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Britt AdamsonView profile

Associate Professor

• Stress Response Networks
• DNA Damage Response
• Genome Editing
• +3 more

Britt Adamson is an Associate Professor in the Department of Molecular Biology and the Lewis-Sigler Institute for Integrative Genomics at Princeton University, where she serves as Director of the Undergraduate Program in Quantitative and Computational Biology. Her lab investigates molecular networks in human cells with focus on stress response mechanisms and genome editing technologies. She received her B.S. in Biology from the Massachusetts Institute of Technology (2005) and Ph.D. in Genetics and Genomics from Harvard University (2012), followed by postdoctoral training at UCSF under Jonathan Weissman supported by a Damon Runyon Cancer Research Foundation Fellowship. Adamson's research centers on how cells organize stress response networks during DNA damage and endoplasmic reticulum stress, developing CRISPR-based functional genomics and single-cell sequencing tools to map molecular behaviors. Her work bridges fundamental cell biology with therapeutic applications in genome editing. Analysis of her 15 most recent publications reveals dominant themes in precision genome editing (prime/base editing optimization) and systematic dissection of DNA repair pathways through combinatorial CRISPR screening. Her lab consistently integrates computational approaches with high-resolution experimental techniques to uncover context-dependent cellular behaviors. Her scientific recognitions include: Damon Runyon Cancer Research Foundation Postdoctoral Fellowship Princeton IP Accelerator Award (2025) STAT Who to Know: 10 Scientists leading a new generation of gene editors (2024) Adamson actively mentors eight graduate students (including alumni Ann Cirincione and Jun Hussmann) and two postdocs, with research funded through institutional awards and collaborative grants. Her lab's technological developments have enabled projects spanning virology, immunology, and developmental biology. The Adamson Lab operates within Princeton's Lewis-Sigler Institute for Integrative Genomics, fostering an interdisciplinary environment that merges cell biology, genomics, and computational science. Current projects focus on improving prime editing efficiency and understanding stress response adaptation in disease contexts.

Zhe JiView profile

Assistant Professor

• Data Science
• Computational Biology
• Functional Genomics
• +4 more

Zhe Ji is an Assistant Professor in the Department of Biomedical Engineering at McCormick School of Engineering and the Department of Pharmacology at Feinberg School of Medicine, Northwestern University. His research integrates computational and experimental genomics to study gene transcription and RNA translation in cell fate commitment and oncogenic processes, aiming to develop precision medicine strategies. **Education**: Postdoctoral Fellow in Cancer Systems Biology, Harvard Medical School Postdoctoral Fellow in Computational Biology, Broad Institute of MIT and Harvard Ph.D. in Computational Genomics, Rutgers University B.S. in Biotechnology, Nanjing University, China **Research Focus**: Keywords include Data Science, Computational Biology, Functional Genomics, RNA, Cancer, Inflammation, and Machine Learning. The lab explores regulatory mechanisms underlying disease, with a focus on translational control, cancer metastasis, and inflammatory networks. **Grants & Advising**: No specific grants or student advisees listed. The lab emphasizes collaborative projects and computational-experimental approaches. **Lab Affiliations**: Zhe Ji’s lab is part of Northwestern’s interdisciplinary environment, bridging engineering and medicine to advance genomic technologies and therapeutic strategies.

• Cancer Biology
• Mathematical and Computational Modeling
• Bioinformatics
• +7 more

