Steven Rosen

Steven Rosen is a Professor at the University of California San Francisco (UCSF) with a 40-year research focus on biological sulfation mechanisms in immunology and cancer biology. His work on L-selectin and high endothelial venules (HEVs) established foundational insights into lymphocyte homing, while his discovery of SULF1 and SULF2 sulfatases revealed their roles in tumor progression and biomarker development.

• Education: PhD in Neurobiology from Cornell University, B.A. in Physics from UC Berkeley
• Research Focus: L-selectin ligands, SULF enzyme function, heparan sulfate signaling, immune-tumor interactions

Rosen's 15 most recent publications (2013–2025) span topics including SULF2's oncogenic role in pancreatic and glioblastoma cancers, HEV biomarker utility in tumor-associated lymphoid organs, and novel therapeutic targeting of sulfation pathways. His NIH-funded projects (R01GM057411, R01GM023547, R21CA122025) emphasize glycan-based signaling and immune regulation.

Scientific Awards:

• NIH Merit Award (2005)
• Feulgen Lecture (1993)
• AAAS Fellow (2010)
• Karl Meyer Award (2010)

Rosen has mentored collaborative research on glycobiology and developed function-blocking mAbs against SULF2 for cancer therapy. His work on ELISA-based biomarker detection in blood and body fluids demonstrates translational impact across multiple malignancies.