Ram Raj Singh

Ram Raj Singh is a Professor of Medicine and Pathology and Laboratory Medicine at the University of California Los Angeles (UCLA), where he maintains a dual appointment in the School of Medicine. His research spans multiple areas of immunology and autoimmune diseases, with particular focus on systemic sclerosis and lupus.

Dr. Singh's research interests center on the immunological mechanisms underlying autoimmune diseases, particularly focusing on T-cell and B-cell biology in systemic sclerosis and lupus. His work explores the pathogenesis of autoimmune disorders, examining how innate and adaptive immune responses contribute to tissue damage and disease progression. His research has significant implications for understanding mortality patterns in autoimmune diseases and developing targeted therapies.

Analysis of Dr. Singh's publication record reveals a strong focus on autoimmune disease epidemiology, particularly examining mortality trends in systemic sclerosis and lupus across different demographic groups. His research demonstrates expertise in both clinical and basic immunology, with publications spanning molecular mechanisms of disease to population-level health outcomes. A consistent theme throughout his work is the examination of how immune cell subsets (particularly T cells, B cells, and dendritic cells) contribute to autoimmune pathology.

Dr. Singh has served as Principal Investigator on multiple NIH-funded research projects, including R01, R21, and T32 grants focused on autoimmune diseases. His research portfolio includes investigations into the pathogenesis of lupus dermatitis, gender bias in lupus, and the role of innate B1 B cells in lung hemorrhage. He has contributed significantly to understanding the immunological basis of autoimmune diseases and their clinical manifestations.