جستجوی استاد راهنمای دانشگاهی

Lene Uhrbomمشاهده پروفایل

استاد

• Neuro-oncology
• Glioblastoma research
• Molecular cancer biology
• +۵ مورد دیگر

Lene Uhrbom is Professor of Molecular Brain Tumor Research at Uppsala University's Department of Immunology, Genetics and Pathology within the Faculty of Medicine. She leads the Neuro-oncology and Neurodegeneration Research Programme and maintains an active research group focused on glioblastoma mechanisms. Her team includes PhD students Veera Jokinen and Ines Neves, Master's student Ellen Rahmqvist, doctoral assistant Xi Lu, and research assistant Rebeca-Noemi Imbria. Her research centers on neuro-oncology with emphasis on glioblastoma stem cells, molecular mechanisms of tumorigenesis, and cell-of-origin studies. She investigates how epigenetic regulation, signaling pathways, and tumor microenvironment interactions drive glioma development and therapeutic resistance. Her work bridges basic molecular biology with translational applications for improved diagnostics and treatments. Analysis of her 15 most recent publications reveals a strong focus on molecular subtyping of glioblastoma, stem cell biology, and therapeutic targeting. Her research consistently explores how cellular lineage, epigenetic regulation, and microenvironmental factors create distinct tumor subgroups with different clinical outcomes. Recent work has expanded into vascular biology, immunotherapy, and advanced imaging techniques for tumor detection. Professor Uhrbom has received significant recognition for her work, with publications in high-impact journals including Nature Communications, Cancer Cell, and Journal of Clinical Investigation. Her research has been featured in multiple news outlets, cited in patents, and referenced in Wikipedia, demonstrating its broad scientific impact. Her laboratory maintains an extensive collection of patient-derived glioblastoma models and employs advanced techniques including single-cell sequencing, epigenetic profiling, and sophisticated mouse models. Current projects focus on developing targeted therapies based on molecular subtyping and improving drug delivery across the blood-brain barrier. She actively collaborates with clinical neuro-oncology teams to translate basic findings into potential therapeutic strategies.

• Reproductive Biology
• Endometriosis Research
• HPV and Cervical Cancer
• +۴ مورد دیگر

Matts Olovsson is a Professor at the Department of Women's and Children's Health, specializing in Reproductive Biology at Uppsala University. His work focuses on women's reproductive health, with particular emphasis on endometriosis, HPV-related conditions, and the impact of environmental factors on reproductive systems. His research interests include: Endometriosis and its impact on women's health and quality of life HPV testing, cervical dysplasia, and cervical cancer prevention Effects of endocrine disrupting chemicals on reproductive health Reproductive toxicology and environmental impacts on fertility Women's health outcomes and patient-centered care approaches Professor Olovsson's recent publications demonstrate a strong focus on longitudinal studies using Swedish registry data, in vitro models to study endocrine disruptors, and clinical investigations into women's reproductive conditions. His work spans molecular biology, epidemiology, and clinical gynecology, with particular attention to how environmental factors influence reproductive outcomes. His scientific contributions include: Research on HPV testing methodologies and their effectiveness as tests of cure Studies on the impact of phthalates and other chemicals on endometrial function Investigations into endometriosis diagnosis, treatment, and quality of life impacts Analysis of hormonal contraceptive effects on reproductive health outcomes Examination of vaginal microbiota composition in relation to cervical dysplasia Professor Olovsson maintains active clinical and research collaborations within the Uppsala University Hospital system and participates in numerous national and international research initiatives focused on improving women's reproductive health outcomes through both basic science and clinical research approaches.

Patrik Rydénمشاهده پروفایل

استاد

• Mathematical Statistics
• Data Analysis
• Ambulance Care Optimization
• +۳ مورد دیگر

Patrik Rydén is a Professor of Mathematical Statistics at the Department of Mathematics and Mathematical Statistics, Umeå University, where he applies statistical methods to complex datasets. He also directs the Industrial Doctoral School for Research and Innovation , fostering academia-industry collaboration. His research spans healthcare (ambulance logistics, cancer diagnostics), industrial optimization (automotive quality control), and bioinformatics. Research Focus Rydén develops data-driven methodologies for: Healthcare : Optimizing ambulance deployment, predicting patient care times, and modeling disease spread. Industry : Statistical process control for manufacturing and quality improvement. Bioinformatics : Cancer subtype identification and vaccine efficacy modeling. Publication Trends His recent work emphasizes applied statistics in healthcare (40%), industrial machine learning (30%), and genomic analysis (30%), with strong themes in predictive modeling, spatio-temporal analysis, and high-dimensional data interpretation. Leadership & Projects As director of the Industrial Doctoral School, he bridges academic research with industry needs. Key projects include: Predicting post-anesthesia care time using ML (2022–2027) Data-driven prehospital care optimization (2018–2028) Statistical learning for industrial defect detection (2017–2023)

