جست‌وجوی استاد و پژوهشگر

• Plant Pathology
• Bacteriology
• Bacterial Genetics
• +۵ مورد دیگر

Minna Pirhonen is a Lecturer at the Department of Agricultural Sciences , University of Helsinki. She supervises doctoral students in four programs: Sustainable Use of Renewable Natural Resources, Integrative Life Science, Microbiology and Biotechnology, and Plant Sciences. Docentship in Crop Production Sciences Active Principal Investigator in plant-microbe interaction research ORCID: 0000-0001-5249-563X Her research focuses on plant pathology and bacterial genetics , particularly in potato disease systems. Key areas include microbial biocontrol , genomic characterization of phytopathogens, and transcriptomic analysis of plant-pathogen interactions. Recent work explores phytohormone dynamics during infection phases and taxonomic reclassification of economically significant bacteria. Current projects (2023-2026) address potato disease epidemiology and risk mitigation strategies. She actively participates in international collaborations and has presented at major conferences like Potato Expo and Euphresco Pectobacterium/Dickeya meetings . Her 74 peer-reviewed publications demonstrate sustained contributions to agricultural microbiology since 1986. Research outputs include genomic resources (2022), transcriptomic studies (2024), and taxonomic revisions (2024). She also engages in seed potato farmer training and public science communication .

• Computational Biology
• Biomedical Informatics
• Cancer Research
• +۴ مورد دیگر

Mitro Samuli Miihkinen is a Postdoctoral Researcher and Supervisor in the Doctoral Programme in Integrative Life Science at the University of Helsinki, affiliated with the Finnish Institute of Molecular Medicine. His research spans computational biology, biomedical informatics, and cancer research with a focus on drug repurposing, spatial transcriptomics, and statistical modeling. Institution: University of Helsinki Collaborations: Active in iCAN - Individualized Cancer Medicine Finland flagship program His recent publications highlight interdisciplinary approaches combining mathematical modeling , bioinformatics , and molecular medicine . Key contributions include developing tools for drug repurposing ( RepurposeDrugs ) and spatial cell type identification ( ScType ). Research activities from 2022-2025 show engagement in computational oncology, with 6 publications and participation in 2 projects. He presented at the iCAN retreat 2024 conference as a speaker.

Allan Tainá De Souzaمشاهده پروفایل

پژوهشگر ارشد

• Ecology
• Evolutionary Biology
• Environmental Sciences
• +۳ مورد دیگر

Allan Tainá De Souza is a Postdoctoral Researcher in the Department of Forest Sciences at the University of Helsinki's Faculty of Agriculture and Forestry. He is affiliated with the Ecosystem processes research group under INAR (Integrative Atmosphere-Ecosystem Research). His work spans multiple disciplines including ecology, evolutionary biology, environmental sciences, and computer information sciences. Dr. Souza's research interests focus on ecosystem processes, biodiversity research infrastructure, and the intersection of environmental science with computational approaches. His work demonstrates expertise in ecological network analysis, biodiversity data management, and the application of computational tools to environmental monitoring. Recent projects indicate strong interest in the sustainability aspects of both ecological systems and computational technologies. Analysis of his publication record shows a clear trend toward interdisciplinary research combining ecological field studies with computational and data science approaches. His work frequently addresses challenges in biodiversity research infrastructure, ecosystem monitoring, and the application of novel technologies to traditional ecological questions. The 2025 publications particularly highlight work on fish ecology, biodiversity data networks, cost calculation tools for environmental monitoring sites, and sustainability considerations for large language models. Dr. Souza is actively involved in significant research projects including the European long-term ecosystem research infrastructure (eLTER PLUS) and the Active Digital Twinning project. His external teaching activities include topics on interoperability between datasets, demonstrating his expertise in data integration challenges within environmental research.

• Chemical Safety Assessment
• Safe and Sustainable by Design (SSbD)
• Toxicogenomics
• +۱۲ مورد دیگر

