جستجوی استاد راهنمای دانشگاهی

Joel Blanchardمشاهده پروفایل

دانشیار

• Neuroscience
• Stem Cell Biology
• Neurodegeneration
• +۱۲ مورد دیگر

Joel Blanchard, PhD, is an Associate Professor in the Departments of Neuroscience and Cell, Developmental & Regenerative Biology at the Icahn School of Medicine at Mount Sinai. He is also an Investigator at the Black Family Stem Cell Institute and the Ronald Loeb Center for Alzheimer’s Disease. His research focuses on developing human brain models using induced pluripotent stem cells to study and treat neurodegenerative diseases. Education: BS, St. Lawrence University MLA, Harvard University PhD, The Scripps Research Institute & MIT Research Interests: Dr. Blanchard’s lab is dedicated to understanding the genetic and environmental vulnerabilities that lead to neurodegeneration. His team develops cutting-edge 3D brain organoids and blood-brain barrier models to investigate diseases like Alzheimer’s, Parkinson’s, and ALS. A major focus is on the role of APOE4 in myelination, cholesterol metabolism, and vascular dysfunction. Scientific Awards: Friedman Brain Institute Scholar Award (2021) ISSCR Merit Award (2019) Glenn Foundation Postdoctoral Fellowship (2018) California Institute for Regenerative Medicine Pre-doctoral Fellowship (2011) Funding & Grants: Dr. Blanchard’s lab is currently funded by NASA, NIH, and the Cure Alzheimer’s Fund. Active projects include the development of miBrain (multicellular integrated brain tissue), blood-brain barrier modeling, and APOE4-mediated mechanisms of neurodegeneration. Lab & Team: The Blanchard Lab is a multidisciplinary team of postdocs, graduate students, and research associates. The lab is actively recruiting postdoctoral fellows and is known for its collaborative, innovative environment focused on translational neuroscience.

Sarah Jonesمشاهده پروفایل

دانشیار

• Thrombosis
• Haemostasis
• Platelet Biology
• +۳ مورد دیگر

Dr. Sarah Jones is an Associate Professor in Thrombosis and Haemostasis at Manchester Metropolitan University, serving as Deputy Director of Research for the Department of Life Sciences. She leads the Thrombosis Group and holds an honorary Reader position at the University of Manchester. Academic Affiliation: Manchester Metropolitan University Secondary Appointment: University of Manchester (Honorary Reader) Over 20 years, Dr. Jones has pioneered research on platelet signaling pathways and their role in thrombosis. Her current work focuses on platelet-endothelial crosstalk in disease states, with emphasis on in vitro thrombosis modeling to replace animal testing. This research, funded by BBSRC, NC3Rs, and BHF, addresses cardiovascular disease mechanisms and translational antithrombotic testing. Her scientific publications demonstrate expertise in platelet biology (Pim kinase signaling, SIRT1 regulation, proteoglycan interactions) and thrombosis modeling. Recent work includes placental perfusion studies for pregnancy-related cardiovascular complications. Grants & Projects: UKRI (NC3Rs) Partnership and Impact Award (2025-2026) UKRI BBSRC/NC3Rs grant for human haemostasis models (2023-2025) British Heart Foundation collaborations (2021-2025) Dr. Jones supervises PhD students (Mishaal Reyman, Poppy White, etc.) and teaches on Biomedical Science, Cellular Science, and Clinical Haematology programs. She has developed innovative endothelialised in-vitro thrombosis models that reduce animal usage in cardiovascular research.

• Cerebral Microcirculation
• Vascular Biology
• Endothelial Cell Function
• +۶ مورد دیگر

William Mayhan is a Professor in Biomedical Sciences at the University of South Dakota . His research focuses on cerebral microcirculation and vascular biology , particularly examining endothelial cell function in disease states like diabetes and alcohol consumption. Education: PhD in Biomedical Sciences, University of Nebraska Medical Center (1983) Post-Doctoral Fellowship, University of Iowa (1985) BS in Biology, Creighton University (1977) His work investigates blood-brain barrier permeability and cerebral vasculature responses to hypertension, diabetes, and alcohol. Key findings include mechanisms of nitric oxide synthase (NOS) dysfunction and oxidative stress in diabetic and alcoholic models. Recent publications analyze prenatal alcohol exposure effects on cerebral arterioles and CB2 receptor agonists for vascular protection in diabetes. His studies span in vivo models, potassium channel dynamics , and inflammatory mediators in stroke pathogenesis.

