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William V. GiannobileView profile

Professor

• Periodontology
• Regenerative Medicine
• Tissue Engineering
• +3 more

Dr. William V. Giannobile serves as the Dean and A. Lee Loomis, Jr. Professor of Oral Medicine, Infection, and Immunity at Harvard School of Dental Medicine (HSDM). He leads the institution as its chief academic and administrative officer while maintaining an active research program and clinical practice in periodontics and implant dentistry at the Harvard Dental Center in Cambridge, MA. Dr. Giannobile received his DDS and MS in oral biology from the University of Missouri, followed by a certificate in periodontology and Doctor of Medical Sciences (DMSc) in oral biology from Harvard School of Dental Medicine. He completed postdoctoral training in molecular biology at the Dana-Farber Cancer Institute and Harvard Medical School. With over 30 years of continuously NIH-funded research, Dr. Giannobile's work focuses on oral and periodontal regenerative medicine, tissue engineering, and precision medicine. He serves as principal investigator of the NIDCR U-Award Harvard Clinical Practice-based Research Program for Dental Students (H-CREDENT), which evaluates the genomics of oral pain in a multi-institutional academic setting. His research has produced over 300 manuscripts, textbook chapters, and patents focused on periodontology, regenerative medicine, and oral health research. He has edited or co-edited over 10 books in clinical and translational research, periodontology, and regenerative medicine. His publications demonstrate consistent focus on periodontal regeneration, biomaterials, tissue engineering, and the molecular mechanisms underlying oral diseases. ADA Gold Medal Award for Excellence in Dental Research (2024) International Association for Dental Research Distinguished Scientist Research in Periodontal Disease Award (2022) Norton M. Ross Clinical Research Award from the American Dental Association (2018) William J. Gies Award (2014) Jan Lindhe International Periodontology Research Award (2011) As an educator and mentor, Dr. Giannobile completed a 10-year term as editor-in-chief for the Journal of Dental Research, the official journal of the International Association for Dental Research. He has served as a consultant to the U.S. Food and Drug Administration for Dental Devices and as an associate editor for the NIDCR Report on Oral Health of the U.S. in 2021. His laboratory continues to advance research in periodontal regeneration and precision medicine approaches to oral health, with ongoing NIH funding supporting innovative translational research.

• Mucosal Immunology
• Intestinal Microbiota
• Host-Immune System Interaction
• +3 more

Dame Fiona Powrie is a Professor of Musculoskeletal Sciences at the University of Oxford and Director of the Kennedy Institute of Rheumatology . She leads the Mucosal Immunology Research Group and serves as Director of the Oxford Centre for Microbiome Studies (OCMS) and Cluster Lead in the MRC National Mouse Genetics Network Microbiome Cluster . Roles: Director of Kennedy Institute, Professor, Research Group Leader Relevant Affiliations: Wellcome Trust Governor (2018–present), Deputy Chair (2022), Royal Society Fellow (2011) Research Interests : Fiona specializes in the interplay between the intestinal microbiota and the host immune system, focusing on how dysregulation leads to inflammatory bowel disease (IBD) . Her work has elucidated the role of regulatory T cells in maintaining gut homeostasis and identified the IL-23 pathway as critical in chronic intestinal inflammation. Current efforts aim to translate these findings into clinical therapies for IBD patients. Scientific Awards and Fellowships : Ita Askonas Award (European Federation of Immunological Societies) Louis-Jeantet Prize for Medicine (2012) Honorary Lifetime Membership (British Society of Immunology, 2021) Fellow of the Royal Society (2011), EMBO (2013), Academy of Medical Sciences (2014) International Fellow of the National Academy of Sciences (2020) Advising and Leadership : Fiona leads the Mucosal Immunology group at the Kennedy Institute, mentors researchers, and contributes to national and international scientific governance. She has been instrumental in advancing microbiome and immunology research through leadership roles at the Oxford Centre for Microbiome Studies and the MRC National Mouse Genetics Network . Labs and Teams : Fiona's research group at the Kennedy Institute of Rheumatology investigates mucosal immunity and microbiome interactions, combining experimental and clinical approaches to address inflammatory diseases.