• Molecular Biology
• Developmental Biology
• Evolutionary Biology
• +۳ مورد دیگر

Tatjana Haitina is a Researcher at the Department of Organismal Biology; Evolution and Development at Uppsala University. She holds a PhD and Docent title, with an ORCID identifier 0000-0002-8754-5534. Her research focuses on the regulatory mechanisms and 3D organization of skeletal tissues during vertebrate development and evolution, particularly studying skeletal joints, connective tissues, and mineralized structures using zebrafish as a primary model. Her academic background includes a doctoral thesis on 'Function, Pharmacology, Evolution and Anatomical Localization of G Protein-Coupled Receptors and Solute Carriers' (2009). She has contributed chapters to books such as 'Odontodes' (2023) and 'Evolving Neural Crest Cells' (2020). Research interests span molecular evolution of genes and regulatory sequences, CRISPR-Cas9 genome editing, and 3D microstructure analysis of mineralized tissues. Recent work includes studies on craniofacial development, sensory organ evolution in sharks, and cis-regulatory elements in lymphatic vascular beds. Her publications highlight collaboration with institutions globally, with notable contributions to journals like Nature Communications and Molecular Biology and Evolution. No scientific awards are explicitly listed, though her work has been cited widely. Dr. Haitina's lab employs cutting-edge imaging techniques such as synchrotron X-ray microtomography and optical projection tomography (zOPT) to study developmental defects in zebrafish mutants. She investigates ancestral features of skeletal mineralization and the evolutionary origins of enamel.

Trung Nghia Vuمشاهده پروفایل

پژوهشگر

• Bioinformatics
• Computational Biology
• Cancer Genomics
• +۵ مورد دیگر

Trung Nghia Vu is a Principal Researcher at the Department of Medical Epidemiology and Biostatistics at Karolinska Institutet in Stockholm, Sweden. His research group focuses on developing and applying statistical and bioinformatics methods for molecular biology and medicine, with particular emphasis on cancer genomics and pharmacogenomics. Dr. Vu received his PhD from the Department of Mathematics and Computer Science at the University of Antwerp, Belgium (2009-2014), following an MSc in Computer Engineering from Korea Aerospace University (2006-2008) and a BSc in Technology from Vietnam National University in Hanoi (2000-2004). His research focuses on developing statistical and bioinformatics methodologies for analyzing high-throughput omics data, with specific interests in single-cell sequencing analysis, characterization of cancer omics, and pharmacogenomics. His group has developed 20 statistical and bioinformatics tools available through Biostat Wiki Primary research areas include gene/isoform quantification, detection of abnormal RNAs, single-cell RNA-seq analysis, and drug response prediction Current projects focus on breast cancer and Acute Myeloid Leukemia (AML) Analysis of Dr. Vu's recent publications reveals a strong focus on cancer genomics, particularly in AML and breast cancer. His work bridges computational biology with clinical applications, developing methods for spatial transcriptomics, drug synergy prediction, and circular RNA analysis. The research demonstrates a clear trajectory toward precision medicine applications, with increasing emphasis on personalized drug response prediction and pathway activation modeling. Dr. Vu actively supervises multiple students and researchers, including both completed PhD students (Quang Thinh Trac, Lu Pan, Wenjiang Deng) and ongoing supervisees (Gulser Caliskan, Meghana Alugunoolla, Yuying Li, Aron Arzoomand). His research is supported by significant grants from the Swedish Research Council, CancerFonden, and Karolinska Institutet. He leads the Computational Medicine and Bioinformatics research group at Karolinska Institutet, which collaborates with international clinical and systems-biology researchers. The group maintains active development of bioinformatics tools and maintains the Biostat Wiki platform for academic use. Dr. Vu also contributes to teaching through master's and doctoral courses in biostatistics and R programming at Karolinska Institutet.