Stuart Allanمشاهده پروفایل

استاد

• Neuroinflammation
• Stroke Pathology
• Cytokine Signaling
• +۳ مورد دیگر

Stuart Allan is Professor of Neuroscience at the University of Manchester's Faculty of Life Sciences, Division of Neuroscience. His research focuses on neuroinflammation mechanisms in stroke and neurodegenerative diseases, with particular expertise in cytokine signaling (especially IL-1) and neuronal injury pathways. He leads projects targeting interleukin-1 for acute brain injury treatment and investigates stroke-immune mediated pathways in cognitive trajectory. Research Interests: Neuroinflammatory responses, cytokine-mediated neuronal injury, stroke pathophysiology, Alzheimer's disease mechanisms, and neurovascular coupling. His work bridges experimental paradigms (in vitro and in vivo) with clinical applications. Education: PhD Biomedical Sciences (University of Aberdeen, 1990-1993) BSc Pharmacology (University of Dundee, 1986-1990) Professional Appointments: Professor of Neuroscience (2012-present) Senior Lecturer (2008-2012) Lecturer (2002-2008) Postdoctoral Research Associate (1993-2002) Research Beacons & Institutes: Dementia@Manchester, Manchester Regenerative Medicine Network, Lydia Becker Institute, Christabel Pankhurst Institute, Manchester Institute for Collaborative Research on Ageing. Scientific Output: 179 research outputs including articles on cerebrovascular health, neurovascular coupling, and cytokine mechanisms in stroke models. Research demonstrates consistent focus on translational neuroscience and neuroinflammatory pathways.

• Stem Cell Biology
• Cardiovascular Medicine
• Tissue Engineering
• +۵ مورد دیگر

Yibing Qyang is a Professor of Medicine (Cardiovascular Medicine) at Yale University School of Medicine (YSM), affiliated with the Department of Internal Medicine. He serves as Director of the Yale Stem Cell Research Forum since 2010. His expertise spans stem cell biology, cardiovascular disease modeling, and regenerative medicine. Qyang holds a B.S. from Nanjing University, an M.S. from Chinese Academy of Sciences, and a Ph.D. from the University of Texas M.D. Anderson Cancer Center. He completed postdoctoral training at UC San Diego and Harvard Medical School. Research Interests: The Qyang Lab focuses on engineering vascular tissues using induced pluripotent stem cells (iPSCs), elucidating cardiovascular disease mechanisms, and developing therapeutic strategies. Key areas include: Vascular tissue engineering for graft development Stem cell-derived models of diseases like supravalvular aortic stenosis Cardiac progenitor cell therapies for heart repair Biomechanical signaling in hypertrophic cardiomyopathy Preclinical porcine models for translational research Key Achievements: Developed immunocompatible 'universal donor' vascular grafts using CRISPR-engineered iPSCs Pioneered iPSC-derived vascular smooth muscle and endothelial cells for tissue engineering Identified elastin-based therapies for supravalvular aortic stenosis Grants & Awards: Connecticut Stem Cell Program Established Investigator Awards (2011, 2015) ISSCR Membership (2007–Present) Highlighted in Yale News for groundbreaking discoveries in heart disease and vascular grafts Lab Team & Collaborations: The lab includes researchers and students from institutions worldwide, with collaborations at Harvard, UCSD, and Yale’s Cardiovascular Research Center. Projects span iPSC differentiation, biomechanical modeling, and preclinical trials. Future Directions: Expanding studies on universal donor grafts, cardiac tissue engineering, and clinical translation of iPSC-derived therapies.