Pixu ShiView profile

Assistant Professor

• Microbiome Research
• Longitudinal/Temporal Omic Data
• Integration of Omic Data
• +2 more

Pixu Shi is an Assistant Professor in the Department of Biostatistics and Bioinformatics at Duke University's School of Medicine. Previously, they served as a Visiting Assistant Professor in the Department of Statistics at the University of Wisconsin-Madison (2018-2020) and as a Postdoctoral Researcher in the Department of Biostatistics at the University of Wisconsin-Madison (2016-2018). Dr. Shi earned their PhD in Biostatistics from the University of Pennsylvania in 2016 under advisor Hongzhe Li. They also hold an MS in Biostatistics from the University of Pennsylvania (2015), an MS in Statistics from Rutgers University (2012), and a BS in Statistics from Peking University (2010). Dr. Shi's research focuses on developing statistical methods for Microbiome Research, Longitudinal/Temporal Omic Data analysis, Integration of Omic Data, Spatial Omics, and High-dimensional Statistical Inference. Their work bridges statistical theory with practical applications in biomedical research, particularly in microbiome studies where they've made significant contributions with the TEMPTED (TEMPoral TEnsor Decomposition) method. The article trends show a strong focus on microbiome analysis, statistical methodology development, and applications in obesity, infectious disease, and cancer research. Their most recent work (2024-2025) demonstrates expertise in tensor decomposition methods, longitudinal data analysis, and integrating microbiome data with clinical outcomes across diverse areas including adolescent obesity, viral infections, and cancer metastases. Dr. Shi has secured multiple substantial research grants from major institutions including the National Institutes of Health (NIMH, NIAID, NCI, NIDDK, NIA), totaling over a decade of continuous funding for projects related to microbiome research, HIV/AIDS, cancer biomarkers, and metabolic studies. They actively contribute to education through teaching courses such as BIOSTAT 905: Linear Models and Inference at Duke University and previously taught statistics courses at the University of Wisconsin-Madison. Dr. Shi has also organized specialized workshop series including Quantitative Methods for HIV/AIDS, Microbiome, Immunology, and Cancer Bioinformatics.

Martin A. KriegelView profile

Professor

• Host-microbiota interactions in autoimmunity
• Gut commensal translocation mechanisms
• Microbiota-induced immune cell migration
• +5 more

Univ.-Prof. Dr. med. Martin A. Kriegel serves as full Professor and Department Head of the Department of Translational Rheumatology and Immunology at the Institute of Musculoskeletal Medicine, University of Münster, while maintaining an active laboratory at Yale School of Medicine. He leads the Section for Rheumatology and Clinical Immunology (SRKI) at Medical Clinic D, where his team integrates clinical care with cutting-edge microbiome research. His department operates from Röntgenstraße 21 and Von-Esmarch-Str. 54 in Münster, Germany, with extensive collaborations including the "Cells in Motion" research initiative and the CiM-IMPRS graduate program. Dr. Kriegel's research program focuses on the critical interface between host immunity and microbiota, particularly investigating how gut commensals translocate to host tissues and trigger autoimmune responses. His laboratory pioneered the discovery that specific pathobionts like Enterococcus gallinarum and certain Lactobacillus strains can translocate from the gut to mesenteric lymph nodes, liver, and other sites, driving autoimmune responses through molecular mimicry of human autoantigens. His work has established fundamental mechanisms by which microbiota influence rheumatic diseases, cutaneous autoimmunity, and cancer immunology, with particular emphasis on Ro60 autoantigen mimicry, TLR7-dependent pathways, and diet-microbiome interactions. The laboratory employs advanced techniques including gnotobiotic mouse models, humanized systems, and detailed molecular characterization of host-pathobiont interactions. Analysis of Dr. Kriegel's publication record reveals a consistent trajectory of high-impact research connecting microbiome dynamics to autoimmune pathogenesis. His most recent work (2023-2025) demonstrates increasingly sophisticated understanding of how specific bacterial strains influence disease phenotypes across multiple autoimmune conditions, with notable advances in identifying shared microbiome signatures across lupus and inflammatory bowel disease. The publications show progressive refinement from initial observations of microbial translocation to detailed mechanistic insights into tryptophan catabolism pathways, structural basis of molecular mimicry, and diet-sensitive microbial triggers. Dr. Kriegel's scientific recognition includes US Patent No. 11,058,756 B2 for compositions treating autoimmune diseases by reducing enterococcus, reflecting the translational potential of his research. His laboratory receives substantial funding, most notably a $3 million award from the Lupus Research Alliance for the TransLuMi project investigating gut pathobiont translocation in systemic lupus erythematosus. As an educator and mentor, Dr. Kriegel directs a substantial research team including multiple postdocs (Drs. Marcia Pereira, Nathalie Becker), PhD candidates (Anna Brinkhege, Carina Brune, Helen Fuhrmann), and laboratory specialists. He participates in the CiM-IMPRS graduate program and supervises medical students through the MedK program. His laboratory currently manages multiple significant research projects including: (A) intestinal wall permeability and pathobiont translocation in autoimmunity; (B) diet-environment-microbiome interactions; (C) microbiota disruption of immunological tolerance; and (D) microbiome roles in lymphoma development. The Kriegel laboratory maintains state-of-the-art facilities at both Münster and Yale, with specialized capabilities in gnotobiotic research, microbiome analysis, and immune profiling. His team collaborates with international partners including Dr. Eran Elinav at Weizmann Institute, Dr. Nissan Yissachar at Bar-Ilan University, Prof. George Tsokos at Harvard, and Prof. Ilana Brito at Cornell University. The laboratory's website (https://www.medizin.uni-muenster.de/mikrobiom/startseite/) details ongoing projects and research opportunities.