Dr. Angela Serra is a University Lecturer in the Department of Biomedicine at the Faculty of Medicine and Health Technology, Tampere University, Finland. Her research bridges computer science and biomedicine, focusing on data integration, toxicogenomics, and Safe and Sustainable by Design (SSbD) frameworks for chemical and nanomaterial safety assessment. Her primary research interests include chemical safety assessment , knowledge graphs in drug discovery , toxicogenomics , network toxicology , and computational modeling of adverse outcome pathways . She applies advanced data science and systems biology methods to develop innovative, non-animal approaches for evaluating chemical and nanomaterial risks. The recent publications highlight a strong trend toward integrated data frameworks , digital innovation in sustainability , and mechanistic modeling for regulatory science. Her work emphasizes the use of omics data, knowledge graphs, and AI-driven tools to support Safe and Sustainable by Design (SSbD) principles in chemical and material innovation. Dr. Serra is actively involved in EU-funded research, currently serving as a Work Package Leader in the INSIGHT project under Horizon Europe. She contributes to major collaborative efforts such as the PINK and CompSafeNano projects, advancing digital and data-driven approaches in toxicology and sustainability. She has developed several software tools including Nextcast , BMDx , and MaNGA , supporting toxicogenomics analysis, benchmark dose modeling, and QSAR modeling. These tools are publicly available and contribute to open science in computational toxicology.

• Microbiome Research
• Immunology
• Allergy Research
• +۳ مورد دیگر

Harri Alenius is a Research Professor and Research Director at the University of Helsinki, leading Human Microbiome Research within the Department of Human Microbiome Research. He supervises doctoral programs in Integrative Life Science and Microbiology and Biotechnology. His expertise spans microbial ecology, immunology, and nanotoxicology, with focus on skin microbiome dynamics, allergy mechanisms, and nanomaterial health impacts. Key research areas include atopic dermatitis pathophysiology, host-microbe interactions in skin diseases, and transcriptomic analysis of immune responses. He leads major projects like PREVEX (asthma prevention via early-life microbiota) and EU-funded INQUIRE (microbiome-immune homeostasis). Collaborations span international teams in Europe and beyond. Recent work includes identifying cytokine roles in eczema, post-COVID immune changes, and network toxicology models for nanomaterial risk assessment. He has published 151+ peer-reviewed articles and actively engages in media outreach to bridge scientific findings with public understanding. Current grants include €535k EU Horizon Europe funding for microbiome-allergy research (INQUIRE project, 2022–2027) and Academy of Finland support for early-life bacterial exposure studies (PREVEX, 2022–2026). His work integrates omics technologies, systems biology, and clinical studies to advance personalized medicine and environmental health strategies.

Esa Pitkänenمشاهده پروفایل

استاد مدعو

• Machine Learning
• Biomedicine
• Computational Biology
• +۴ مورد دیگر

Esa Pitkänen is a Senior Researcher at the Institute for Molecular Medicine Finland (FIMM) and holds an Adjunct Professorship in the Department of Computer Science at the University of Helsinki. He is actively involved in the Doctoral Programme in Integrative Life Science, supervising doctoral research. His work bridges computational methods with biomedical applications, focusing on machine learning, genomics, and systems biology. His research interests include developing predictive models using neural networks for medical imaging (e.g., amyloid PET analysis), genomic studies of cancer subtypes (e.g., AML and B-cell lymphomas), and bioinformatics tools for variant discovery. He leads projects funded by the Juselius Foundation and the Academy of Finland, emphasizing personalized medicine and translational oncology. Pitkänen’s recent publications highlight advancements in automated medical coding via deep learning, genomic insights into iron metabolism disorders, and single-cell transcriptomic approaches to cancer therapy optimization. His contributions span computational biology, precision medicine, and multi-omics integration in healthcare. He manages the Meilahti Biodata facility and has supervised doctoral student Kaasinen. His work often involves collaborations across disciplines, addressing challenges in liquid biopsy, mutational signatures, and AI-driven diagnostics.

• Molecular Biology
• Biochemistry
• Cell Biology
• +۳ مورد دیگر

Jussi Taipale serves as Professor in the Department of Pathology at the University of Helsinki, Finland, and supervises the Doctoral Programme in Integrative Life Science. With 112 research publications to date, his work bridges molecular biology and clinical cancer research from his Biocenter 2 laboratory. His research focuses on transcriptional regulation mechanisms, oncogene function, and cancer genomics, with particular expertise in structural analysis of transcription factor-DNA interactions and multi-omics approaches to tumor biology. Recent work reveals common pathways across diverse oncogenes and explores interferon signaling in chemotherapy resistance. Analysis of his 2023-2025 publications shows consistent emphasis on cancer mechanisms through structural biology and genomic technologies, with key contributions to understanding MYC regulation, transcription factor specificity, and ovarian cancer pathogenesis published in Nature, Science Advances, and Cell Reports Medicine. Taipale's scientific recognition includes: ERC Advanced Grant (2009) EMBO Young Investigator (2006) Anders Jahre Young Researcher award (2008) Eric K. Fernström's Prize (2010) Medix Prize (2006) He actively mentors doctoral candidates and serves on academic committees including the Finnish Graduate School in Computational Sciences. His grant portfolio features European Research Council funding, and he contributes to peer review for Cell, PNAS, and Genome Research. Current work continues to investigate transcriptional networks in cancer through structural and genomic approaches. Based at Viikinkaari 5 Biocenter 2, his research group maintains international collaborations focused on decoding gene regulatory mechanisms in disease contexts.

