Michelle Choe

Dr. Michelle Choe is an Assistant Professor in the Department of Pediatrics at the University of Washington School of Medicine and a member of the Clinical Research Division at Fred Hutchinson Cancer Center (Fred Hutch). She serves as an Attending Physician at Seattle Children's Hospital, specializing in hematopoietic stem cell transplantation and pediatric solid tumors, with a deeply personal commitment stemming from her own diagnosis of parosteal osteosarcoma as a young adult.

Her educational background includes:

• MD from Loma Linda School of Medicine (2016)
• BA from Johns Hopkins University (2010)
• Residency in Pediatrics at University of California, Irvine/Children’s Hospital Orange County (2019)
• Pediatric Hematology Oncology Fellowship at Baylor College of Medicine/Texas Children’s Hospital (2022)
• Pediatric Bone Marrow Transplantation & Immunotherapy Fellowship at Fred Hutch/Seattle Children’s Hospital (2024)

Dr. Choe's research focuses on developing cellular therapies for aggressive pediatric solid tumors, particularly sarcomas. Her work centers on clinical trials for adoptive immunotherapy using CAR T-cell engineering, targeting recurrent/refractory osteosarcoma (FOLR1-CAR T cells) and Ewing sarcoma (STEAP1-CAR T cells). This translational research bridges her clinical expertise in hematopoietic stem cell transplantation with innovative gene therapy approaches to address critical unmet needs in pediatric oncology.

As a member of Fred Hutch's Immunotherapy Integrated Research Center (IIRC), she collaborates on advancing immunotherapeutic strategies while maintaining active clinical responsibilities at Seattle Children's Hospital. Scientific awards: None mentioned in the provided text.

Dr. Choe's current work emphasizes translating laboratory discoveries into clinical applications through ongoing trials, with future directions likely expanding CAR T-cell targets and optimizing cellular therapies for pediatric sarcomas. She maintains strong institutional ties across Fred Hutch, University of Washington, and Seattle Children's Hospital in her dual research-clinical role.