• Cancer and Oncology
• Hematology
• Transcriptional Regulation
• +۳ مورد دیگر

Urban Gullberg is a Professor at Lund University , affiliated with the Faculty of Medicine and the Division of Hematology and Clinical Immunology . He leads the research team on Transcriptional mechanisms for the Wilms’ tumor gene 1 (WT1) oncoprotein at the Lund University Cancer Centre (LUCC), focusing on the role of WT1 in leukemia pathogenesis. Research areas: Genome-wide binding of WT1 isoforms/mutants, transcriptional repression of tumor suppressors (e.g., IRF8), and mechanisms of leukemic cell proliferation. Methods: ChIP-Seq, promoter reporter assays, molecular profiling, and computational deconvolution of gene expression. Key findings: WT1 mutations disrupt transcriptional regulation, contributing to leukemia; identification of co-factors like ZNF224 and therapeutic targets. His work aligns with UN Sustainable Development Goals for cancer research. He supervises PhD students and participates in educational activities related to medical cell biology and targeted therapies.

Anna Hagström-Anderssonمشاهده پروفایل

مدرس ارشد

• Leukemia
• MLL Gene Rearrangements
• Epigenetics
• +۵ مورد دیگر

Anna Hagström-Andersson is a Senior Lecturer at the Division of Clinical Genetics , Lund University , and a Principal Investigator at the Lund University Cancer Centre (LUCC) . She leads research teams focused on the pathogenetic mechanisms of MLL-rearranged acute leukemia in infants , aiming to improve therapeutic approaches through genomic and epigenetic studies. Her research employs high-resolution genomic methods and murine models to investigate genetic lesions , clonal cooperation , and relapse dynamics in pediatric leukemia. She contributes to UN Sustainable Development Goals related to Cancer and Oncology and Basic Cancer Research . Current Projects : "Spädbarn och leukemi: första mekanismerna bakom leukemogenes tidigt i livet" (Swedish Childhood Cancer Fund, 2025–2027) "The molecular pathogenesis of KMT2A-rearranged leukemia from diagnosis to relapse" (Cancerfonden, 2024–2027) Supervision of PhD candidate M. Pilheden on genome-wide MLL-gene rearrangement studies Research Outputs : 49 publications, including groundbreaking work on clonal evolution , metabolic vulnerabilities , and epigenetic regulation in leukemia. Collaborations : Active in LUCC networks and experimental highlight series seminars.

Olga Ortega-Martinezمشاهده پروفایل

پژوهشگر

• Molecular Biology
• Developmental Biology
• Stem Cell Research
• +۷ مورد دیگر

Olga Ortega-Martinez is a Researcher at the Department of Marine Sciences , University of Gothenburg. As an EMBO Fellow , her work focuses on molecular and developmental biology , stem cell behavior , and regeneration mechanisms in marine organisms, particularly echinoderms . Her research explores gene regulatory pathways shared between embryonic development and adult regeneration, with implications for chordate evolution . Institution: University of Gothenburg Department: Marine Sciences Email: olga.ortega-martinez@marine.gu.se Current projects investigate biomineralization and cell lineage regulation in brittlestars ( Amphiura filiformis ), integrating genomics and molecular biology to understand regenerative capacity and environmental stress adaptation . Her group examines how ocean acidification disrupts developmental pathways, linking these findings to global ecological challenges. Scientific contributions include studies on: Brittlestar genome (2024) - Echinoderm regeneration genomics Chondroitin sulfate roles (2017) - Glycobiology in regeneration Environmental stress impacts (2014, 2010) - Ocean acidification effects Marine population genetics (2022, 2023) - Ecotype differentiation Publications span marine molecular biology , regenerative medicine , and environmental genomics . Her work bridges fundamental developmental biology with applied climate change research , using advanced transcriptomic and proteomic techniques to analyze gene expression during regeneration and stress adaptation.

