جستجوی استاد راهنمای دانشگاهی

Lars Andreas Akslen is a Professor at the Department of Clinical Medicine, University of Bergen, and serves as the Centre Director of CCBIO (Centre for Cancer Biomarkers). He is based at Haukeland University Hospital and leads a major translational cancer research group focused on biomarker discovery and validation. Position: Professor, Centre Director of CCBIO Institution: University of Bergen Department: Department of Clinical Medicine Location: Haukeland University Hospital, Bergen, Norway Email: lars.akslen@uib.no His research is centered on translational oncology, with a strong emphasis on identifying and validating novel biomarkers for improved biological classification and grading of malignant tumors. His work spans breast cancer , malignant melanoma , prostate cancer , and gynecologic cancers . By integrating human tumor sample analysis with experimental cell and animal models, his team aims to enhance the clinical utility of biomarkers in predicting aggressive tumor behavior and guiding personalized treatment strategies. The recent publications highlight a consistent focus on tumor microenvironment, immune biomarkers, imaging mass cytometry, AI in diagnosis, and age-related phenotypes in cancer. There is a strong trend towards high-dimensional spatial profiling and integration of molecular and clinical data to refine prognostic and predictive models. Lars Andreas Akslen has no listed scientific awards in the provided text. He leads the Tumor Biology Research Group (established in 1995) and the CCBIO center, indicating significant mentorship and leadership in cancer research. While specific students are not listed, his extensive collaboration network suggests active supervision of PhD and postdoctoral researchers. No specific grants are mentioned, but leadership of a national research center implies substantial funding acquisition. He is affiliated with CCBIO and the Tumor Biology Research Group, both based at the Department of Clinical Medicine, University of Bergen, and operating from Haukeland University Hospital. These teams focus on translational cancer biomarker research using advanced molecular and imaging technologies.

• Translational Cancer Research
• Cancer Biomarkers
• Tumor Biology
• +۱۱ مورد دیگر

Joseph Koopmeiners is a Mayo Professor and Division Head of the Division of Biostatistics & Health Data Science at the University of Minnesota School of Public Health. He serves as a Member of the Masonic Cancer Center and Scientific Co-director of the RapidEVAL Program within the Center for Learning Health Systems Sciences. Education: PhD in Biostatistics, University of Washington (2009) MS in Biostatistics, University of Minnesota (2004) BA in Mathematics, St. John's University Koopmeiners develops advanced statistical methods to improve cancer prevention, detection, and treatment through biomarker validation and Bayesian adaptive methods for clinical trials. His research bridges biostatistics with practical applications in oncology, tobacco control, and public health policy. He focuses on innovative trial designs including basket trials, group-sequential methods, and virtual twin approaches that enhance clinical research efficiency. His recent publications demonstrate a strong trend toward adaptive clinical trial methodology, with significant contributions to Bayesian statistics, biomarker validation, and cancer research. Koopmeiners' work spans from fundamental statistical methodology to direct applications in cancer treatment, sepsis management, and tobacco regulation. Awards: Delta Omega, Honorary Society in Public Health Koopmeiners maintains active professional engagement through multiple research collaborations and leadership roles. As Division Head, he oversees biostatistical research and educational programs while directing the RapidEVAL Program focused on learning health systems. His methodological expertise supports numerous clinical trials and public health initiatives across cancer research and other medical domains. His work connects statistical innovation with real-world health applications through the Masonic Cancer Center and Center for Learning Health Systems Sciences, where he contributes to translational research infrastructure.

• Biostatistics
• Cancer Research
• Biomarker Validation
• +۵ مورد دیگر

Vania Ceccato is a Professor at the Academy of Police Work, University of Borås, specializing in environmental criminology and situational crime prevention. She leads the international Nätverket Säkraplatser network, fostering collaboration between academia and practice for sustainable safety. Her research bridges urban design, rural criminology, and transit security, with a focus on inclusive safety measures. Her recent publications include studies on transit worker safety in Stockholm’s metro resilient urban design for climate and crime prevention LGBTQI+ safety in transportation rural-urban shooting patterns innovative survey methodologies Her work aligns with United Nations SDGs 9, 11, and 13, emphasizing how environmental criminology can drive sustainable, equitable urban development.

