Kyle R Sweeney

Kyle R Sweeney, MD serves as an Associate Professor in the Department of Orthopedic Surgery and Sports Medicine at the University of Kansas Medical Center. He is a specialist in musculoskeletal oncology and reconstructive surgery with expertise in diagnosing and treating bone and soft tissue cancers across all age groups from infants to octogenarians.

His educational background includes:

• BS in Human Biology and Human Physiology from Michigan State University
• MD from Vanderbilt University School of Medicine
• Orthopedic Surgery Residency at Emory University
• Musculoskeletal Oncology Fellowship at the University of Chicago

Dr. Sweeney's clinical practice focuses on sarcoma, bone cancer, benign bone tumors, benign soft tissue tumors, and metastatic cancers affecting bone including breast, prostate, kidney, lung, and thyroid cancers. His surgical expertise encompasses radical resections of sarcoma, limb salvage procedures, joint reconstruction, rotationplasty, and hip replacements for patients with arthritis. His professional mission centers on empowering patients through education and coordinated care with multidisciplinary teams including medical oncologists, radiologists, pathologists, and radiation oncologists.

His research portfolio demonstrates a consistent focus on improving outcomes for orthopedic oncology patients, particularly examining the role of tranexamic acid in reducing blood loss and transfusion requirements during cancer-related orthopedic procedures. His publications reveal growing interest in cost-effectiveness analysis and comparative effectiveness of different treatment modalities for bone tumors.

Dr. Sweeney maintains active professional engagement through multiple society memberships including:

• Council of Orthopaedic Residency Directors (2023-Present)
• Kansas Orthopaedic Society (Vice President, 2023-Present)
• Musculoskeletal Tumor Society (Education Committee, 2023-Present)
• Musculoskeletal Oncology Research Initiative (Board of Directors, 2019-Present)

His current research includes a prospective randomized controlled trial examining the local bisphosphonate effect on recurrence rate in extremity giant cell tumor of bone, conducted with St. Louis University as Co-Investigator.