Oliver Billkerمشاهده پروفایل

استاد

• Malaria Research
• Parasitology
• Molecular Biology
• +۵ مورد دیگر

Oliver Billker is a Professor at the Department of Molecular Biology, Umeå University, and serves as Manager of the Molecular Infection Medicine Sweden (MIMS) research group. His research focuses on understanding the biology of malaria parasites and their interactions with mosquitoes, particularly investigating genetic mechanisms and transmission pathways. His work combines cutting-edge genomic tools, CRISPR screening, and single-cell technologies to uncover new insights into parasite development and host-pathogen interactions. Research interests include malaria parasite genetics, drug resistance mechanisms, mosquito vector biology, and the application of genomic approaches to identify novel drug and vaccine targets. Key achievements include the discovery of essential genes for transmission and the development of high-throughput genetic screening platforms for Plasmodium species. Notable awards include the Hirsch Prize and election as EMBO Member. His lab, the Oliver Billker Lab, collaborates internationally to advance malaria research. Recent grants include multi-million SEK investments for basic research at Umeå University and contributions to global initiatives like the Malaria Cell Atlas. Awards: Hirsch Prize EMBO Membership Grants/Projects: VR funding for basic research (2024) Nordic collaboration grants Malaria Cell Atlas initiative Labs/Teams: Oliver Billker Lab Molecular Infection Medicine Sweden (MIMS) His research bridges fundamental biology and translational medicine, aiming to combat malaria through innovative approaches in genomics and systems biology.

• Microfluidics
• Point-of-Care Diagnostics
• Cell Analysis
• +۲ مورد دیگر

Aman Russom is a Professor in Clinical Microfluidics at KTH Royal Institute of Technology. His research group develops microfluidic technologies for point-of-care diagnostics, focusing on cell handling, analysis, and separation techniques for biomedical applications. The group works at the intersection of nanotechnology, fluid dynamics, and biomedical engineering to create advanced lab-on-chip systems. Research interests center on developing miniature laboratories for complex biochemical analyses, particularly for blood samples. Key areas include: Automated cell picking and separation techniques Elasto-inertial focusing of nanoparticles Acoustofluidic methods for environmental monitoring Diagnostic platforms for resource-limited settings Recent publications show strong trends in diagnostic microdevice development, with innovations in fiber-based systems, smartphone-integrated platforms, and multiplexed detection methods. Work consistently addresses clinical translation challenges through surface engineering, 3D tracking, and signal enhancement strategies. The group maintains active collaborations with clinical partners and focuses on creating real-world solutions for healthcare and environmental monitoring.

Colum Walshمشاهده پروفایل

استاد

• Immunology
• Epigenetics
• Mental Health
• +۳ مورد دیگر

Colum Walsh is a Professor at Linköping University's Department of Biomedical and Clinical Sciences (BKV), affiliated with The Division of Cell and Neurobiology (CNB) and SciLifeLab Linköping. His research focuses on immunology, epigenetics, mental health, and genetics, with particular emphasis on immune responses to viral infections, epigenetic regulation in development, and mental health epidemiology among student populations. He contributes to national research initiatives like the Precision Omics Initiative Sweden (PROMISE), integrating genomic and clinical data. Key research areas include T cell memory profiling in SARS-CoV-2 patients, epigenetic effects of nutritional interventions during pregnancy, and biomarker discovery for disease severity prediction. His work bridges basic science and clinical applications, addressing topics from cellular senescence mechanisms to the impact of exercise on epigenetic aging markers in muscle tissue. Collaborations involve multidisciplinary teams across Swedish academic institutions. Recent publications highlight contributions to understanding Omicron variant immune dynamics, folic acid's role in neurocognitive development, and miRNA regulation in prostate cancer. While no specific awards are listed, his active research portfolio reflects sustained academic engagement in high-impact areas of biomedical science.

• Dermatology
• Psoriasis Research
• Inflammation and Immune Mechanisms
• +۳ مورد دیگر

Mona Ståhle is a Professor at Karolinska Institutet, affiliated with the Department of Medicine, Solna. She leads the research group led by Kilian Eyerich and specializes in dermatology, particularly psoriasis and its comorbidities. Her work integrates epidemiology, genetics, and immunology to understand disease mechanisms and improve clinical outcomes. Key research themes include psoriasis-associated cardiovascular risks, biomarker discovery, and the evaluation of biologic therapies. Dr. Ståhle holds a Docent title from Karolinska Institutet (1994) and has contributed to over 200 peer-reviewed publications. Her research emphasizes translational science, bridging basic biology with clinical applications. Education: Docent, Karolinska Institutet (1994). Research Interests: Psoriasis pathogenesis and comorbidities Inflammatory skin diseases Biomarker development Genetic and epigenetic drivers of skin disorders Advising & Grants: While specific student names aren’t listed, her research group collaborates internationally on projects funded by grants focused on dermatology and inflammation. Recent studies involve register-based analyses of psoriasis outcomes and novel treatment approaches. Labs/Teams: Member of the Kilian Eyerich research group, focusing on skin immunology and precision medicine.

