İhsan Cihan Ayanoğlu

İhsan Cihan Ayanoğlu is an Instructor in the Department of Biological Sciences at Middle East Technical University (METU), Ankara, Turkey. He holds a B.Sc., M.Sc., and Ph.D. in Biological Sciences from METU, completed between 2005–2019. His research focuses on innate immunity, with emphasis on immune responses to pathogens, vaccine development, and host-microbe interactions. Key areas include Leishmania infections, SARS-CoV-2 vaccine efficacy, and the role of extracellular vesicles in immunomodulation.

Education:

• B.Sc. Biological Sciences, METU (2005–2010)
• M.Sc. Biological Sciences, METU (2010–2013)
• Ph.D. Biological Sciences, METU (2013–2019)

Research interests span innate immune mechanisms, including parasite-host interactions, cytokine signaling pathways, and the development of therapeutic strategies using biotherapeutic agents. His work integrates molecular biology, immunology, and virology to address challenges in infectious diseases and cancer therapy.

Publications highlight studies on Leishmania kinetoplast DNA’s role in macrophage parasitemia, SARS-CoV-2 vaccine design via virus-like particles, and the immunomodulatory effects of human gut microbiota-derived vesicles. Collaborative projects include investigations into altitude’s impact on immune defense in subterranean rodents and NETosis defects in genetic immunodeficiencies.

No scientific awards are explicitly listed, though his contributions to vaccine research and innate immunity are notable. His role as an instructor involves teaching and mentoring within the department. Research is conducted in collaboration with teams at METU and international institutions, though specific lab affiliations are not detailed in the provided text.