About
Mark L. Baccei is a Professor of Anesthesiology at the University of Cincinnati College of Medicine. His research focuses on the neurobiological basis of pediatric chronic pain, particularly how neonatal tissue damage alters spinal nociceptive circuits. He employs techniques such as in vitro electrophysiology, optogenetics, and behavioral assays to study synaptic organization in the superficial dorsal horn of the spinal cord.
- Bachelor's: Psychology, Duke University (1994)
- Master's: Neuroscience, Yale University (1997)
- PhD: Neuroscience, Yale University (2001)
His laboratory investigates long-term consequences of early-life injury on pain processing, with an emphasis on molecular and cellular mechanisms. Key areas include GABAergic inhibition, synaptic plasticity, and spinal circuit reorganization. Grants from the National Institutes of Health and other federal agencies support his work.
The 15 most recent articles highlight his contributions to understanding spinal cord pain pathways, stress hormone effects on neurons, and genetic models for studying nociception. These studies span neurophysiology, molecular biology, and translational pain research.
Dr. Baccei collaborates with researchers across neuroscience, anesthesiology, and psychiatry, including projects on corticospinal circuits and cancer metabolism. His leadership in federal grants and mentorship in predoctoral training programs underscores his impact in the field.
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