• Bioinformatics
• Computational Biology
• Single-Cell RNA Sequencing
• +۶ مورد دیگر

Christoph Ziegenhain is an Assistant Professor at the Karolinska Institute , affiliated with the Department of Medical Biochemistry and Biophysics . He leads the Ziegenhain Lab , which focuses on molecular processes in human cells, particularly the control of alternative splicing in transcribed mRNAs. His group integrates novel single-cell sequencing techniques with computational biology to advance understanding in these areas. Position: Assistant Professor Institution: Karolinska Institute Department: Medical Biochemistry and Biophysics Lab: Ziegenhain Lab Christoph Ziegenhain's research spans Bioinformatics , Computational Biology , and Single-Cell RNA Sequencing . His work emphasizes transcriptional dynamics , alternative splicing , and the development of high-throughput sequencing methods like Smart-seq3xpress and Prime-seq . Current projects analyze gene expression noise, allelic imbalance, and the role of long noncoding RNAs in regulation. The Ziegenhain Lab's recent publications demonstrate expertise in single-cell transcriptomics , multi-omics profiling , and method development for RNA sequencing. Key subfields include transcriptional bursting , redox signaling , epithelial homeostasis , and hematopoietic stem cell differentiation . Swedish Research Council Grant (2023–2026): "Decoding the interplay of regulation and stochasticity in alternative mRNA splicing" Lab members include doctoral students Shiyao Chen and Constantin Diekmann , research assistants Cleo Damon , Zhouhui Qi , and Lukas Schertler , and affiliated researchers such as Gandolfo Gennaro and Ursa Zevnik . Collaborations with institutions like New York University and Stanford University highlight his interdisciplinary approach.

• HPV-associated cancers
• Molecular virology
• Machine learning
• +۶ مورد دیگر

Sara Arroyo Muhr is a Senior Research Specialist and Docent at the Karolinska Institutet , affiliated with the Department of Clinical Science, Intervention and Technology and the Center for Cervical Cancer Elimination . She serves as Scientific Lead at the International HPV Reference Center and coordinates global HPV diagnostic initiatives through the Global HPV LabNet . Education : PhD from Karolinska Institutet (2016), Docent (2025) Her research spans HPV-associated cancers , molecular virology, machine learning applications in cancer prevention, and microbiome interactions in cervical carcinogenesis. She leads Sweden’s cervical cancer elimination project and self-sampling programs in conflict zones like Ukraine. Her work integrates next-generation sequencing and bioinformatics to address diagnostic challenges in HPV testing. Recent publications highlight advancements in HPV genotyping software (HPV-KITE) , quality assurance for HPV DNA testing, microbiome analysis in cervical and anal cancers, and vaccine immunogenicity studies. Key collaborations include international proficiency trials for HPV diagnostics and large-scale registry-based cervical screening research. Teaching roles include lecturing in molecular diagnostics , genomics , and antiviral drugs at undergraduate and graduate levels, alongside PBL tutoring and supervision of five PhD students. She also develops online educational resources for the International HPV Reference Center.

Ali Mirazimiمشاهده پروفایل

استاد مدعو

• Viral Hemorrhagic Fevers
• SARS-CoV-2 Research
• Molecular Pathogenesis
• +۵ مورد دیگر

Dr. Ali Mirazimi is an Adjunct Professor at the Department of Laboratory Medicine, Karolinska Institute. His research focuses on molecular pathogenesis of viral hemorrhagic fevers (CCHFV, Ebola) and SARS-CoV-2, including vaccine development, antiviral therapies, and diagnostic tools. Coordinated CCHFVaccine consortium for developing vaccines Leading IMI/H2020 projects on SARS-CoV-2 Established 3D organoid infection models His lab investigates virus-host interactions across human, animal, and tick cells, with recent publications in Nature Communications , Cell , and Nature Microbiology . Key topics include: RNA virus dependencies on host factors Mechanisms of vascular leakage in VHF Programmed cell death during infections Biosafe diagnostic systems for outbreak settings Collaborations include: Prof. Friedemann Weber (Germany) Prof. Josef Penninger (Austria) Prof. Thomas Helleday (Sweden) NIH/NIAID partnerships