Stelios Andreadisمشاهده پروفایل

استاد

• Stem Cell Engineering
• Tissue Engineering
• Cell Adhesion Signaling
• +۳ مورد دیگر

Stelios Andreadis is the SUNY Distinguished Professor of Chemical and Biological Engineering at the University at Buffalo, affiliated with the School of Engineering and Applied Sciences. He directs the Cell, Gene and Tissue Engineering Center and previously led the Stem Cells in Regenerative Medicine (SCiRM) Training Program. His research focuses on stem cell bioengineering, vascular and gland tissue engineering, and biomaterials design. He holds a PhD in Chemical Engineering from the University of Michigan and has been funded by NIH, NSF, and NYSTEM, totaling over $20M. His awards include the NSF CAREER Award, SUNY Chancellor’s Excellence in Scholarship, and AIMBE and BMES Fellowships. Research interests span stem cell rejuvenation, cell-free vascular grafts, and metabolic reprogramming. He has published 140+ papers and advised 28 PhD students, many now in academia or industry. His lab co-founded Angiograft, LLC to commercialize vascular grafts. Key achievements include developing self-healing vascular grafts and demonstrating monocyte recruitment for vascular regeneration. His work bridges basic science and clinical applications in regenerative medicine.

Philip R Hollandمشاهده پروفایل

دانشیار

• Neuroscience
• Migraine Research
• Headache Disorders
• +۳ مورد دیگر

Dr. Philip R. Holland is a Reader in Neuroscience at King's College London, affiliated with the Wolfson Sensory, Pain and Regeneration Centre within the School of Neuroscience and the Institute of Psychiatry, Psychology & Neuroscience. His research focuses on understanding migraine mechanisms and developing therapies, with a particular emphasis on neurovascular interactions and pain pathways. He leads a team funded by organizations like the Medical Research Council, Wellcome Trust, and European Research Council. Dr. Holland earned his PhD under Prof. Peter Goadsby at University College London, followed by postdoctoral research at UCSF and the University of Edinburgh. He actively engages in teaching, public awareness, and editorial roles (e.g., Cephalalgia). Key awards include the 2020 Medical Research Foundation Emerging Leaders Prize. His work spans clinical and translational research, aiming to bridge basic science with patient care. Education: PhD in Neuroscience, Postgraduate Certificate in Academic Practice (King's College London). External Roles: External Examiner at UCL, Science Editor of CGRP Forum, Associate Editor of Cephalalgia. Grants/Projects: Investigates trigeminal autonomic cephalalgias, neuroendocrine signaling, and novel therapies like cannabidiol combinations. Labs/Teams: Leads a migraine-focused research group exploring neurobiological and pharmacological interventions.

• Cadmium Toxicology
• Environmental Pollutants
• Pharmacology
• +۵ مورد دیگر

Professor Walter C. Prozialeck is a distinguished academic at Midwestern University, serving in the Department of Pharmacology across multiple schools including the Chicago College of Osteopathic Medicine (CCOM), College of Pharmacy, College of Dental Medicine-Illinois, and College of Graduate Studies - Illinois. He holds a Ph.D. in Pharmacology from Thomas Jefferson University (1978) and a B.S. from Juniata College (1974). Dr. Prozialeck's research spans 35 years of cadmium toxicology, focusing on mechanisms of nephrotoxicity, microRNA expression, and biomarker development. He also investigates vancomycin pharmacokinetics and herbal medications like kratom and marijuana, contributing to drug policy discussions. His work has secured over $3.0 million in NIH funding. Recent publications highlight his expertise in cadmium-induced kidney injury biomarkers (e.g., Kim-1, cystatin C), microRNA alterations, and vascular toxicity. He has authored over 100 papers and book chapters. Career Achievement Award, Metals Specialty Section of Society of Toxicology (2021) Dr. Prozialeck teaches Pharmacology to medical, pharmacy, optometry, dental, and allied health students, and lectures in CME programs. He has held leadership roles including President of the Great Lakes Chapter of ASPET and Midwest Regional Chapter of the Society of Toxicology.

