
About
Min Lu is an Associate Professor in the Department of Biochemistry and Molecular Biology at Rosalind Franklin University's Chicago Medical School, where she leads structural biology research on membrane transport proteins. She is affiliated with the Center for Proteomics and Molecular Therapeutics and maintains active collaborations across the university's research ecosystem.
Her academic background includes:
- PhD in Molecular Biophysics and Biochemistry from Yale University (2001)
- Research Fellowship at Memorial Sloan-Kettering Cancer Center (2002-2004)
- Research Associate position at Brookhaven National Laboratory (2005-2008)
Dr. Lu's research program centers on X-ray crystallography of membrane transport proteins, with dual focus on bacterial nutrient transporters and human MATE transporters implicated in drug resistance. Her NIH-funded work on MATE transporters aims to elucidate structural mechanisms of multidrug efflux to develop resistance-countering strategies. The lab's publication record demonstrates expertise in solving challenging membrane protein structures, including those with crystallographic complications like anisotropy and twinning.
Current funding supports active recruitment of graduate students and postdoctoral fellows, with emphasis on candidates possessing membrane protein purification skills. The lab leverages proximity to Argonne National Laboratory's Advanced Photon Source for cutting-edge structural studies.
Dr. Lu's research bridges fundamental structural biology and therapeutic applications, particularly in overcoming antimicrobial and chemotherapy resistance through mechanistic understanding of transporter proteins.
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