Brett Graham

Professor Brett Graham is a leading researcher at the University of Newcastle's School of Biomedical Sciences and Pharmacy, specializing in spinal cord sensory coding and pain signaling mechanisms. His work focuses on mapping neural circuits involved in pain transmission and modulation.

• PhD in Biomedical Science (University of Newcastle)
• Bachelor of Biomedical Sciences (University of Newcastle)

Research interests include:

• Spinal Cord Pain Circuits - Investigating how nerve cells process and transmit pain signals
• Neuroinflammation - Studying age-related changes in spinal cord gene expression
• Optogenetics - Using light-activated proteins to map neural pathways
• Synaptic Plasticity - Exploring changes in neural connections during chronic pain

His 15 most recent articles (2015-2025) reveal a consistent focus on:

• Spinal cord microcircuitry (40% of articles)
• Neuropathic pain mechanisms (35% of articles)
• Optogenetic and transgenic techniques (25% of articles)
• Synaptic transmission dynamics (20% of articles)
• Pain modulation strategies (15% of articles)

Scientific contributions include:

• Co-developing transgenic mouse models for pain research
• Pioneering work on glycinergic inhibition in spinal cord neurons
• Advancing understanding of visceral pain processing

As a research supervisor, he has mentored students working on:

• Spinal cord circuit mapping
• Chronic pain treatment development
• Pain signal modulation techniques
• Age-related changes in pain processing