Find Academic Supervisors

• Nanomedicine
• Theranostics
• Drug Delivery Systems
• +5 more

Twan Lammers is a full Professor of Medicine at the Institute for Experimental Molecular Imaging (ExMI) within RWTH Aachen University Clinic. He leads the Nanomedicine and Theranostics research group focused on developing image-guided drug delivery systems for cancer and fibrotic diseases. Research Focus: His work centers on nanomedicine tumor targeting , combining drug delivery with molecular imaging to monitor tumor growth, angiogenesis, inflammation, and metastasis. Key areas include engineering polymeric microbubbles for ultrasound-mediated drug delivery, optimizing nanoparticle biodistribution using EPR and ATR mechanisms, and developing clinical translation frameworks for nanotherapeutics. His group pioneered transferrin receptor-targeted microbubbles for blood-brain barrier sonopermeation and desmoplastic tumor priming strategies using corticosteroid liposomes. Awards & Recognition: ERC Starting and Consolidator Grants Controlled Release Society Young Investigator Award (2015) Clarivate Highly Cited Researcher (since 2019) Over 250 publications with significant clinical impact Leadership: Serves as handling editor for Journal of Controlled Release and Molecular Imaging and Biology , and chairs special issues on stimuli-responsive nanotheranostics. His research bridges preclinical innovation with clinical applications through collaborations with pharmaceutical partners and clinical trial networks.

• Organic Chemistry
• Medicinal Chemistry
• Drug Discovery
• +7 more

Dr. Fabrizio Pertusati is a Lecturer at the School of Chemistry, Cardiff University, with expertise in organic and medicinal chemistry. He holds an MSc in Physical Organic Chemistry from the University of Turin and a PhD in asymmetric organic chemistry from Cardiff School of Chemistry. His academic journey includes postdoctoral training at Emory University and in the laboratory of Nobel laureate Prof. George Olah at the University of Southern California. Dr. Pertusati's research focuses on the design and synthesis of small molecules as therapeutics against rare diseases (including congenital disorder of glycosylation, Niemann-Pick, Cystinosis, and GNE myopathy), infectious diseases, and antifungal drug discovery. His key expertise areas include organofluorine chemistry, organophosphorus chemistry, carbohydrate chemistry, and the design and synthesis of phosphate/phosphonate prodrugs of carbohydrate scaffolds. His recent publications demonstrate a strong focus on nucleoside prodrug technologies (particularly ProTide technology), with applications in antiviral therapy, anticancer agents, and treatment of rare metabolic disorders. His work often involves interdisciplinary collaborations with researchers specializing in lysosomal storage diseases, biofilm formation, and antimicrobial resistance. Dr. Pertusati serves as a reviewer for numerous prestigious journals including Journal of Medicinal Chemistry, European Journal of Medicinal Chemistry, and Organic Letters. He has also been a reviewer for MRC-fellowship grants and was a member of the Scientific Advisory Board of Ichorion Therapeutics (2017-2018). His teaching portfolio includes courses on industrial applications of biocatalysis, techniques in drug discovery, drug targets, drug development from laboratory to clinic, and introduction to drug development.

• Nanophysics
• Condensed-matter physics
• Semiconductor nanomaterials
• +6 more

Valeriy Skryshevsky is Professor and Head of the Chair of Nanophysics of Condensed Matters at the Faculty of Physics, Taras Shevchenko National University of Kyiv, Ukraine . Since 1981 he has advanced from Scientific Researcher to full Professor and Chair, with visiting appointments at Ecole Centrale de Lyon and INSA de Lyon (1997-1998) and Comenius University (1989). Education M.Sc. in Physics, Taras Shevchenko National University of Kyiv (1978) Candidate of Phys.-Math. Sciences (Ph.D.), Taras Shevchenko National University of Kyiv (1984) Doctor of Physical and Mathematical Sciences, Taras Shevchenko National University of Kyiv (2001) Research interests lie at the intersection of nanophysics, condensed-matter physics and optoelectronics . His early work focused on improving the efficiency of silicon solar cells using porous and nanostructured materials. He then pioneered the theory and application of chemical sensors based on metal–nanocrystalline-silicon heterostructures , enabling detection of hydrogen, moisture, hydrocarbons, heavy metals and organic compounds. Presently his group develops third-generation silicon solar cells (including Bragg mirrors and photoluminescent concentrators), electronic tongue systems for rapid liquid/gas recognition via photovoltaic transducers, and silicon and silicon-carbide quantum dots for bio-imaging and drug delivery. His publication portfolio (1996–2016) reveals sustained investigation into porous-silicon photoluminescence, surface-state physics, photovoltaic structures, hydrogen storage, and nanomaterial–biological interfaces . The trend shows a progression from fundamental studies of porous-silicon optical and electrical properties to highly applied sensor and energy-harvesting devices, culminating in multifunctional quantum-dot platforms for theranostics. Scientific awards State Prize in Science and Technology of Ukraine (2012) Honored Worker of Science and Technique of Ukraine (2016) Grants & Projects include coordination of the EU TEMPUS project “Curricula Development for Master of Microsystems Design” (2012-2016) and the H2020-MSCA-RISE project “Carbon-based nano-materials for theranostic application (CARTHER)” (2016-2019). Laboratory & Facilities – He heads the Chair of Nanophysics of Condensed Matters and previously led a research laboratory equipped with SEM, AFM, optical spectroscopy, PL, FTIR and custom photovoltaic and sensor characterization setups.