Dana Pe'er is a Professor and Chair of the Computational and Systems Biology Program at the Sloan Kettering Institute (SKI) of Memorial Sloan Kettering Cancer Center. She is also an Investigator of the Howard Hughes Medical Institute and holds the Alan and Sandra Gerry Endowed Chair. Dr. Pe'er leads an interdisciplinary research group that combines advanced genomics approaches with machine learning to address fundamental questions in biomedical science, with particular focus on cancer biology, developmental biology, and immunology. Dr. Pe'er earned her PhD from Hebrew University in Jerusalem, Israel. Her academic journey includes a postdoctoral fellowship with George Church at Harvard Medical School. Before joining Memorial Sloan Kettering Cancer Center in 2016, she held faculty positions at Columbia University. Dr. Pe'er's research focuses on understanding cellular plasticity, the consequences of intra-tumor heterogeneity, cancer evolution and metastasis, and the mechanisms by which regulatory circuits go awry in disease. Her lab combines single-cell and spatial profiling technologies with machine learning approaches to investigate gene regulation, cellular plasticity, and cell-cell communication in the contexts of cancer, immunity, and development. They are particularly interested in how organisms develop from a single cell to generate diverse cell types, how epigenetic control rewires during development, and how cells communicate to execute multicellular responses. Analysis of Dr. Pe'er's recent publications reveals a strong focus on developing computational methods for single-cell and spatial genomics data analysis. Her work spans cancer types including pancreatic, prostate, colorectal, and breast cancer, with emphasis on tumor heterogeneity, metastasis mechanisms, and cellular plasticity. A significant portion of her research involves creating novel algorithms and tools like CellRank, REUNION, and SEACells that enable researchers to extract meaningful biological insights from complex genomic datasets. 2023 Class of 2023 Inductee - American Academy of Cancer Research (AACR) Academy 2023 Innovator Award - International Society for Computational Biology (ISCB) 2021 Fellow - International Society for Computational Biology (ISCB) Howard Hughes Medical Institute Investigator (2021) 2019 Ernst W. Bertner Memorial Award - University of Texas MD Anderson Cancer Center 2016 Lenfest Distinguished Faculty Award - Columbia University 2014 Director's Pioneer Award - National Institutes of Health 2014 Overton Prize - International Society for Computational Biology (ISCB) Dr. Pe'er is known for her dedicated mentorship approach, describing herself as "a mama bear" who cares deeply about her trainees while expecting independence, innovation, and hard work. She mentors numerous PhD students and postdocs in her lab. Her HHMI Investigator award provides approximately $9 million over seven years, enabling ambitious research directions. She also collaborates extensively with the Single-cell Analytics and Innovation Lab (SAIL) at MSK to generate new data from emerging technologies, working closely with wet-lab collaborators at MSK and beyond to apply computational methods to cutting-edge datasets across multiple disease areas. The Pe'er Lab is an interdisciplinary group of computational biologists with diverse backgrounds ranging from pure mathematics to clinical medicine. They work closely with wet-lab collaborators to apply their computational methods to cutting-edge datasets across cancer, immunology, and developmental biology. The lab is described as open, supportive, collaborative, and fun, with access to world-class facilities at the Sloan Kettering Institute. Dr. Pe'er's work continues to push the boundaries of computational biology and cancer research, with the ultimate goal of developing more effective, personalized therapies for cancer patients.

Silvia ArberView profile

Professor

• Molecular and cellular mechanisms of neuronal differentiation
• Neuronal circuit development and connectivity
• Motor system development and function
• +7 more

Silvia Arber holds a joint appointment as Full Professor for Neurobiology/Cell Biology at the Biozentrum, University of Basel, and serves as Senior Group Leader at the Friedrich Miescher Institute (FMI) in Basel, Switzerland. Her laboratory investigates the organization, function, and development of neuronal circuits controlling motor behavior, with a particular focus on how these circuits enable precise movement control. Arber obtained her PhD in 1996 from the Friedrich Miescher Institute under Pico Caroni, followed by postdoctoral training with Thomas Jessell at Columbia University (1996-2000), where she studied transcription factors in spinal cord neuronal differentiation. Her educational background includes Biology II studies at the Biozentrum of the University of Basel with graduation in Cell Biology (1987), a diploma thesis at the FMI (1990), and graduate work at the FMI (1992). Her research program centers on elucidating how neuronal circuits orchestrate accurate motor behavior in response to sensory cues and voluntary movement initiation. Using mouse as a model system, her laboratory employs multi-faceted approaches including advanced mouse genetics, viral technologies for transsynaptic circuit tracing, optogenetics and pharmacogenetics for functional manipulation, quantitative behavioral analysis, electrophysiology, and gene expression profiling. Her work has revealed precise synaptic interactions within dedicated motor circuit modules throughout the nervous system and how these impact function, with implications for understanding diseases causing motor deficits and spinal cord injury. Analysis of Arber's publication record shows a consistent focus on motor circuit organization, with particular emphasis on transcriptional control mechanisms, circuit connectivity mapping, and the relationship between developmental processes and functional circuit organization. Her work bridges molecular, cellular, and systems neuroscience, providing fundamental insights into how the nervous system controls movement. The Brain Prize (2022) Elected to the National Academy of Sciences of the United States (2020) Physiological Society Annual Review Prize Lecture (2019) Pradel Research Award (2018) W. Alden Spencer Award (2018) Louis-Jeantet Prize for Medicine (2017) ERC Advanced Grant (2010-2015) EMBO Member (2005) EMBO Young Investigator Award (2001) While specific students are not listed in the provided materials, Arber's laboratory has received significant research funding including an ERC Advanced Grant (2010-2015) and multiple prestigious awards supporting her research program. Her laboratory at the Biozentrum (Room 11.038) collaborates closely with the Friedrich Miescher Institute, where she serves as Senior Group Leader. The research group employs cutting-edge technologies for neural circuit analysis and has contributed fundamental insights into motor circuit organization, with implications for understanding and potentially treating movement disorders and spinal cord injuries.