• Clinical sciences
• Neurosciences
• Medical physiology
• +۲ مورد دیگر

Jinhong Meng is a Senior Research Fellow at the Department of Genetics & Genomic Medicine, University College London (UCL), focusing on neuromuscular disorders and gene therapy. He earned his PhD and Bachelor’s degrees from the Fourth Military Medical University. Education: Doctor of Philosophy, Fourth Military Medical University (2000) Bachelor, Fourth Military Medical University (1995) Research Interests: Jinhong Meng’s work centers on Duchenne Muscular Dystrophy (DMD), Spinal Muscular Atrophy (SMA), and gene therapy techniques including CRISPR, lentiviral vectors, and antisense oligonucleotides. His studies explore immune responses to dystrophin, vascular defects in SMA, and dystrophin correction via viral and non-viral delivery systems. Publication Trends: Over the past eight years, Jinhong Meng has published extensively on DMD and SMA, with a focus on gene editing, dystrophin restoration, and cellular therapies. His collaborative work spans lentiviral vectors, foamy virus transduction, and necroptosis mechanisms in muscle degeneration. Labs & Collaborations: He works within UCL’s Genetics & Genomic Medicine Department, collaborating on projects involving dystrophic muscle engraftment, circadian signaling, and RNA editing for genetic mutations.

• Heart Failure
• Cardiovascular Immunology
• Cardiac Inflammation
• +۳ مورد دیگر

Xiaochen He serves as an Instructor in the Department of Physiology & Biophysics at the University of Mississippi Medical Center's School of Medicine, where he focuses on cardiovascular research and teaching within this foundational medical science department. His research program centers on the intersection of cardiac pathophysiology and immunometabolism, with core interests including: Mechanisms of immune-mediated cardiac inflammation in heart failure Role of T cell subsets (Th17, γδ T, CD8+) in pressure overload models Molecular regulation by IL-12 family cytokines and metabolic enzymes (TIGAR, SIRT3) Endothelial dysfunction in cardiac hypertrophy and failure progression Therapeutic interventions targeting inflammatory pathways Analysis of Dr. He's recent publications (2022-2025) reveals a concentrated research trajectory investigating how specific immune pathways drive heart failure progression. His work consistently employs genetic mouse models to demonstrate that IL-12β inhibition, TIGAR deficiency, and selenium supplementation attenuate cardiac inflammation and dysfunction, while CD8+ T cell metabolic reprogramming exacerbates disease. Key discoveries include GPR174's role in Th17 differentiation and NK1.1 signaling's contribution to cardiopulmonary inflammation, establishing critical immune-metabolic axes in heart failure pathogenesis. No scientific awards were documented in the available profile information. Current departmental records indicate no graduate students are formally listed under Dr. He's mentorship, and no research grants are specified in the public profile. Details regarding laboratory infrastructure, research teams, or collaborative networks were not provided in the available institutional documentation.

Naftali Razمشاهده پروفایل

استاد

• Human Brain Aging
• Cognitive Aging
• Metabolic Risk Factors
• +۴ مورد دیگر

Naftali Raz is a Professor of Psychology at Stony Brook University, specializing in Integrative Neuroscience. He holds a Ph.D. from the University of Texas at Austin (1985) and a B.A. from the Hebrew University of Jerusalem (1979). His research focuses on understanding age-related changes in the brain and cognition, particularly exploring metabolic, vascular, and inflammatory risk factors influencing cognitive aging. He employs neuroimaging techniques such as MRI, MRS, and fMRI to study brain structure, function, and metabolism in healthy aging populations. Raz’s research emphasizes the 'FRIENDS' model (Free-Radical Induced Energetic and Neural Decline in Senescence), linking aging to energy production decline. His work includes longitudinal studies on brain atrophy, myelin content, and iron accumulation. He investigates how physiological risk factors like cardiovascular disease and metabolic syndrome impact neurocognitive trajectories. Current grants include NIA funding for neural correlates of cognitive aging and hippocampal glutamate modulation studies. Education: Ph.D. in Psychology, University of Texas at Austin (1985) B.A. in Psychology, Hebrew University, Jerusalem, Israel (1979) Labs/Facilities: Integrative Neuroscience Group, SCAN Center (Stony Brook Advanced Neuroimaging) His publications span over three decades, with recent works on recognition memory strategies, hippocampal subfield analysis, and cerebral blood flow dynamics. Collaborations include multi-institutional projects on neuroimaging protocols and aging mechanisms.