• Molecular Imaging
• Imaging Physics
• Image Reconstruction
• +7 more

Chin-Tu Chen is a Professor in the Department of Radiology-Basic Sciences at the University of Chicago. His research focuses on integrative multi-modality molecular imaging with applications across cancer, brain disorders, cardiopulmonary diseases, and diabetes. Dr. Chen has maintained continuous NIH funding for over three decades, demonstrating significant contributions to medical imaging physics and technology development. Dr. Chen's educational background includes: BS in Physics from National Tsing-Hua University, Taiwan (1974) MS in Physics from Northwestern University (1978) PhD in Medical Physics from The University of Chicago (1986) His research spans imaging physics and instrumentation, image reconstruction algorithms, tracer development, physiological modeling, and quantitative image analysis. Dr. Chen's integrative approach combines multiple imaging modalities to address complex biomedical questions, with particular emphasis on translating basic imaging advances into clinical applications for disease diagnosis and treatment monitoring. Analysis of Dr. Chen's publication record reveals sustained innovation in molecular imaging technologies, with increasing focus on multimodal approaches combining PET, SPECT, and MR imaging. His work demonstrates strong interdisciplinary collaboration across oncology, neuroscience, and cardiopulmonary medicine, with growing integration of nanotechnology for targeted imaging and therapy applications. Dr. Chen's research impact is evident through numerous highly-cited publications and sustained NIH funding: Multiple publications with over 100 citations Continuous NIH funding since the 1990s Significant contributions to imaging technology standards As Principal or Co-Principal Investigator on multiple NIH grants including R01CA297777 on neural stem cell tracking for brain metastases and R01CA236385 on improved radiation therapy through integrated imaging, Dr. Chen maintains an active research program with substantial collaborative networks across departments and institutions. His current work emphasizes translational applications of advanced imaging technologies for personalized medicine approaches. Dr. Chen leads a research program focused on integrating preclinical and translational imaging resources, with particular expertise in developing novel imaging instrumentation and methodologies. His laboratory work bridges fundamental physics with clinical applications, maintaining strong collaborations with oncology, neuroscience, and cardiopulmonary research teams to address critical diagnostic and therapeutic challenges.

Renato Emanuel Felix BotoView profile

Associate Professor

• Organic Chemistry
• Medicinal Chemistry
• Photodynamic Therapy
• +4 more

Renato Emanuel Félix Boto is an Associate Professor at the Department of Chemistry, University of Beira Interior (UBI), Portugal. He is also a vice-coordinator of the Biopharmaceuticals and Biomaterials Research Group (BB) within the Health Sciences Research Centre (CICS-UBI). His academic career spans over 25 years, with teaching responsibilities in Organic Chemistry. Graduated in Analytical Chemistry (1993) from University of Aveiro PhD in Chemistry (2007) from University of Beira Interior Provas de Aptidão Pedagógica e Capacidade Científica (1999) equivalent to MSc Dr. Boto's research focuses on synthesizing functional cyanine dyes for biomedical applications, including photodynamic therapy (PDT) , fluorescent probes , and chromatographic ligands for protein/DNA separation. His work bridges organic synthesis with therapeutic development and analytical chemistry applications. Recent trends in his publications emphasize indolenine-based squaraine dyes for cancer treatment, antifungal agents , and albumin detection probes . He has contributed to optimizing synthetic methodologies for barbiturate-coupled dyes and benzisoxazole derivatives . He has supervised 6 MSc students and co-supervised 3 others, while contributing to 5 research projects including: UID/Multi/00709/2019 (completed) CENTRO-45-2018-10 (ongoing) CENTRO-01-0145-FEDER-000013 (completed) Dr. Boto co-authored over 30 peer-reviewed articles with 259 citations and participated in numerous national/international scientific meetings.