Benjamin SimonsView profile

Professor

• Stem Cell Biology
• Developmental Biology
• Cancer Biology
• +3 more

Benjamin Simons is the Royal Society EP Abraham Professor and Herchel Smith Professor of Physics at the University of Cambridge. He serves as Director of the Gurdon Institute, Senior Group Leader at the Gurdon Institute, Principal Investigator at the Cambridge Stem Cell Institute, and member of the Theory of Condensed Matter physics group. He is also a Fellow of St. John's College, Cambridge. His research integrates quantitative approaches from physics and mathematics with experimental biology to investigate stem cell fate regulation in tissue development, maintenance, and cancer pathogenesis. Research focuses on: Stochastic cell fate decisions in epithelial tissues Self-organization principles in tissue morphogenesis Single-cell lineage tracing and gene expression analysis Mathematical modeling of stem cell dynamics Cancer initiation through stem cell reprogramming Publication analysis reveals consistent themes: spatial dynamics of stem cell niches, mechanical regulation of cell fate, computational modeling of tissue organization, and evolutionary principles in cancer development. Recent work emphasizes in vivo lineage tracing, single-cell omics, and interdisciplinary approaches bridging physics and biology. Scientific Awards: Fellow of the Royal Society (FRS) Fellow of the Academy of Medical Sciences (FMedSci) Leads an interdisciplinary research group combining wet-lab experiments (lineage tracing, single-cell genomics) with theoretical modeling. Research supported by EPSRC, MRC, Wellcome Trust, Cancer Research UK, and Royal Society grants. Current projects include gliomagenesis mechanisms, spermatogenic wave regulation, and injury response pathways co-opted in cancer.

Ashley MosemanView profile

Assistant Professor

• CNS immunity
• Olfactory barrier immunology
• Neuroimmunology
• +5 more

Ashley Moseman serves as an Assistant Professor of Integrative Immunobiology and Assistant Professor of Cell Biology at Duke University School of Medicine. She holds significant affiliations as a Faculty Network Member of the Duke Institute for Brain Sciences and a Member of the Duke Cancer Institute. Her pioneering research examines the delicate balance between neuronal function and immune protection at the olfactory neuroepithelial barrier, where sensory neurons directly interface with the external environment while protecting the central nervous system from pathogens. Dr. Moseman completed her Ph.D. at Harvard University in 2011, establishing the foundation for her interdisciplinary career at the intersection of immunology and neuroscience. Her research program focuses on understanding how immunological surveillance operates at the unique olfactory barrier, where neurons must contact the external environment to perform chemosensory functions while preventing pathogens from entering the CNS. The Moseman Lab employs cutting-edge multiphoton intravital imaging to visualize immune responses in vivo, revealing dynamic cellular interactions during viral infections and responses to pathogens like Naegleria fowleri. Current projects investigate olfactory barrier mechanisms, neuroimmune crosstalk, host-pathogen dynamics, and immune responses to deadly neurotropic pathogens. Analysis of Dr. Moseman's publication record demonstrates a cohesive research trajectory centered on neuroimmunology and mucosal defense mechanisms. Her work spans fundamental immunological processes, host-pathogen interactions at neural interfaces, and translational applications for understanding neurological complications of infections. A significant portion of her recent research addresses SARS-CoV-2-related olfactory dysfunction and the immunological basis of pathogen invasion through the olfactory system into the central nervous system. Dr. Moseman has secured substantial research funding including 'Using tissue-specific Naegleria opportunism to dissect olfactory immunity' (2025-2030), 'Characterizing olfactory plasma cell dynamics and survival niche within the upper airway' (2024-2029), and the 'Advanced Immunobiology Training Program for Surgeons' (2019-2029). She actively contributes to graduate education through the Medical Scientist Training Program (2022-2027) and teaches advanced immunology courses including IMMUNOL 736 and IMMUNOL 494. The Moseman Lab represents a leading center for neuroimmunology research, utilizing in vivo imaging to visualize immune responses within the central nervous system. Their work has significant implications for understanding how pathogens breach neurological barriers and how the immune system protects the brain while preserving essential sensory functions, with potential applications for treating neurological infections and inflammatory conditions.