• Sepsis
• Innate Immunity
• Neonatal Immunology
• +۵ مورد دیگر

Andrew Currie is a Professor and Associate Dean (Research & Innovation) at Murdoch University's School of Medical, Molecular and Forensic Sciences, within the College of Environmental and Life Sciences. He leads the Sepsis Diagnostics Research Group at the Centre for Molecular Medicine and Innovative Therapeutics and co-heads the Neonatal Infection and Immunity Team with Clinical Professor Tobias Strunk at the Wesfarmers Centre of Vaccine & Infectious Diseases at Telethon Kids Institute. His research focuses on immunology and infectious diseases in pediatric populations, particularly sepsis diagnostics and neonatal immunity. Education: PhD (Immunology, University of Western Australia, 2001); BSc (Biotechnology with Honors, Murdoch University, 1997). Research Interests: Sepsis diagnostics, innate immunity mechanisms in neonates, medical biotechnology for diagnostics (e.g., biosensors), and translational research in pediatric infections. Collaborates internationally with institutions in Canada, Denmark, the UK, US, and China. Aims to reduce sepsis burden in vulnerable populations through advanced molecular methods and interdisciplinary partnerships. Key Affiliations: Lead of Sepsis Diagnostics Research Group (Murdoch University), Senior Lecturer in Immunology, Honorary Associate at Kids Research Institute Australia. Past roles include leadership in the Centre for Molecular Medicine and Innovative Therapeutics. Scientific Contributions: Over 100 peer-reviewed articles focusing on sepsis biomarkers, neonatal immunity, tick-borne diseases, and clinical trials for interventions like vitamin C and probiotics in critical illness. Active in developing precision medicine approaches for neonatal sepsis. Grants & Funding: Co-leads major projects on sepsis diagnostics and neonatal infection, supported by national and international grants. Collaborates on multi-institutional initiatives. Labs/Teams: Sepsis Diagnostics Research Group (Murdoch) and Neonatal Infection and Immunity Team (Telethon Kids Institute). Works closely with the Personalised Medicine Centre and Health Futures Institute.

Tohru Fukaiمشاهده پروفایل

استاد

• Oxidative stress
• Cardiovascular disease
• Metabolic disease
• +۷ مورد دیگر

Tohru Fukai is a Professor and holds the Barbara A. Schnuck Endowed Chair in Translational Medicine at the Medical College of Georgia, Augusta University, where he serves in the Department of Pharmacology and Toxicology. His research is centered at the Vascular Biology Center, where he leads a productive laboratory investigating the molecular mechanisms of oxidative stress and dysfunctional copper metabolism in cardiovascular and metabolic diseases. Dr. Fukai earned his MD in 1988 and PhD in Medical Science in 1995, both from Kyushu University in Japan. Following his medical and doctoral training, he completed postdoctoral fellowship at Emory University School of Medicine in Atlanta from 1995-1999. His research focuses on oxidative stress in cardiovascular and metabolic disease pathogenesis, particularly investigating the role of extracellular SOD (ecSOD, SOD3) and copper transport proteins. His lab has pioneered research on copper transport proteins CTR1, Atox1, and ATP7A in regulating vascular function, demonstrating their critical roles in hypertension, vascular remodeling, inflammatory angiogenesis, atherosclerosis, and diabetes. Notably, his team discovered that copper chaperone Atox1 functions as a copper-dependent transcription factor regulating cell proliferation and inflammatory responses. Analysis of Dr. Fukai's recent publications reveals a strong focus on the intersection of redox signaling, copper metabolism, and vascular function. His work increasingly explores how oxidative stress and copper transport mechanisms contribute to conditions like diabetes, atherosclerosis, Alzheimer's disease, and ischemic injury. A prominent theme across his recent work is the role of protein modifications (particularly sulfenylation and SUMOylation) in regulating vascular responses to oxidative stress, with significant implications for therapeutic interventions. Dr. Fukai's scientific achievements have been recognized with numerous awards including the Barbara A. Schnuck Endowed Chair in Translational Medicine (2017), World Science Leaders in Human Biology Program (2021), and multiple Circulation Research Reviewer Awards. He has served on editorial boards for prestigious journals including Scientific Reports, Journal of Molecular and Cellular Cardiology, and American Journal of Physiology-Heart and Circulatory Physiology. As a mentor, Dr. Fukai has advised numerous graduate students and postdoctoral fellows, including several who have received AHA awards and trainee recognition. He serves on various committees including the VBC post-doc evaluation committee and the CNVAMC Subcommittee for Research Safety. His lab has secured significant funding, including a recent $11.3 million NIH grant for vascular disease research. Dr. Fukai leads an active research group at the Vascular Biology Center comprising senior research associates, assistant research scientists, postdoctoral fellows, and graduate students working collaboratively on multiple projects related to copper transport, redox signaling, and vascular disease mechanisms. His lab has made seminal contributions to understanding how copper transport proteins function as key regulators of vascular antioxidant enzymes and as unexpected signaling molecules in inflammatory disease processes.