• Immunology
• Microbiome Research
• Nanotoxicology
• +۳ مورد دیگر

Piia Karisola is a University Researcher and Human Microbiome Research Supervisor in the Doctoral Programme in Integrative Life Science at the University of Helsinki, Faculty of Medicine. She holds an active ORCID (0000-0003-0635-2704) and manages multiple research projects funded by the Sigrid Jusélius Foundation, European Commission, and Occupational Safety and Health Fund. Her research spans immunology, microbiome, nanotoxicology, and transcriptomics, focusing on environmental impacts (nanoparticles, UV radiation, allergens) on skin and immune responses. Key areas include allergic diseases, contact hypersensitivity, and post-COVID-19 conditions, utilizing molecular biology, bioinformatics, and in vivo models to investigate host-microbe interactions and immune regulation. Recent publications (2023-2025) emphasize nanomaterial safety assessment, skin immunology, and transcriptomic profiling of disease mechanisms. Her work reveals how engineered nanoparticles alter skin/lung immunity, identifies molecular signatures in long COVID and allergic disorders, and explores microbiome-immune crosstalk in health and disease through international collaborations. She currently leads four major projects: Juselius 2024 (€700,000, 2024-2028) on human microbiome research, TSR TORJU (€107,760, 2023-2026) in occupational health, EU/Re-MEND (€249,208, 2023-2027) on nanomaterial safety, and HKU intern hosting. She previously contributed to the EU/INQUIRE project (2022-2027) as a team member. As head of the Human Microbiome Research group, she collaborates with the University of Helsinki's Nanoscience Center and hosts international researchers like Chunying Chen (2016). Her team integrates immunology, toxicology, and bioinformatics expertise to address environmental health challenges through mechanistic and translational studies.

• Developmental neurogenetics
• Genetics
• Developmental biology
• +۴ مورد دیگر

Juha Partanen is a Professor at the Molecular and Integrative Biosciences Research Programme within the Faculty of Biological and Environmental Sciences at the University of Helsinki. His research focuses on developmental neurogenetics , specifically investigating how intercellular communication and gene regulation generate neuronal diversity in the vertebrate midbrain. His work addresses the molecular mechanisms controlling the development of dopaminergic and GABAergic neurons , which are critical for behavior regulation and implicated in psychiatric diseases. Key research themes include Intercellular signaling pathways Transcriptional regulation networks Neuronal progenitor dynamics Neurodevelopmental disorder modeling His recent publications examine hypoxia-responsive gene expression, synovial sarcoma pathogenesis, and amygdala circuit development. Awarded the Medix Prize in 2008 and 2004, Partanen leads multiple funded projects including "Gene regulation in the developing brainstem" (Academy of Finland 2024-2028) and "Hypoxia promotes colorectal cancer" (Magnus Ehrnrooth Foundation 2025-2026). He serves as doctoral thesis supervisor and examiner, and previously chaired the Finnish Society for Developmental Biology (2013-2015).

• Epilepsy
• Traumatic Brain Injury
• Molecular Neuroscience
• +۴ مورد دیگر

Noora Puhakka is a Researcher at the A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, affiliated with the Faculty of Health Sciences. Her work focuses on epilepsy, traumatic brain injury (TBI), biomarker discovery, and molecular mechanisms of epileptogenesis and neurodegeneration. University: University of Eastern Finland Institute: A.I. Virtanen Institute for Molecular Sciences School: Faculty of Health Sciences Role: Researcher Her research interests span molecular neuroscience , neurotrauma biomarkers , and RNA biology , particularly microRNA and tRNA-derived fragments as diagnostic/prognostic indicators for post-traumatic epilepsy. She has contributed to multicenter initiatives like EpiBioS4Rx and EPITARGET , emphasizing procedural harmonization for reproducibility in preclinical studies. Key article trends show a focus on RNA-based biomarkers (2024-2020), neuroinflammation , neurodegenerative pathways , and machine learning applications for seizure liability prediction. Notable collaborative projects include proteomic analysis of lymph nodes post-TBI and NOTCH1 signaling dysregulation in epilepsy. She has co-authored 15 refereed publications (2014-2025) with affiliations to institutions like University of Eastern Finland and collaborations with Asla Pitkänen’s team. Her work involves advanced methodologies such as RNA-Seq, proteomics, and machine learning to analyze drug-induced gene expression changes and develop seizure prediction models.