• Environmental Criminology
• Situational Crime Prevention
• Urban Planning
• +۵ مورد دیگر

Xavier Darzacq is a Professor of Molecular Therapeutics at the University of California, Berkeley, holding the Edward E. Penhoet Distinguished Endowed Chair in Global Health and Infectious Disease. His research at the intersection of molecular biology and biophysics focuses on understanding how nuclear organization governs transcription regulation during cellular differentiation. Research Highlights: Investigates transcriptional control via non-canonical mediator complexes in fibroblast-to-myofibroblast differentiation. Develops advanced imaging techniques (single-molecule tracking, 3D FISH) to study transcription factor mobility and chromatin interactions. Proposes biophysical models where protein diffusion in the nucleus is guided by DNA/chromatin networks. Technological Innovations: Pioneered methods for single-molecule tracking and super-resolution imaging, enabling nanoscale and millisecond-resolution analysis of nuclear processes. Collaborates with experts in biophysics, chemistry, and imaging to integrate multidisciplinary approaches. Scientific Awards: Edward E. Penhoet Distinguished Endowed Chair (Global Health and Infectious Disease) Nature Structural & Molecular Biology – Selected Article of the Month (2007) His lab (http://tjian-darzacq.mcb.berkeley.edu/) explores how nuclear architecture influences gene expression, particularly in wound healing contexts. Future work aims to leverage advancements in microscopy and genome editing to unravel transcriptional rules in living organisms.

• Transcription Regulation
• Nuclear Organization
• Cellular Differentiation
• +۶ مورد دیگر

Kathleen Liddell is the Herschel Smith Senior Lecturer of Intellectual Property Law at the University of Cambridge, where she serves as the Founding Director of the Cambridge Centre for Law, Medicine and Life Sciences and is a member of the Cambridge Centre for IP and Information Law. She holds degrees including a D.Phil from Oxford, LLB (hons) and BSc from Melbourne, and an MBioeth from Monash. With experience in both academic and practical legal settings, including private practice and public sector legal services for a health department, Dr. Liddell brings a comprehensive perspective to her interdisciplinary work at the intersection of law, medicine, and technology. Dr. Liddell's educational background reflects her interdisciplinary approach: D.Phil in Law from the University of Oxford, focusing on regulation of controversial genetic technologies in morally pluralist societies LLB (hons) and BSc from the University of Melbourne MBioeth from Monash University Her research focuses on health, medicine and society, with particular emphasis on intellectual property frameworks that govern medical innovation. Dr. Liddell examines how intellectual property rights both help and hinder the translation of medical discoveries into effective clinical treatments, and how these frameworks could be modified to be more effective and just. She leads international collaborations investigating intellectual property law across five key areas of bioinnovation: pharmaceutical repurposing, antibiotics, biologics, rare diseases, and machine-learning based precision medicine. Her work also addresses legal challenges in pre-mortem interventions for organ transplantation, regulatory gaps in healthcare, and the application of theoretical insights from regulatory and political theory to biomedical controversies. Dr. Liddell employs diverse legal methodologies including statutory and case law analysis, normative analysis drawing on moral philosophy, regulatory theory, empirical investigations (interviews, surveys, patent mapping), and expert meetings. She has made significant contributions to understanding the impact of patent law on life sciences innovation, particularly regarding genetic technologies, precision medicine, and diagnostic tools. Her notable scientific contributions include: Principal investigator for a major research project on intellectual property rights, precision medicine and genomic medicine (2015-2018) International collaborations on intellectual property law in bioinnovation Empirical studies on the impact of patent law on medical innovation Research on regulatory frameworks for emerging health technologies Analysis of legal implications for organ transplantation and antimicrobial resistance Dr. Liddell actively supervises research theses at all levels, including PhD students, and teaches across various courses including Law and Ethics of Medicine, Law, Medicine and Life Sciences, Intellectual Property, and the Law PhD Research Methodologies course. She also serves as a Senior Fellow at the University of Melbourne, teaching 'Law and Emerging Health Technologies.' Her research has significant practical applications, informing policy development in areas such as: Intellectual property frameworks for medical innovation Regulation of diagnostics and pharmaceuticals Legal aspects of precision medicine and genomic medicine Machine learning applications in healthcare Stem cell and regenerative medicine Gene editing technologies