Virginia PedicordView profile

Assistant Professor

• Immunology
• Microbiota
• Host-Pathogen Interaction
• +4 more

Dr. Virginia Pedicord is a Principal Investigator at the University of Cambridge's Department of Medicine and the Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID). She leads the Pedicord Lab within the Cambridge Immunology Network as a Sir Henry Dale Fellow, a prestigious research fellowship jointly funded by the Royal Society and Wellcome Trust. Her research focuses on understanding the complex interactions between gut microbiota, host immunity, and disease pathogenesis. Dr. Pedicord received her PhD in Immunology and Microbial Pathogenesis from Cornell University under the supervision of Dr. James P. Allison at Memorial Sloan Kettering Cancer Center, where she studied CD8+ T cell biology. She completed her postdoctoral training at the Rockefeller University before joining the University of Cambridge in 2018. Her laboratory employs a multi-disciplinary approach combining functional metagenomics, in vivo models, cellular immunology, transcriptomics, and proteomics to investigate how commensal microbes influence host intestinal and systemic physiology. Research focuses on gut microbiota's role in immune responses and pathogen resistance Investigates how gut microbes and microbial metabolites affect resistance to infection Studies local and systemic T cell responses and gut-brain axis of neuronal function Uses functional metagenomics to identify cellular and molecular targets of microbiota-mediated immunity Dr. Pedicord's recent publications demonstrate a strong focus on how specific gut bacteria like Enterocloster clostridioformis protect against pathogens such as Salmonella, how microbial metabolites enhance cancer immunotherapy, and the role of the microbiome in various disease contexts including pancreatic cancer and inflammatory bowel disease. Her work bridges fundamental microbiome research with potential therapeutic applications. Scientific Recognition: Sir Henry Dale Fellow (2018) Dr. Pedicord's research program aims to provide mechanistic insights into host-microbiota interactions that will advance our understanding of infectious diseases, autoimmune disorders, and cancer, potentially enabling new therapeutic approaches. Her laboratory is situated at the Jeffrey Cheah Biomedical Centre on the Cambridge Biomedical Campus.