Jonathan WeissmanView profile

Professor

• Protein Folding
• Systems Biology
• Genomics
• +6 more

Jonathan Weissman is a Professor of Biology at the Massachusetts Institute of Technology (MIT) and a Member of the Whitehead Institute. He is also an Investigator of the Howard Hughes Medical Institute and the Landon T. Clay Professor of Biology. His research spans protein folding mechanisms, ribosome profiling, CRISPR-based tools (CRISPRi/a), and genetic interaction mapping. Whitehead Institute Member MIT Professor HHMI Investigator Co-founder, Maze Therapeutics & KSQ Therapeutics Research Interests focus on: Protein folding in cellular contexts Endoplasmic reticulum (ER) function and stress responses Genome-wide CRISPR screening for gene regulation High-density genetic interaction maps in mammals Mitochondrial protein targeting and quality control Epigenomic engineering with synthetic tools Scientific Awards include: Protein Society Irving Sigal Young Investigator Award (2004) Raymond & Beverly Sackler Prize (2008) National Academy of Sciences election (2009) NAS Award for Scientific Discovery (2015) Genetics Society of America Ira Herskowitz Award (2020) Labs & Collaborations : Leads the Weissman Lab at MIT/Whitehead Institute, co-leads the Laboratory for Genomic Research with GlaxoSmithKline, and chairs the Stowers Institute Scientific Advisory Board.

Jun WuView profile

Assistant Professor

• Stem Cell Biology
• Genome Editing
• Interspecies Chimeras
• +6 more

Dr. Jun Wu is an Assistant Professor in the Department of Molecular Biology at UT Southwestern Medical Center. He holds a PhD in Life Science from the University of Tennessee and completed postdoctoral training at the University of Southern California and the Salk Institute. His research focuses on stem cell biology, genome editing, and interspecies chimeras to advance regenerative medicine and developmental biology. Education: Bachelor of Medicine, Shandong University School of Medicine (China) PhD in Life Science, University of Tennessee (2013) Postdoctoral Fellowships: USC (2013-2015) and Salk Institute (2015-2017) Research Interests: Generation of pluripotent stem cells with distinct molecular/phenotypic features Development of interspecies blastocyst complementation systems Modeling peri-implantation human development using stem cell embryo models Study of species-specific developmental barriers and evolutionary biology Application of chimeras to study cancer resistance and organ size determination Lab Activities: The Wu Lab develops stem cell models to study mammalian development and create regenerative therapies. Key projects include: Creation of interspecies chimeras (human-monkey, rat-mouse) Development of blastoids and peri-gastruloids Analysis of species-specific cell competition mechanisms Engineering cross-species organogenesis systems Grant Activities: Focuses on NIH-funded projects related to stem cell biology, interspecies chimerism, and regenerative medicine applications. Collaborates with institutions like Salk Institute and University of California campuses. Lab Team: Includes postdoctoral researchers like Dr. Yi Ding and a multidisciplinary team of molecular biologists, bioengineers, and computational biologists.