• Intellectual Property Law
• Medical Law
• Bioethics
• +۷ مورد دیگر

Joseph G. Allen is an Associate Professor at Harvard T.H. Chan School of Public Health, where he directs the Harvard Healthy Buildings Program and serves as Deputy Director of the Harvard Education and Research Center for Occupational Safety & Health . He holds leadership roles in major public health initiatives including as Commissioner for The Lancet COVID-19 Commission and Scientific Advisor to the White House (2022-2024). His work bridges environmental health, building science, and public policy to advance human health in indoor environments. Education: D.Sc. in Exposure Assessment, Environmental Epidemiology & Biostatistics – Boston University MPH in Environmental Health – Boston University BS in Biology – Boston College Certified Industrial Hygienist (CIH) Research Focus: Dr. Allen's work centers on indoor environmental quality and its impact on human health. His research examines: 1) Airborne pathogen transmission mitigation strategies, 2) Chemical exposure pathways in built environments, 3) Climate-resilient building design, and 4) Global health equity in environmental interventions. His studies employ field measurements, computational modeling, and epidemiological approaches to develop evidence-based building standards. Publications: His recent 15 publications demonstrate consistent focus on air quality interventions, chemical exposure assessment, and health-focused building design. Key themes include pandemic-responsive ventilation standards, PFAS contamination mitigation, global health equity in environmental interventions, and technological innovations in exposure monitoring. His work appears in both scientific journals and policy-oriented outlets like Harvard Business Review. Awards & Leadership: Scientific Advisor to White House & Massachusetts Governor Chair of Lancet COVID-19 Task Force for Safe Work/Schools/Travel Co-Chair of Harvard Sustainability Committee's 2050 Subcommittee Program Direction: As Director of the Harvard Healthy Buildings Program, Dr. Allen leads interdisciplinary research translating building science into public health practice. The program collaborates with governments and industries worldwide to implement health-focused building standards and exposure reduction strategies.

• Indoor Air Quality
• Healthy Buildings
• Exposure Assessment
• +۳ مورد دیگر

Patricia J. Hilleren is an Associate Professor of Biology and current Department Chair at Skidmore College , Saratoga Springs, NY. Her research focuses on nuclear mRNA quality control systems and gene expression accuracy in eukaryotic cells, using Saccharomyces cerevisiae as a model organism. She earned her PhD in Biochemistry, Molecular Biology, and Biophysics from the University of Minnesota (1997) and completed postdoctoral research at the Howard Hughes Medical Institute, University of Arizona (1997-2003). Education: B.S., Microbiology (1987), St. Cloud State University Ph.D., Biochemistry, Molecular Biology, and Biophysics (1997), University of Minnesota Postdoctoral Research (1997-2003), Howard Hughes Medical Institute, University of Arizona Courses Taught: Liberal Sciences I Molecular Cell Biology (BI 242) Chromatin Structure, Maintenance and Function (BI 360) mRNA Synthesis, Processing, and Turnover (BI 363) Research Interests: Hilleren investigates nuclear quality control systems that ensure accurate gene expression, focusing on how defective pre-mRNAs are recognized, retained at transcription sites, and removed in eukaryotic cells. Her work addresses fundamental cellular mechanisms through yeast genetics and molecular biology approaches. Publication Trends: Her research spans RNA biology, gene expression regulation, and mRNA surveillance systems. Key themes include nuclear RNA processing errors, cytoplasmic degradation pathways, and molecular mechanisms of mRNA quality control in Saccharomyces cerevisiae . Contact: Office: Biology Department - CIS 210A Phone: (518) 580-8301 Email: phillere@skidmore.edu Office Hours: Tuesdays 10:30am-12noon, Thursdays 2:15pm-3:30pm

• Molecular Biology
• Biochemistry
• RNA Biology
• +۵ مورد دیگر

Professor Margaret Ashcroft is a Principal Investigator at the University of Cambridge, Department of Medicine, and affiliated with the Cambridge Immunology Network. Her research focuses on hypoxia signaling, mitochondrial biology, and their roles in cancer, angiogenesis, ischemia, and metabolism. Institution: University of Cambridge Department: Department of Medicine Research Trends: Her recent work explores mitochondrial gene regulation (e.g., CHCHD4) in tumour growth, hypoxia-induced metabolic adaptations, and HIF signaling in both cancer and viral contexts. Studies include ischemic tolerance mechanisms and mitochondrial disulfide relay systems. Scientific Focus: Key subfields include tumour cell viability under hypoxia, epithelial-mesenchymal transition, and hypoxia's role in viral replication (e.g., HIV). Her publications emphasize translational immunology and metabolic homeostasis.