Rinse WeersmaView profile

Professor

• Inflammatory Bowel Disease
• Gut Microbiome
• Crohn's Disease
• +5 more

Professor Rinse Weersma is a Full Professor and Gastroenterologist at the Faculty of Medical Sciences, University of Groningen, and works at the University Medical Center Groningen (UMCG). He leads research in the Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI), focusing on inflammatory bowel diseases and the gut microbiome. Faculty of Medical Sciences, University of Groningen University Medical Center Groningen (UMCG) Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI) Professor Weersma's research primarily centers on inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, with a strong emphasis on understanding the role of the gut microbiome, genetic factors, and immune responses. His work bridges gastroenterology, immunology, and microbiology to develop better diagnostic tools and treatment approaches for IBD patients. He has pioneered research on how diet, environmental factors, and host genetics interact to influence disease development and progression. Analysis of Professor Weersma's recent publications (2025) reveals a strong trend toward multi-omics approaches to understanding inflammatory bowel diseases. His research integrates microbiome analysis, genetic studies, and clinical data to identify biomarkers for disease prediction and treatment response. Key themes include the relationship between gut microbiome composition and IBD, gene-environment interactions, and the application of advanced statistical methods to dietary and clinical data. His work has significant implications for personalized medicine approaches in gastroenterology. Rising Star Award (2011) Professor Weersma actively supervises PhD students including Marjolein Klaassen and Laura Bolte, focusing on gut microbiome research in inflammatory bowel diseases. His research is supported by multiple collaborative projects including the 1000IBD project, which has generated extensive multi-omics data from IBD patients. He frequently collaborates with international research teams across Europe and has contributed to major studies on liver transplantation and microbiome interactions. His work has been funded through various national and international grants supporting gastrointestinal research. Professor Weersma leads research within the Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI), which brings together experts in gastroenterology, immunology, genetics, and microbiome research. His team collaborates extensively through the TransplantLines Investigators consortium and participates in large-scale international research initiatives studying inflammatory bowel diseases across diverse populations.

Gary D. WuView profile

Professor

• Gastroenterology
• Gut Microbiome
• Host-Microbial Interactions
• +4 more

Dr. Gary D. Wu is the Ferdinand G. Weisbrod Professor in Gastroenterology at the University of Pennsylvania’s Perelman School of Medicine, where he serves as Co-Vice Chief for Research in the Department of Medicine and Director of the Penn Center for Nutritional Science and Medicine. He co-leads the Penn-CHOP Microbiome Program and directs multiple NIH-supported core facilities, including the Human-Microbial Analytic and Repository Core (H-MARC) and the Microbial Culture and Metabolomics Core. His research focuses on the interplay between diet, gut microbiota, and host metabolism, with contributions to high-impact journals in microbiome science and clinical gastroenterology. Education : A.B. in Chemistry (Cornell University, 1980); M.D. (Northwestern University Medical School, 1986); Honorary M.A. (University of Pennsylvania, 2002) Research Interests : As a physician-scientist, Dr. Wu investigates how dietary components shape gut microbiome composition and functionality, leading to metabolic and physiological consequences in the host. His work spans translational studies, computational biology, and molecular microbiology, emphasizing microbial metabolism, pathobiont dynamics, and microbiome-driven disease mechanisms. Current projects include dietary interventions for infection resistance and microbiome-based diagnostics for chronic diseases. Publication Trends : Recent articles highlight his expertise in gut microbiome ecology, dietary modulation of pathogens (e.g., Clostridioides difficile ), and host-microbe co-metabolism. Key subfields include nitrogen assimilation, metal availability in early-life microbiomes, and microbiome associations with systemic infections and kidney disease. Scientific Awards : Elected Member of the American Society for Clinical Investigation and the Association of American Physicians; Honorary M.A. from the University of Pennsylvania Labs & Teams : Dr. Wu directs multiple NIH-funded core facilities and co-leads the Penn-CHOP Microbiome Program, fostering collaborations between Perelman School of Medicine and Children’s Hospital of Philadelphia. His lab investigates microbiome-driven pathophysiology, with personnel specializing in molecular microbiology, computational biology, and clinical translational research.

