Wan Jun Gan

Dr. Wan Jun Gan is a researcher affiliated with the Institute for Molecular Bioscience at the University of Queensland. Their work spans multiple disciplines including Cell Biology, Molecular Biology, and Diabetes Research.

Key research interests include:

• Cell polarity and cytoskeletal dynamics in C. elegans and pancreatic beta cells
• Regulation of insulin secretion and beta cell function
• Mechanisms of HMGB1-RAGE signaling in inflammatory and allergic airway diseases
• Epithelial tissue tension and its role in disease pathogenesis

Recent publications highlight their contributions to understanding:

• APC mutants and apical cell extrusion in epithelial tissues
• Integrin and focal adhesion kinase roles in targeting insulin secretion
• ABCA12's impact on beta-cell physiology
• HMGB1-RAGE axis in asthma and type-2 inflammation

As a collaborator in the Thorn Lab, they utilize advanced techniques in cell imaging and microcontact printing for their studies. Their work bridges fundamental cell biology with translational applications in diabetes and respiratory diseases.