About
Johan Rosengren is an Associate Professor at the School of Biomedical Sciences, University of Queensland, where he heads the peptide structural biology lab. His research focuses on the structure-activity relationships of bioactive peptides, particularly peptide hormones, and the application of NMR spectroscopy in designing novel peptide drug leads.
Education:
- PhD (2003) from the Institute for Molecular Bioscience, University of Queensland, under Professor David Craik, focusing on structure-activity relationships of antimicrobial peptides
Research Interests:
Dr. Rosengren's research spans multiple areas of peptide science, with particular emphasis on:
- Structural biology of bioactive peptides using NMR spectroscopy
- Structure-activity relationships of peptide hormones and toxins
- Design and engineering of novel peptide therapeutics
- Conotoxins and other venom peptides
- Cyclic peptides and their applications
Recent Publication Trends:
Dr. Rosengren's recent work (2021-2025) demonstrates a strong focus on peptide engineering for therapeutic applications. His research spans multiple areas including venom peptide characterization (conotoxins, spider toxins, scorpion toxins), peptide modification techniques (hydroxylation, amidation, stapling), and applications in pain management, immunomodulation, and DNA repair. A notable trend is the application of structural insights to engineer peptides with improved stability, selectivity, and potency for various biological targets.
Scientific Awards and Recognition:
- NHMRC Career Development Award
- ARC Future Fellowship
Supervision and Research Support:
Dr. Rosengren actively supervises PhD and MPhil students at the University of Queensland. His research is supported by competitive funding including NHMRC and ARC grants. He has established productive collaborations with numerous research groups both within Australia and internationally, particularly in the fields of peptide science and structural biology.
Laboratory and Research Teams:
Dr. Rosengren heads the peptide structural biology lab at the University of Queensland's School of Biomedical Sciences. His team employs a multidisciplinary approach combining NMR spectroscopy, chemical synthesis, molecular biology, and functional assays to investigate peptide structure and function. The lab maintains strong collaborations with other research groups focusing on peptide therapeutics, venom biology, and structural biology.
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