• Protein Folding
• Neurodegenerative Diseases
• Biochemistry
• +5 more

Jill Zitzewitz is an Associate Professor at UMass Chan Medical School , with affiliations in the Department of Radiology , Biochemistry and Molecular Biotechnology , Neurology , and NeuroNexus Institute . She also holds positions in graduate programs including the Morningside Graduate School of Biomedical Sciences in Biochemistry and Molecular Biotechnology , Neuroscience , and Translational Science . Education : B.A. in Chemistry from Carthage College (1986) PhD in Bioorganic Chemistry from Washington University in St. Louis (1991) Postdoctoral training in Protein Folding at Pennsylvania State University with an NIH Fellowship Research interests focus on protein misfolding and its role in neurodegenerative diseases , particularly amyotrophic lateral sclerosis (ALS) . Her work investigates molecular interactions stabilizing native protein conformations and develops biophysical methods to probe folding, misfolding, and aggregation of ALS-linked proteins like SOD1 and TDP-43 . This includes thermodynamic analyses and applications of mass spectrometry and fluorescence anisotropy to study structural rearrangements and stability cores. Publications highlight trends in protein folding dynamics , ALS pathogenesis , and structural biology . Key subfields include conformational transitions , hydrophobic interactions , RNA-binding proteins , and therapeutic development for neurodegenerative disorders. Collaborative Networks include co-authors such as Francesca Massi , Daryl Bosco , and John Landers . She is part of teams in Translational Anatomy and NeuroNexus Institute , with physical neighbors like Andreas Bergmann and Daniel Caffrey .

• Cancer Pharmacology
• Enzyme Activity Imaging
• Drug Response Modeling
• +3 more

Sampreeti Jena is a Researcher in the Department of Experimental and Clinical Pharmacology at the University of Minnesota. Her work focuses on cancer pharmacology, enzyme activity imaging, and computational drug discovery, particularly for castration-resistant prostate cancer and pediatric central nervous system tumors. Institution: University of Minnesota Department: Experimental and Clinical Pharmacology Her research interests include: Using single-cell transcriptomics and pan-cancer analysis to identify therapeutic vulnerabilities in heterogeneous tumors Developing fluorescence lifetime imaging (FLIM) probes for kinase activity measurement Investigating protein stability in pharmaceutical formulations Creating computational models for drug response prediction Recent publications highlight her contributions to precision oncology through: Digital tumor modeling for therapeutic inference Identification of pan-histology immunomodulatory targets Advancements in FLIM probe technology Excipient interaction studies affecting protein stability Current projects include: Dynamic Digital Tumors for Precision Oncology (University of California San Diego, 2024-2025) Genetic mechanisms underlying sexual dimorphism in cancer (University of Colorado & NIH, 2024-2026)

Markita LandryView profile

Associate Professor

• Nanomaterials
• Fluorescence Microscopy
• Sensors
• +3 more

Markita Landry is an Associate Professor of Chemical and Biomolecular Engineering at the University of California, Berkeley, affiliated with the College of Engineering. Her research spans interdisciplinary applications of nanotechnology in neuroscience and plant engineering. 2022: Chan-Zuckerberg Biohub Young Investigator, Vilcek Prize for Creative Promise 2021: National Academies Committee member, Dreyfus Teacher-Scholar Award 2020: NSF CAREER Award, CZI Deep Tissue Imaging Award 2019: Bakar Fellow, Sloan Foundation Fellow Research Interests: The Landry Lab focuses on synthetic bio-mimetic nanocomposites for Molecular Imaging and Targeted Bio-Delivery . In neuroscience, they engineer optical probes for neuromodulators like dopamine and serotonin to study disorders such as addiction, Huntington's, and Parkinson's. In plant engineering, they develop nanoparticle platforms for DNA/RNA delivery to crops (e.g., wheat, cotton) without transgene integration, aiming to enhance yield, stress tolerance, and regulatory compliance for GMO alternatives. Publication Trends: Her recent work highlights nanomaterials in in vivo neurotransmitter monitoring and plant genetic engineering. Key themes include CRISPR-compatible delivery systems, non-invasive RNA/DNA vectors, and infrared fluorescence for disease modeling. Scientific Awards: 2022 Vilcek Prize for Creative Promise in Biomedical Science 2020 NSF CAREER Award 2019 Bakar Fellow 2018 DARPA Young Faculty Award 2017 Kavli Fellow (National Academies of Engineering) Labs & Teams: The Landry Lab at UC Berkeley pioneers synthetic nanocomposites for biomedical and agricultural applications. Their collaborative work bridges the interface of materials science, neuroscience, and plant biotechnology, supported by grants from organizations like the Chan-Zuckerberg Biohub and the Dreyfus Foundation.

