Theresa Scharl-Hirsch is a Senior Scientist and Deputy Scientific Director at the Core Facility Bioinformatics, University of Natural Resources and Life Sciences, Vienna (BOKU). She holds concurrent appointments at the Institute of Statistics, BOKU, and has extensive experience in bioprocess modeling, machine learning, and statistical computing. Her work bridges biochemical engineering with advanced data science methodologies. Her research focuses on real-time monitoring of biopharmaceutical processes, clustering of high-dimensional data (particularly RNA sequencing), and application of explainable machine learning techniques. She has developed statistical models for process optimization and quality prediction in antibody capture and protein purification, with a strong emphasis on industrial implementations using R programming. Key trends in her publications include three-way data analysis, matrix-variate Gaussian mixture models, and permutation-based variable importance methods for deep learning architectures. Her work spans bioprocess engineering, bioinformatics, and industrial data science applications.