Nagihan BostanciView profile

Professor

• Periodontology
• Inflammation Research
• Cell and Molecular Biology
• +7 more

Prof. Nagihan Bostanci is a Professor of Inflammation Research (Periodontics) and Head of International Affairs at Karolinska Institutet's Department of Dental Medicine. She leads the Master's Degree in Odontology and Oral Health program and holds roles as President of the Microbiology/Immunology Group of the International Association for Dental Research (IADR) and previously served as President of the IADR Periodontal Research Group. Her academic background includes a PhD from the University of London, specialty training at Ege University and UCL, and Habilitation in Oral Biology at the University of Zurich. Research focuses on periodontal homeostasis, inflammatory pathogenesis, and translational approaches for early diagnosis and targeted therapies. Key interests include salivary proteomics, host-microbe interactions, and biomarker discovery. Teaching expertise spans periodontology, diagnostics, and inflammatory pathways at undergraduate and postgraduate levels. She holds certifications in Learning and Teaching (CILT) and is an Associate Fellow of the Higher Education Academy (AFHEA). Major honors include the IADR Sigmund Socransky Young Investigator Award (2014), Philips Oral Healthcare Young Investigator Grant (2009), and Sir Wilfred Fish Prize (2007). Recent grants include Horizon Europe funding for the DELIVER project (€5M) to improve oral care quality and a 2021 award for early tooth loss research. Active in professional leadership, she serves on the editorial board of the Journal of Dental Research and chairs international initiatives in oral microbiology and immunology. Research teams investigate proteome shifts in oral fluids, microbiome dynamics in periodontitis, and clinical applications of biomarkers. Collaborations include studies on peri-implantitis pathogenesis, microbial diagnostics, and the role of intermittent fasting in oral health. Current projects explore aMMP-8 point-of-care testing for disease monitoring and host modulation therapies.

• Gut microbiota
• Mucosal barrier function
• Dietary impact on health
• +5 more

Björn Schröder is an Associate Professor at Umeå University, affiliated with the Department of Molecular Biology and the Laboratory for Molecular Infection Medicine Sweden (MIMS). His research examines how diet, gut microbiota, and mucosal barrier function interact to influence intestinal health, with a focus on Western-style diets, antimicrobial peptides, and protection against infections and inflammation. Current projects include analyzing dietary fiber's role in mucus integrity and linking specific bacteria to barrier function. Primary Affiliation: Department of Molecular Biology, Umeå University Secondary Affiliation: MIMS (Molecular Infection Medicine Sweden) Research interests span gut microbiota, mucosal immunity, antimicrobial peptides, and diet-related pathologies like inflammatory bowel disease and metabolic syndromes. His work combines microbiome analysis with physiological studies in murine models to dissect mechanisms of barrier protection. Recent publications highlight the impact of dietary fiber and probiotics on mucus health, antibiotic effects on barrier integrity, and microbial networks in diseases like colorectal cancer. Themes include diet-microbiota crosstalk, redox regulation of antimicrobial peptides, and microbiota-independent versus dependent mechanisms of mucus damage. Scientific recognition: Fernström Research Prize (2025) Grants: Persson Millions for intestinal research His lab maintains a website at www.mucubacter.org and collaborates with international teams on topics ranging from enteric pathogens to metabolic disease models.

Leo MeileView profile

Professor

• Food Microbiology
• Probiotics
• Fermentation Technology
• +2 more

Leo Meile is an Adjunct Professor at ETH Zurich's Department of Health Sciences and Technology, specializing in food biotechnology. His research encompasses food microbiology, fermentation technology, probiotic safety, and antimicrobial resistance in food systems. Research areas: Microbial ecology of fermented dairy products Biogenic amine formation in fermented foods Antifungal cultures for food preservation He has published extensively on traditional fermentation processes across Africa and Europe and contributed to safety assessments of dairy microorganisms. His work supports the ETH spin-off PharmaBiome.

Yuying XieView profile

Associate Professor

• Single-cell data analyses
• Spatial data analysis
• statistical Machine Learning
• +4 more

Yuying Xie is an Associate Professor holding dual appointments in the Department of Computational Mathematics, Science and Engineering and the Department of Statistics & Probability at Michigan State University. Her research bridges statistical theory, machine learning innovation, and biological discovery, with a focus on developing computational frameworks for high-dimensional biological data analysis. Education: B.S. in Biology, Fudan University, China (2005) Ph.D. in Genetics and Molecular Biology, University of North Carolina at Chapel Hill (2010) Ph.D. in Statistics, University of North Carolina at Chapel Hill (2015) Research Interests: Dr. Xie pioneers methodologies in single-cell data analyses , spatial transcriptomics , and statistical machine learning for biological applications. Her work addresses critical challenges in high-dimensional data analysis through graphical models and QTL/eQTL mapping , with emphasis on biological interpretability and computational efficiency. Current projects integrate deep learning with immunology and cancer biology to decode complex disease mechanisms. Recent Publications: Her 2023-2025 output reveals a strategic focus on transparent single-cell analysis tools (DANCE 2.0), tumor microenvironment modeling (MARVEL, SpatialCTD), and immune-microbiome interactions in disease. Key themes include graph neural networks for spatial data, generative models for biological imaging, and mechanistic studies of immune responses in Crohn's disease, food allergy, and cancer immunology, demonstrating consistent innovation at the statistics-biology interface. Academic Service: Dr. Xie contributes to computational biology through software development (DANCE framework) and large-scale dataset curation (SpatialCTD), enabling reproducible research in immuno-oncology and single-cell genomics.