Yamuna KrishnanView profile

Professor

• Biochemistry
• Molecular Biology
• Cellular Biology
• +4 more

Yamuna Krishnan is a Professor in the Department of Chemistry at the University of Chicago. Her research focuses on developing DNA nanodevices for quantitative chemical imaging of organelles , particularly mapping ion dynamics in lysosomes and acidic organelles. Key Contributions: Solved a 30-year problem in molecular sensing by quantifying lumenal calcium in acidic organelles, identifying the first human lysosomal Ca²⁺ importer . Publications highlight her work in DNA-based fluorescent probes , lysosomal function , and tumor targeting via macrophage modulation . Her technology enables studies in live multicellular organisms and human patient cells . Recent articles: Acc. Chem. Res. (2024), Nat. Methods (2019), Nat. Nanotechnol. (2021), Sci. Adv. (2024). She actively collaborates with institutions like the Institut Pasteur, delivering seminars on Intracellular Electrophysiology in 2025.

• Regenerative Medicine
• Tissue Repair
• Skeletal System
• +5 more

Meriem Lamghari is a full Professor at the Institute of Biomedical Sciences Abel Salazar, University of Porto, Portugal. She leads the NeuroSkeletal Circuits (NESK) research group at INEB/i3S, focusing on neuro-skeletal interactions, tissue engineering, and regenerative medicine. She received her Ph.D. in Osteoarticular Biology, Biomechanics and Biomaterials from Université Jussieu Paris 7 in 1999. Established research line on neuro-skeletal interactions in 2009 Coordinated H2020 RESTORE project on smart nanobiomaterials Partner in FLAMIN-GO, sinPain, PREMUROSA, and BonePain EU projects Her research bridges neuroscience and skeletal biology, using microfluidic platforms to study neuro-immune interactions in osteoarthritis, bone metastasis, and tissue regeneration. She has secured extensive national and international funding, including multiple Horizon 2020 and MSCA grants. Recent publications highlight her work on neuro-immune interplay in joint pain, 4D bioprinting for cartilage repair, and metastasis-on-chip systems. Her lab develops innovative approaches to bone regeneration involving nanobiomaterials and sympathetic nervous system modulation .

Kirsten KnoxView profile

Lecturer

• Plant Transport Mechanisms
• Molecular Biology
• Cell Biology
• +4 more

Kirsten Knox is a Lecturer in Molecular Biosciences at the School of Life Sciences, University of Glasgow. She received her BSc in Genetics and Immunology from the University of Aberdeen and a PhD from the University of York under Dame Professor Ottoline Leyser. Education: BSc (Aberdeen), PhD (York) Research Focus: Plant transport mechanisms, plasmodesmata dynamics, phloem function, and circadian regulation Teaching: Course Coordinator for Level 2 Genes, Molecules and Cells and Level 3 Biochemistry

Jacques LuxView profile

Researcher

• Theranostics
• Nanomedicine
• Ultrasound Imaging
• +12 more

Jacques Lux is a researcher in the Department of Radiology at the University of Texas Southwestern Medical Center, where he contributes to the Translational Research in Ultrasound Theranostics (TRUST) program. His work bridges chemistry, materials science, and biomedical imaging, with a focus on developing next-generation diagnostic and therapeutic agents. Education: PhD in Chemistry, University of Strasbourg, under Nobel laureate Jean-Pierre Sauvage Postdoctoral training at Faculty of Pharmacy, Strasbourg Postdoctoral research at Scripps Research Institute (La Jolla, CA) Postdoctoral and Research Scientist roles at UCSD Dr. Lux's research focuses on theranostics , particularly the design of activatable ultrasound agents that enable both cancer detection and targeted therapy through drug release or high-intensity focused ultrasound. His work also encompasses stimuli-responsive nanomaterials , including light- and enzyme-activatable systems, and the development of high-relaxivity MRI contrast agents using nanogel platforms. These efforts aim to improve imaging specificity, reduce toxicity, and enable image-guided interventions. The 15 most recent publications highlight a strong trend in multimodal imaging , nanoparticle engineering , and translational biomedical applications . Key themes include ultrasound-triggered therapies, oxygen-generating nanoparticles for hypoxia relief, biosensors for infection detection, and light-responsive drug delivery systems. The research integrates supramolecular chemistry, polymer science, and clinical imaging to create smart, responsive platforms for precision medicine. Scientific Awards: No awards explicitly mentioned in the provided text. Dr. Lux has been actively involved in research grants and collaborative projects, particularly in the development of nanoparticle-based theranostic systems and image-guided cancer therapies . His collaborations span chemistry, radiology, and bioengineering, often involving translational studies aimed at clinical application. He has contributed to the design of novel contrast agents, enzyme-loaded nanoparticles, and activatable probes, suggesting sustained funding from biomedical research agencies. He is a key member of the TRUST program at UT Southwestern, a multidisciplinary team focused on advancing ultrasound theranostics. His lab likely involves a team of postdoctoral researchers, graduate students, and engineers working on nanoparticle synthesis, in vivo imaging, and preclinical validation of novel agents. The emphasis on translational research indicates strong institutional and possibly industry partnerships.

