recruitment mechanisms. They are affiliated with the pNEURO Lab and operate from the NCRC facility in Ann Arbor, Michigan. Research interests include: Neural recruitment patterns during pudendal nerve stimulation Neuromuscular synapse maintenance and regulation Computational modeling of patient-specific neural responses Medical imaging techniques for neurostimulator placement Role of dystrophin-glycoprotein complexes in synaptic stability Their recent publications highlight trends in neuromodulation for pelvic disorders, postsynaptic receptor dynamics, and hypoxia-related transcriptional responses. Key sub-fields span neural mapping, biomedical imaging, synaptic protein regulation, and microbiome interactions with tissue repair.

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Changyang LinghuView profile

Assistant Professor

University of Michigan-Ann ArborUnited States

Changyang Linghu, Ph.D., is an Assistant Professor in the Department of Cell and Developmental Biology at the University of Michigan. His research focuses on developing innovative tools for molecular recording, optogenetic control, and advanced imaging techniques to study cellular and neural dynamics. He is affiliated with the Spatial Biodynamics Lab and holds a B.Eng. from Tsinghua University and a Ph.D. from MIT. Education: Ph.D., Massachusetts Institute of Technology, 2019 B.Eng., Tsinghua University, 2013 Research Interests: Dr. Linghu’s work spans synthetic biology, neuroscience, and biomedical engineering. He designs novel fluorescent reporters and optogenetic tools to study intracellular processes, neuronal signaling, and complex biological systems. Key themes include molecular recording systems, spatially resolved imaging, and precision optogenetic control of single cells. Publications: His recent work emphasizes scalable gene regulation monitoring, high-speed microscopy innovations, and optogenetic technologies for neural circuit analysis. The research bridges engineering and biology, with applications in understanding cellular memory, signaling networks, and neural activity. Labs & Teams: The Spatial Biodynamics Lab focuses on developing next-generation tools for dynamic biological systems analysis, integrating molecular engineering, imaging, and computational methods.

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Darren WongView profile

Research Fellow

Australian National University (ANU)Australia

Dr Darren Wong is a Postdoctoral Scientist in the Division of Ecology and Evolution at the Australian National University (ANU). His research focuses on molecular mechanisms underlying plant specialization, particularly in orchids and grapevine, with emphasis on specialized metabolites, transcriptional regulation, and stress responses. He investigates how plants adapt to environmental challenges through genetic and metabolic pathways. Key research areas include: plant genetics, molecular biology, specialized metabolites (e.g., floral volatiles, terpenes), transcription factor networks, orchid-fungal symbiosis, and abiotic stress tolerance. His work integrates genomics, transcriptomics, and metabolomics to uncover regulatory mechanisms. Recent studies explore cold tolerance in grapevine via VvbHLH036 transcription factors, parasitism mechanisms in Escobedia grandiflora, and evolutionary drivers of floral color variation. He leads projects on orchid phylogenomics and flower color evolution, funded by ANU grants. Collaborations span international teams studying plant-pollinator interactions, metabolic pathways, and symbiotic relationships. His work bridges fundamental biology with agricultural applications, aiming to enhance crop resilience and understand evolutionary processes.

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Alice TingView profile

Professor

Stanford UniversityUnited States

Alice Ting is a Professor of Genetics, Biology, and Chemistry (courtesy) at Stanford University, affiliated with the School of Humanities and Sciences. She leads the Ting Laboratory, focusing on developing chemical biology tools to probe molecular and cellular networks, with applications in neuroscience, immunology, cancer research, and mitochondrial biology. Her work integrates protein engineering, directed evolution, and proximity labeling technologies to study protein interactions and signaling pathways in living systems. Education: Ph.D. in Chemistry (2000, UC Berkeley, advisor Peter Schultz), A.B. in Chemistry (1996, Harvard University, advisor E.J. Corey), Postdoc in Biochemistry (2002, UC San Diego, advisor Roger Tsien). Affiliated programs include ChEM-H, CMAD, and SSRL at Stanford. Research emphasizes proximity labeling techniques like TurboID and APEX2 for spatial proteomics, RNA localization mapping, and functional interactome analysis. Recent work explores synthetic GPCRs, light-activated toxins, and engineered enzymes for biomedical applications. Her lab's innovations enable high-resolution studies of cellular processes, including synaptic wiring, immune signaling, and mitochondrial dynamics. Publications span 20+ years, with a focus on developing cutting-edge tools for proteomic and transcriptomic analysis, including TransitID, MFB, and LipoID technologies. These methods have advanced understanding of protein trafficking, RNA localization, and host-pathogen interactions. Lab and collaborations: The Ting Group collaborates across disciplines, leveraging Stanford's interdisciplinary environment. Current initiatives include in vivo cell-surface proteomics, synthetic biology for disease modeling, and next-generation proximity labeling platforms.

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