Rakesh MukherjeeView profile
Research Fellow
Rakesh Mukherjee is a postdoctoral research associate at the Principles of Biomolecular Systems group, Imperial College London . His research focuses on autonomous, enzyme-free molecular templating systems using DNA strands to enable sequence-specific catalytic assembly with minimal product inhibition. Imperial College London (Current: Postdoctoral Research Associate) EPFL (Postdoc: Cyclic Peptide Inhibitors) Ben-Gurion University (PhD: Peptide Replication Networks) Indian Institute of Technology Guwahati (MSc: Organic Chemistry) Research Interests span DNA nanotechnology , molecular replication , and non-covalent/covalent bond engineering . Key work demonstrates: DNA-based catalytic dimerization with weak product inhibition through toehold/handhold displacement Scaling to trimerization and covalent bond formation using copper-catalyzed click chemistry Information propagation in non-biological contexts via sequence-specific templating Applications include: Diagnostics and molecular biophysics through DNA strand displacement circuits Labelled oligomers for downstream tasks like selective binding and gel formation Combinatorial libraries of biologically functional molecules via DNA-templated synthesis