• Angiogenesis
• Hypoxia
• Ischaemia
• +۶ مورد دیگر

Dominick Gamache, Ph.D. serves as an Associate Professor at the Université du Québec à Trois-Rivières, working as a Psychologist with research focused on Clinical and Cognitive Neuroscience. His institutional affiliation includes office space at the Centre de traitement le Faubourg Saint-Jean and contact through dominick.gamache@uqtr.ca. Dr. Gamache's research centers on personality disorders with particular emphasis on evaluation and treatment methodologies. His work examines premature treatment dropout in patients with personality disorders, leading to the development of the Treatment Attrition-Retention Scale for Personality Disorders. He investigates variables associated with therapeutic relationships including alliance, collaboration, transference, and counter-transference during psychodynamic psychotherapy. Additionally, he has launched a significant research program examining stalking behaviors in young adult love relationships. His methodological contributions include developing and validating measures of psychodynamic variables such as personality organization and transference. Analysis of his recent publications (2022-2025) reveals a strong focus on the DSM-5 Alternative Model for Personality Disorders across multiple research domains. His work spans clinical applications, forensic contexts (particularly stalking behaviors), relationship dynamics, and psychometric validation. The research demonstrates interdisciplinary approaches combining clinical psychology, cognitive neuroscience, and forensic psychology with consistent methodological rigor in scale development and validation. Dr. Gamache maintains an active research program with numerous collaborative projects, evidenced by his extensive publication record in high-impact journals including Journal of Personality Disorders, Journal of Personality Assessment, and Frontiers in Psychiatry. His work bridges theoretical psychodynamic concepts with empirical validation, contributing significantly to personality disorders research and clinical practice.

• Personality disorders
• psychodynamic therapy
• therapy dropout
• +۳ مورد دیگر

Ritwick Sawarkar is a Principal Investigator at the MRC Toxicology Unit and affiliated with the Department of Genetics under the School of Biological Sciences at the University of Cambridge. He leads the Sawarkar Group, focusing on molecular mechanisms linking chromatin biology, environmental stress response, and transcriptional regulation. Education: PhD in Genetics (Indian Institute of Science, 2010) Previous roles: Postdoctoral Fellow at ETH-Zürich (2010-2014), Independent Group Leader at Max Planck Institute (2014-2019) Research Interests : The Sawarkar Group investigates how chromatin interprets environmental stress signals to modulate transcriptional responses. Key questions include: (i) Cellular pathways sensing stress/toxins, (ii) Chromatin's role in stress adaptation, and (iii) Transcriptional mechanisms for cellular survival. Their work integrates genomics, single-cell transcriptomics, proteomics, and mouse models to explore stress response pathways. Article Trends : Recent publications highlight his expertise in chromatin-mediated stress responses, non-coding RNA interactions, and proteostasis networks. Collaborations with pharmaceutical companies emphasize translational applications for drug toxicology and RNA therapeutics. Scientific Awards : ERC Consolidator Grant (2018) Alfred Tissières Young Investigator Award (2019) Group Members : His team includes PhD students (Dimitris Aspri, Roberto Campalastri), Research Associates (Simone Baldan, Christo Christov), and MPhil students (Anfas Muhammed, Keely Xia), among others.