• Physiology
• Molecular Medicine
• Chronic Diseases
• +3 more

Marcos Fernandez Fondevila is a researcher specializing in Physiology at the Center for Research in Molecular Medicine and Chronic Diseases (CIMUS) within the University of Santiago de Compostela . He is affiliated with the GIBIOMED Biomedical Research Group, focusing on liver diseases and metabolic disorders. Education : PhD in Medicine from the University of Santiago de Compostela (2021), with a thesis on the role of the L-α-lysophosphatidylinositol/GPR55 system in non-alcoholic steatosis and steatohepatitis. Research Interests center on: Molecular mechanisms of steatotic liver disease (NASH/MASLD) Gut microbiota-liver axis interactions Role of protein modifications (e.g., NEDDylation, O-GlcNAcylation) in metabolic regulation Intestinal barrier function in alcohol-related liver disease Signaling pathways in hepatic fibrosis (p63, TLR4, HER2) Neutrophil-mediated inflammation in hepatitis Research Trends from recent publications reveal a focus on alcohol-associated liver disease , metabolic dysregulation , and gut-liver axis dynamics . His work explores NEDDylation in aging, intestinal retroviruses in liver pathology, and microbial metabolites as disease drivers.

Peter D. HigginsView profile

Professor

• Inflammatory Bowel Disease (IBD)
• Gastroenterology
• Molecular Mechanisms of Intestinal Fibrosis
• +4 more

Peter D. Higgins is a Collegiate Professor of Gastroenterology and Professor of Internal Medicine at the University of Michigan Medical School . He completed his MD and PhD in molecular cancer biology at Duke University, followed by a gastroenterology fellowship and MSc in Clinical Research Design at the University of Michigan. AGA IBD Quality Measures Committee member NSAC Chair for Crohn's & Colitis Foundation His research focuses on inflammatory bowel disease (IBD) , particularly intestinal fibrosis and patient-reported outcomes . Current work includes anti-fibrotic therapies , biomarker-guided treatment , and ultrasound-based fibrosis measurement . Recent studies explore JAK inhibitors and sulfidogenic microbes in IBD pathogenesis. Notable Scientific Awards : AGA IBD Clinical Research Excellence Award Dr. Higgins contributes to national IBD care guidelines and serves as the University of Michigan GI Division Research Advisory Council Chair . He is actively involved in the Precision Health Initiative and mentors students in clinical research.

Odile SismeiroView profile

Researcher

• Transcriptomics
• Next-Generation Sequencing (NGS)
• Microbial Genetics
• +3 more

Odile Sismeiro is a Senior Research Engineer at the Transcriptome and Epigenome Platform within the Biomics Pole at the Institut Pasteur . With over three decades of experience, she has been pivotal in advancing RNA sequencing technologies since 2009. Diplôme Universitaire de Technologie Diplôme d’Études Scientifiques et Techniques from CNAM, Paris Her research intertwines Transcriptomics , Microbial Genetics , and Host-Pathogen Interactions , particularly through developing and applying: DNA array technology Next-Generation Sequencing (NGS) RNA-seq data analysis pipelines Key publication themes highlight: Streptococcus pathogenicity networks RNA-based immune sensing mechanisms Vector-borne disease genetics Microbial biofilm regulation She actively contributes to: Scientific training programs Technological development projects Collaborative research across multiple Institut Pasteur units

WanTien ChiangView profile

Assistant Professor

• Systems Immunology
• Bioinformatics
• Computational Biology
• +6 more

WanTien (Austin) Chiang is an Assistant Professor at the Medical College of Georgia , Augusta University, affiliated with both the Department of Medicine and the Immunology Center of Georgia . With expertise spanning systems immunology, bioinformatics, and computational biology, Dr. Chiang develops biological modeling algorithms to study complex immunological systems and human diseases.