• Artificial Intelligence
• Machine Learning
• Signal Processing
• +۴ مورد دیگر

Zachi Attia, Ph.D., M.B.A., is an Associate Professor at the Mayo Clinic College of Medicine and Science, Rochester, Minnesota. His research focuses on applying artificial intelligence (AI) and machine learning to cardiac biosignals, particularly for early disease detection and prediction. He holds primary and joint appointments as Consultant in AI within the Department of Cardiovascular Medicine, collaborating with the Center for Digital Health and the Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery. Education: Ph.D. in Electrical Engineering from the University of Minnesota, Rochester; BSc and MSc in Electrical Engineering from Ben Gurion University, Israel. Dr. Attia's work centers on developing AI models that analyze multimodal cardiac data (ECGs, echocardiograms, angiograms) to detect silent diseases. His research includes pragmatic clinical trials to validate AI's impact on patient outcomes, explainable AI for biological insights, and integrating AI dashboards into medical records for clinical usability. Recent publications highlight AI applications in detecting atrial fibrillation, hypertrophic cardiomyopathy, and pulmonary hypertension via ECG analysis. Scientific Awards: No explicit awards mentioned in the text. Email: attia.itzhak@mayo.edu

• Echocardiography
• Cardiac Imaging
• Right Heart Function
• +۵ مورد دیگر

Karima Addetia serves as an Associate Professor in the Department of Medicine-Cardiology at the University of Chicago. Her academic career has been dedicated to advancing echocardiographic techniques and their clinical applications, particularly in the assessment of right heart function, cardiac amyloidosis, and tricuspid valve pathology. She has established herself as a leading researcher in cardiac imaging through extensive collaborations with the World Alliance of Societies of Echocardiography (WASE) and frequent co-authorship with Dr. Roberto M. Lang, a prominent figure in cardiovascular imaging. Dr. Addetia's research interests span multiple critical areas in cardiovascular medicine. She has pioneered work in right heart assessment, establishing normative values for right ventricular size and function through large-scale multicenter studies. Her investigations into cardiac amyloidosis have significantly advanced the understanding of echocardiographic patterns associated with this condition, particularly regarding apical sparing and strain patterns. She has also made substantial contributions to tricuspid valve assessment, examining both normal anatomy and pathological conditions including device-related complications. More recently, her work has incorporated artificial intelligence applications in echocardiography, exploring how machine learning can improve diagnostic accuracy and workflow efficiency. The trajectory of Dr. Addetia's research publications reveals a consistent focus on quantitative cardiac imaging with increasing sophistication over time. Her early work established foundational knowledge about right ventricular morphology and function, while more recent publications integrate advanced technologies like AI and focus on specific disease states like cardiac amyloidosis. A notable pattern is her participation in large, collaborative studies that establish normative values across diverse populations, addressing important gaps in understanding how cardiac measurements vary by age, sex, and ethnicity. Her work consistently bridges technical echocardiographic advancements with direct clinical applications. Dr. Addetia's collaborative approach is evident through her extensive involvement with the WASE study group and numerous multicenter investigations. Her research methodology typically combines rigorous quantitative analysis with clinical correlation, producing findings that directly impact diagnostic criteria and clinical practice guidelines. While specific grant information isn't detailed in the available publications, her leadership in major collaborative studies suggests significant research funding support for her work in cardiac imaging innovation.