• Chromatin Biology
• Environmental Stress Response
• Transcriptional Regulation
• +۳ مورد دیگر

Dr. Margie Peden is a distinguished public health researcher specializing in injury prevention, currently holding multiple academic and leadership positions. She serves as a Senior Research Fellow at Imperial College London's School of Public Health, Faculty of Medicine, and as a Conjoint Senior Lecturer at the University of New South Wales, Sydney. Additionally, she holds an honorary position at Johns Hopkins University and serves as Head of Global Injury at The George Institute for Global Health, where she is also Co-director of the WHO Collaborating Centre on Injury Prevention. Dr. Peden's research interests focus on preventing unintentional injuries, particularly in resource-limited settings. Her work spans road traffic injuries, drowning prevention, burns, falls, and the intersection of alcohol use with injury risk. She has a particular emphasis on developing and evaluating interventions for child injury prevention in low-income countries and improving emergency care systems, especially through enhancing nurses' capabilities in accident and emergency units. Her methodological approach often incorporates participatory research techniques to develop effective practices for society's most vulnerable populations. Throughout her career, Dr. Peden has produced an extensive body of scholarly work, with recent publications focusing on child injury prevention in African contexts, road safety policy analysis, and methodological approaches to measuring injury prevention effectiveness. Her research demonstrates a consistent focus on translating evidence into practical interventions that can be implemented in resource-constrained settings. Dr. Peden plays significant roles in global road safety initiatives, including serving on the Commonwealth Road Safety Initiative Expert Panel and chairing the Global Advisory Board for the Malawi Road Safety Research and Implementation Unit. She previously coordinated the Unintentional Injury Prevention team at WHO for 17 years, where she served as executive editor for major WHO reports on road traffic injury and child injury prevention. Her professional journey began with a decade of work as an ICU nurse in South Africa before transitioning to epidemiology and public health research. She holds a PhD from the University of Cape Town and has maintained a strong connection to both clinical practice and academic research throughout her career.

• Injury Prevention
• Road Traffic Safety
• Child Injury Prevention
• +۷ مورد دیگر

Paula Goforth is an Assistant Professor at the University of Michigan Medical School , affiliated with the Department of Pharmacology and the Caswell Diabetes Institute . Her research focuses on the intersection of neuropharmacology and metabolic disease, particularly leptin signaling, orexin regulation, and hypothalamic circuits controlling glucose homeostasis and energy balance. Education: Postdoctoral training at Virginia Commonwealth University School of Medicine (2000-2004), specializing in Pharmacology under Dr. Satin LS. Her work explores neuron-specific metabolic regulation , including calcium channel modulation in obesity, orexin-glucose axis dynamics, and GABA-independent hypothalamic signaling. She employs techniques such as cell-type-specific circuit dissection and synaptic physiology to study these mechanisms. Recent publications highlight her expertise in leptin-regulated pathways , area postrema neuron function , and traumatic brain injury-related receptor changes , with implications for diabetes, obesity, and neurodegenerative diseases. Scientific Awards: NIH grants spanning 2013-2029, including dual awards for leptin action and gut-brain axis research Industry collaborations with Eli Lilly, Pfizer, and MedImmune LLC University of Michigan institutional support for diabetes/metabolic research Dr. Goforth's laboratory investigates metabolically coupled ion channels and neuronal population dynamics in metabolic disease models, with a strong emphasis on translational neuroscience applications.

• Neuropharmacology
• Metabolic Disease Research
• Neuroendocrinology
• +۵ مورد دیگر

Christopher Vakoc is a Professor at Cold Spring Harbor Laboratory (CSHL), holding the Alan and Edith Seligson Professorship of Cancer Research and serving as Deputy Director of the Cancer Center. His work focuses on understanding how epigenetic dysregulation contributes to cancer pathogenesis, with particular emphasis on epigenetic dependencies and lineage plasticity. Dr. Vakoc's research investigates how transcription factors and chromatin regulators control gene expression in cancer cells. His lab employs high-throughput CRISPR-based genetic screens to identify critical epigenetic regulators in specific cancers. A significant finding from his work demonstrated that blood cancers are often vulnerable to targeting transcriptional coactivators like BRD4 and the SWI/SNF chromatin remodeling complex. His team showed that BRD4 inhibition has therapeutic effects in leukemia mouse models, leading to ongoing clinical trials. Analysis of Vakoc's recent publications reveals a strong focus on pancreatic cancer mechanisms, particularly basal-like identity and lineage plasticity. His work on the MED12-ΔNp63 interaction in pancreatic cancer represents a major breakthrough in understanding how cancer cells lose their original identity. Additionally, his research spans acute myeloid leukemia, sarcoma, lung cancer, and glioma, with consistent themes of epigenetic regulation and identification of novel therapeutic targets. Scientific awards recognizing his contributions include: Paul Marks Prize for Cancer Research AACR Outstanding Achievement in Cancer Research Award Pershing Square Sohn Prize Long Island Excellence in Healthcare Award (2023) Burroughs Welcome Fund Career Award for Medical Scientists Dr. Vakoc actively mentors numerous graduate students and postdoctoral fellows, with several former trainees now holding prominent positions in academia and industry. His research is supported by multiple grants including funding from the National Cancer Institute, Pershing Square Sohn Cancer Research Alliance, and National Institutes of Health. The Vakoc Laboratory serves as a hub for innovative cancer epigenetics research, employing cutting-edge CRISPR screening technologies to reveal new therapeutic opportunities across multiple cancer types.