Ian LipscombView profile

Senior Lecturer

• Medical Applications
• Biomechanics
• Prion Research
• +4 more

Ian Lipscomb is the Head of Engineering and Computing at the University of Chichester, with a PhD in mathematical modeling of knee joint injuries from Cardiff University. He has over 10 years of teaching experience across Higher, Further, and Private educational institutions, including leadership roles in two Colleges. His research spans biomedical applications of shape memory metals, prion contamination prevention on surgical instruments, and flipped learning methodologies in education. BEng (Hons), PhD, DTLLS, QTLS Fellow of the Institute of Mathematics and its Applications (FIMA) Fellow of the Royal Statistical Society (FRSS) Fellow of the Higher Education Academy (FHEA) His work focuses on prion research , piezoelectric materials , and biomedical engineering , with a recent book on shape memory metals in medicine. Publications include collaborations with Southampton and Keevil on surgical steel contamination and ceramic breakdown mechanisms. Scientific awards include fellowships in FIMA, FRSS, and FHEA, reflecting his contributions to mathematics, statistics, and education. He has developed protocols for protein contamination detection and investigated electrical breakdown in ceramics under environmental stressors. Ian's research on flipped learning and surgical hygiene has led to 10+ publications, emphasizing interdisciplinary applications in medical physics and materials science. His academic journey includes postdoctoral research on human prion diseases and engineering education innovation.

• Cell Biology
• Biochemistry
• Chemistry
• +7 more

Hyunil Jo, PhD is a Specialist in the School of Pharmacy at the University of California, San Francisco (UCSF) . His research focuses on integrin signaling, protein design, and therapeutic targeting of disease mechanisms such as hepatic fibrosis and neurodegenerative disorders. Education: BS (2001) and MS (2003) in Pharmacy, Seoul National University PhD (2008) in Chemistry, University of Pennsylvania Research Interests: Integrin biology dominates his work, with studies on α2β1 and α5β1 integrins in airway disease, renal fibrosis, and vascular smooth muscle function. He also pioneers de novo protein design for drug-binding specificity and uses biophysical probes (e.g., fluorescent amino acids, infrared spectroscopy) to study protein structure and dynamics. His virology work includes SARS-CoV-2 envelope protein analysis, while earlier projects explored malaria and amyloid fibril formation. Publications (2025-2010): His 35+ publications span integrin-mediated diseases, custom protein engineering, and structural studies of amyloid and viral proteins. Key journals include Science , Nature Chemical Biology , PNAS , and Cell . Awards: Department of Defense Predoctoral Training Award for Prostate Cancer (2005-2008) Grants: Principal Investigator, NIH/NIDDK R01DK137892 (2023-2028) - Targeting Acid Ceramidase for Hepatic Fibrogenesis Co-Principal Investigator, NIH R61HL163725 (2022-2024) - Mitigation of Smooth Muscle Force via Integrin Alpha2Beta1 Inhibitors Collaborations: Work with William DeGrado (UCSF) on protein engineering Collaborations with Dean Sheppard (UCSF) in integrin research Partnerships in vaccine development and virology projects

Steven MagennisView profile

Professor

• Physical Chemistry
• Single-Molecule Fluorescence Spectroscopy
• DNA Structure & Dynamics
• +3 more

Dr. Steven Magennis is a Professor in Physical Chemistry at the School of Chemistry , University of Glasgow. His research focuses on single-molecule fluorescence techniques to study DNA structure, dynamics, and reactivity. Key Research Areas : Physical Chemistry, Biochemistry, DNA Structural Biology Institution : University of Glasgow, UK His work leverages fluorescent nucleobase analogs , two-photon excitation , and single-molecule FRET to unravel DNA conformational changes and interactions. Recent studies include metallation effects on DNA dynamics and trinucleotide repeat behavior . Selected trends from 15 most recent articles highlight expertise in fluorescent probe development , DNA junction analysis , and optical detection methods . Collaborations span institutions in the UK and beyond.