• Stem Cell Biology
• Cancer Biology
• Molecular Genetics
• +3 more

Christopher J. Lengner is the Harriet Ellison Woodward Professor and Chair of the Department of Biomedical Sciences at the University of Pennsylvania School of Veterinary Medicine. He is a member of the Institute for Regenerative Medicine, NIH P30 Center for Molecular Studies in Digestive and Liver Diseases, and Abramson Cancer Center, with roles in training and research leadership. Education : PhD in Cell and Molecular Biology from the University of Massachusetts Medical School (2004). His research focuses on molecular mechanisms governing stem cell potency and their dysregulation in diseases like cancer and regenerative failure. Using genetic, genomic, and single-cell approaches in murine and human systems, his lab has uncovered novel pathways in intestinal stem cell hierarchy, cancer ontogeny, and therapeutic targeting. Recent publications highlight work in colorectal cancer metastasis (PI3K/AKT, NOTUM inhibition), intestinal regeneration (mTORC1, FLASH radiotherapy), and tumor microenvironment dynamics. Collaborations span human induced pluripotent cells and patient samples. Scientific Awards : Ruth L. Kirschstein Postdoctoral Fellowship He mentors graduate students (Ryan Cedeno, Maryam Yousefi) and leads the Center for Animal Transgenesis. His lab’s integrative studies bridge basic science to translational applications in oncology and regenerative medicine.

Michael VeitView profile

Associate Professor

• Virology
• Viral Cell Biology
• Virus–Host Membrane Interactions
• +5 more

PD Dr. Michael Veit is an Associate Professor (Privatdozent) at the Institute of Virology, School of Veterinary Medicine, Freie Universität Berlin , where he heads the independent Research Group Veit – Cell Biology of Viral Infections . He is a faculty member of the Center for Infection Medicine and participates in the Berlin Equine Virus Lab (BEVL). Education & Training Doctorate (Dr. rer. nat.) in Virology/Biochemistry – exact institution not stated in text. Post-doctoral qualification (Privatdozent) awarded by Freie Universität Berlin. Research Focus Veit’s laboratory investigates the molecular and cellular biology of enveloped RNA viruses , with emphasis on virus–host membrane interactions and post-translational lipid modifications (S-acylation/palmitoylation). His group combines reverse genetics, live-cell imaging, mass spectrometry and structural approaches to dissect how viral glycoproteins are modified, trafficked and assembled into infectious particles. Model pathogens include influenza A, B, C and D viruses, coronaviruses (SARS-CoV-2, MERS-like CoVs, PHEV, PDCoV), arteriviruses (PRRSV, EAV), alphaviruses (Getah, CHIKV-like), and other emerging zoonotic agents. Publication Trends From 2020 to 2025 Veit has published >30 high-impact articles that cluster around four major themes: (i) coronavirus surveillance and zoonotic risk assessment , (ii) mechanistic dissection of protein acylation in influenza and arteriviruses , (iii) structure-function analysis of viral entry receptors (ACE2, LDLR), and (iv) development of reverse-genetic tools and reporter viruses for antiviral screening. Grants & Collaborative Networks Ongoing third-party funded projects coordinated by Veit are not explicitly listed in the text, but the continuous publication output and mention of “Current Collaborations” imply active grant support. He collaborates closely with other FU Berlin groups (Osterrieder, Kaufer, Azab) and international partners on coronavirus and influenza consortia. Laboratory & Teams The Research Group Veit comprises post-docs, PhD students and technicians working in BSL-2 and BSL-3 facilities at the Institute of Virology. Core platforms include confocal & FLIM microscopy, quantitative proteomics, and reverse-genetics suites for segmented RNA viruses.

Gary K. OwensView profile

Professor

• Cardiovascular Biology
• Atherosclerosis
• Smooth Muscle Cell Biology
• +4 more

Dr. Gary K. Owens is a Professor in the Department of Molecular Physiology and Biological Physics at the University of Virginia , with a secondary appointment in the Department of Medicine, Division of Cardiology. He serves as Director of the Robert M. Berne Cardiovascular Research Center and leads groundbreaking research on vascular smooth muscle cell (SMC) dynamics in atherosclerosis. His work challenges conventional paradigms about SMC roles in plaque stability and thromboembolic events. Primary Affiliation: University of Virginia Key Titles: Robert M. Beirne Professor of Cardiovascular Research, Professor, Director of CVRC Research Themes include: Cardiovascular Biology Atherosclerosis Pathogenesis Smooth Muscle Cell Plasticity Epigenetic Regulation Inflammatory Signaling Tumor Metastasis Mechanisms Publication Trends (2015–2024) reveal expertise in Nature Medicine and Circulation studies, focusing on SMC gene regulation (Klf4/Oct4), plaque stability, and cross-talk between vascular cells and tumors. His work demonstrates that SMCs account for >80% of advanced lesion cells and that Klf4 inhibition reduces metastasis by >70%. Lab Leadership includes mentoring PhD students Anita Salamon and Victoria Milosek , alongside senior scientists and postdocs. Collaborations span with Dr. Gwen Randolph (Washington University) and Dr. Rosey Kaplan (NIH) on IL1β signaling and metastasis.