• Cancer Epigenetics
• Transcription Factors
• Chromatin Regulators
• +۷ مورد دیگر

Dr. Mazen Kheirbek is a Professor in Psychiatry at the University of California, San Francisco (UCSF) School of Medicine. He leads research at the Kheirbek Lab, focusing on hippocampal circuits in emotional behavior and psychiatric disorders. Education : BA (Washington University), PhD (University of Chicago), Postdoc (Columbia University) Research Interests center on: Neural circuits in anxiety and depression Hippocampal-prefrontal pathways Adult neurogenesis mechanisms Neuroplasticity in mood disorders Optogenetics and circuit mapping Translational psychiatry Publication Trends show consistent contributions to neuroscience journals, particularly in hippocampal function, neural circuits, and psychiatric disorders. His work often employs animal models and advanced imaging techniques. Scientific Awards : McKnight Foundation Memory & Cognitive Disorders Award (2020) Pew Scholar in Biomedical Sciences (2019) Klingenstein-Simons Fellowship (2019) Human Frontier Science Program Young Investigator (2019) NARSAD Young Investigator Award (2012) Grants include multiple NIH-funded projects: NIH/NIDA 1R01DA062018 (2025-2030): Dopaminergic circuits in insight learning NIH/NIMH 1R01MH136270 (2025-2030): Hippocampal stimulus processing NIH/NIDCD R01DC19813 (2021-2026): Dentate gyrus associative learning

• Neuroscience
• Neurology
• Psychiatry
• +۴ مورد دیگر

Yulia Y Tyurina serves as a Research Professor in the Department of Environmental and Occupational Health at the University of Pittsburgh. Her research focuses on the fundamental role of phospholipids and their oxygenated species in cell death pathways including apoptosis, necroptosis, ferroptosis, and mitophagy. She discovered that cardiolipin oxygenated species are essential for apoptotic execution and serve as an 'eat-me' signal for mitochondrial quality control via mitophagy. Dr. Tyurina's educational background includes: 1988: Master of Biochemistry from Saint Petersburg State University, Saint Petersburg, Russia 1995: PhD in Biochemistry from the Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Science, Saint Petersburg, Russia Her research program centers on redox lipid signaling mechanisms in cell death. She has demonstrated that phospholipid peroxidation drives ferroptosis through complex oxidation signatures and identified key roles for 15-lipoxygenase products. This work bridges basic biochemistry with translational applications in cancer, neurodegeneration, and inflammatory diseases, revealing how lipid oxidation products function as death signals across diverse biological contexts. Analysis of her 15 most recent publications (2020-2022) shows consistent focus on lipid peroxidation in ferroptosis across multiple disease models. Her work spans from cyanobacterial cell death to human pathologies including lung injury, SARS-CoV-2 complications, and cancer, with recurring mechanistic themes involving 15-lipoxygenase, cardiolipin oxidation, and mitochondrial dysfunction. Methodologies include advanced lipidomics, molecular imaging, and genetic models. Scientific awards were not mentioned in the provided information. Details about student advising and grant funding were not provided in the available text. Dr. Tyurina operates within a prominent redox biology research group led by Dr. Valerian E. Kagan at the University of Pittsburgh, maintaining extensive collaborations across departments and institutions as evidenced by her co-authorship network spanning immunology, oncology, and infectious disease research.

• Cell Death Pathways
• Lipid Peroxidation
• Ferroptosis
• +۴ مورد دیگر