Ellen RothenbergView profile

Professor

• Cellular and Developmental Biology
• Molecular Biology
• Immunology
• +3 more

Ellen Rothenberg is the Edward B. Lewis Professor of Biology at the California Institute of Technology (Caltech). She earned her A.B. in Biochemical Sciences from Harvard University (1972) and a Ph.D. in Molecular Biology from MIT (1977). Her academic career at Caltech spans roles from Assistant Professor (1982–88) to her current position. She holds the Ruddock Professorship (2007–21), Distinguished Professor (2021–), and Lewis Professor (2021–). Her research focuses on transcriptional networks governing T-cell development and signaling, particularly how hematopoietic stem cells commit to T-lymphocyte lineages. Using in vitro systems, molecular genetics, and genomic approaches, her lab explores transcription factor interactions, chromatin dynamics, and signaling pathways that drive T-cell identity. Key interests include understanding stem-cell multipotentiality loss, irreversible commitment mechanisms, and links to autoimmune predisposition. Rothenberg is an Andrew D. White Professor-at-Large at Cornell University (2021–2027), collaborating with immunology and molecular biology departments. She has organized international conferences, served on NIH review panels, and advises biotech firms like Century Therapeutics. Her honors include membership in the National Academy of Sciences, AAAS and American Academy of Arts and Sciences fellowships, and the Feynman Teaching Prize (2016). Education: A.B., Harvard University, Biochemical Sciences, 1972 Ph.D., Massachusetts Institute of Technology, Molecular Biology, 1977 Awards: AAAS Fellow, American Academy of Arts and Sciences Fellow Member, National Academy of Sciences American Association of Immunologists Distinguished Fellow Richard P. Feynman Prize for Excellence in Teaching (2016) External Roles: Cornell’s ADW-PAL (2021–2027), collaborating with faculty hosts Brian Rudd and Andrew Grimson Scientific Advisor, Century Therapeutics, A2 Biotherapeutics, Kite Pharma Her work bridges basic research and clinical applications, including immunogenomics symposia and public lectures on T-cell programming. Ongoing projects explore evolutionary origins of lymphocyte development through comparative analysis of basal vertebrates.

Isabel ML SaurView profile

Assistant Professor

• Plant Immunity
• Pathogen Recognition Mechanisms
• Signal Transduction Pathways
• +4 more

Dr. Isabel ML Saur is a research group leader at the Institute for Plant Sciences, Faculty of Mathematics and Natural Sciences, University of Cologne. She leads the Saur Lab which focuses on plant-pathogen interactions, particularly the mechanisms employed by the powdery mildew fungus Blumeria hordei to colonize barley. Her research contributes significantly to understanding plant immunity and pathogen recognition mechanisms. Dr. Saur was trained as a Laboratory Assistant in Stuttgart-Hohenheim and completed her undergraduate studies in Biotechnology at the Applied Science University Esslingen am Neckar. She developed her interest in plant sciences during placements at the Research School of Biology, The Australian National University (ANU), Canberra. She earned her PhD in plant immunity from ANU in 2015 and subsequently joined the Max Planck Institute for Plant Breeding Research (MPIPZ) in Cologne. In 2020, she was granted a prestigious DFG Emmy Noether group leader position, establishing her independent research group. Dr. Saur's research focuses on cellular recognition mechanisms in plant immunity, signal transduction pathways linking receptor-mediated recognition to host physiology, and pathogen strategies for immune evasion and effector-mediated immune suppression. Her lab uses the interaction between barley ( Hordeum vulgare ) and the barley powdery mildew fungus Blumeria hordei as a primary model system, complemented by studies in Arabidopsis thaliana and Nicotiana benthamiana to explore both conserved and lineage-specific features of immunity in monocots and dicots. Analysis of Dr. Saur's recent publications reveals a strong focus on plant-pathogen interactions, particularly the molecular mechanisms of effector proteins from powdery mildew fungi and their recognition by plant immune receptors. Her work spans multiple disciplines including plant pathology, molecular biology, structural biology, and plant immunology, with specific attention to NOD-like receptors, cell death mechanisms, and the evolution of resistance gene specificity. Dr. Saur has received significant recognition for her research, most notably: DFG Emmy Noether group leader position (2020) Dr. Saur currently mentors several students and researchers in her lab, including PhD students Merle Bilstein-Schloemer and Sophie Sent, and postdoctoral fellows Ishani Shankar Das and Wei Shi. Her research is supported by multiple projects including her Emmy Noether project on quantification of virulence function, CEPLAS & EN Project on identification of intrinsic functions of effectors, SFB1403 Project on host cell death pathways, and For5682 Project on powdery mildew adaptation to the leaf epidermal cell niche. The Saur Lab maintains a dynamic research environment focused on understanding plant immunity through multiple ongoing projects. The lab actively participates in conferences and collaborations, contributing to the international plant-microbe interaction research community. Recent lab activities include participation in the 2025 IS-MPMI Congress in Cologne and preparation for the 17th International Cereal Rusts and Powdery Mildews Conference in Vancouver.

Filipa SimõesView profile

Research Fellow

• Regenerative Medicine
• Cardiovascular Biology
• Immunology
• +3 more

Filipa Simões is a Group Leader and British Heart Foundation Intermediate Basic Science Research Fellow at the Institute of Developmental and Regenerative Medicine (IDRM), University of Oxford. She holds a Hugh Price Fellowship in Regenerative Medicine at Jesus College, Oxford. Her work focuses on immune cell programming in cardiac repair, leveraging genomics, spatial omics, and in vivo/in vitro models to dissect macrophage roles in heart regeneration. She completed her PhD at the University of Coimbra (Portugal) and postdoctoral research at Oxford, identifying epicardial subpopulations and macrophage contributions to cardiac scarring. Education: BSc Microbiology and Genetics, Faculty of Sciences, University of Lisbon PhD Biochemistry, University of Coimbra (research at Oxford’s Weatherall Institute) Postdoctoral Training: Department of Physiology, Anatomy, and Genetics, University of Oxford Research Interests: Filipa’s lab explores how macrophages are programmed by neighboring cells to repair heart attack damage. Key themes include immune-cell-cardiac crosstalk, fibrosis pathways, and regenerative signaling. Techniques employed span spatial genomics, functional assays, and zebrafish models to map cellular microenvironments. Awards: British Heart Foundation Intermediate Basic Science Research Fellowship British Heart Foundation Centre of Research Excellence Transition Fellowship Teaching: Leads undergraduate courses in Cardiovascular Development, Genomics, and Developmental Biology. Oversees postgraduate modules on cardio-immuno genomics and cardiac regeneration. Labs/Teams: Heads a multidisciplinary team at IDRM, integrating developmental biology, immunology, and regenerative medicine approaches to advance cardiac repair strategies.

Katrien De BockView profile

Professor

• Muscle Microenvironment
• Angiogenesis
• Metabolic Crosstalk
• +4 more

Prof. Dr. Katrien De Bock is a Full Professor and Deputy Head of the Department of Health Sciences and Technology at ETH Zurich. Her research focuses on angiogenesis, metabolic crosstalk in muscle microenvironments, and the impact of exercise on muscle regeneration. She leads a team investigating cellular interactions in skeletal muscle, particularly how metabolic signals regulate blood vessel growth and muscle repair. Key areas include understanding fibroadipogenic progenitors' role in muscle physiology, the role of histamine in exercise responses, and age-related muscle decline. Her work integrates molecular biology, single-cell transcriptomics, and computational approaches to dissect mechanisms underlying tendon pathologies, ischemic muscle injury, and metabolic adaptations to exercise. She supervises Master's programs in Human Movement Science and collaborates on projects involving muscle stem cell therapies and vascular engineering. Prof. De Bock also explores interventions like NAD+ precursors to counteract age-related sarcopenia and promotes translational research in regenerative medicine. Research Interests: Exercise-induced metabolic pathways in muscle repair Angiogenesis regulation in health and disease Hypoxia signaling in tendons and muscles Epigenetic modifications during tissue regeneration Stem cell fate determination in muscle microenvironments Notable Projects: Developing AI-driven histologic analysis for tendinopathy diagnosis Mapping the human brain vasculature at single-cell resolution Testing sulfur amino acid restriction to enhance exercise capacity