• Machine Learning
• Differential Privacy
• Bayesian Statistics
• +۳ مورد دیگر

Antti Honkela serves as a Visitor at Aalto University's Department of Computer Science and is deeply affiliated with the Helsinki Institute for Information Technology (HIIT), a joint research institute of Aalto University and the University of Helsinki. Within HIIT, he actively contributes to the Myllymäki Petri research group and leads the Probabilistic Machine Learning research group, focusing on advanced statistical methodologies. His research centers on machine learning with rigorous emphasis on differential privacy, Bayesian statistics, and probabilistic modeling. Honkela bridges theoretical innovation with biomedical applications, particularly in drug sensitivity prediction, genomic analysis, and privacy-preserving data sharing. His work addresses critical challenges in maintaining data utility while ensuring mathematical privacy guarantees for sensitive health information. Recent publications reveal a clear trajectory from foundational privacy mechanisms (e.g., FFT-based accounting) toward efficient biomedical implementations. His 10 publications between 2016-2021 demonstrate consistent output in top venues like Nature Communications and NeurIPS, with growing emphasis on transfer learning and distributed frameworks for real-world healthcare data. Scientific recognition includes: 2001 Year-End Thesis Award from CMCM, Center for Mathematical and Computational Modeling, University of Jyväskylä While specific student counts aren't public, his active research profile suggests ongoing supervision opportunities. Funding appears sustained through HIIT's infrastructure and competitive Nordic research grants, enabling work on privacy-preserving algorithms for genomic and clinical datasets. The Probabilistic Machine Learning group provides a collaborative environment leveraging Aalto University's computational resources and HIIT's interdisciplinary network. Lab activities focus on developing theoretically sound privacy mechanisms with practical biomedical impact, particularly in drug response modeling and genomic data analysis where privacy constraints are critical.

• Nanotechnology
• Bioinformatics
• Molecular Biology
• +۳ مورد دیگر

Shruti Shandilya is a Doctoral Researcher at the Department of Applied Physics, Aalto University, specializing in interdisciplinary research at the intersection of nanotechnology, bioinformatics, and biomedical sciences. Her work spans molecular modeling, oxidative stress studies, and nanomaterial synthesis. Institution: Aalto University Department: Applied Physics Email: shruti.shandilya@aalto.fi Research Interests: Shruti's research focuses on: Nanotechnology: Silver-doped gold nanoclusters and their relaxation dynamics Bioinformatics: Computational modeling for enzyme inhibition and DNA microarray analysis Biomedical Research: Gut microbiota-oxidative stress interactions and mitochondrial protection Publication Trends: Her recent publications (2020-2023) demonstrate expertise in developing nanomaterials for optical applications, computational approaches to molecular design, and investigating oxidative stress mechanisms in neurodegenerative diseases. Collaborations: Co-authored studies with multidisciplinary teams involving experts in materials science (Olli Ikkala), computational molecular design (Outi M.H. Salo-Ahen), and biomedical research (Janne Ruokolainen).

• Biomedical Sciences
• Circadian Rhythms
• Neuropathic Pain
• +۳ مورد دیگر

Manqing Wen is a Doctoral Researcher in the Department of Physiology at the University of Helsinki. Her work focuses on the interplay between circadian rhythms and neuropathic pain following peripheral nerve injury, with an emphasis on transcriptomic changes and pharmacological interventions. Research Interests : Biomedical Sciences Circadian Rhythms Neuropathic Pain Physiology Chronobiotics Transcriptomics Projects : Chronobiotics: Resynchronization of the Body's Internal Circadian Clocks as a Treatment for Nerve Damage Pain (2024–2026), funded by the Academy of Finland. Collaborators include V. Palada, W. Dai, and E. Kalso.

Craig Primmerمشاهده پروفایل

استاد

• Ecology
• Evolutionary Biology
• Genetics
• +۵ مورد دیگر

Craig Primmer is a Professor at the University of Helsinki, affiliated with the Faculty of Biological and Environmental Sciences and the Organismal and Evolutionary Biology Research Programme. His research group uses Atlantic salmon as a model organism to investigate integrative functional genomics, ecological, and evolutionary mechanisms underlying reproductive age diversity and its fitness consequences. Research Focus : Genetic basis of life-history variation, stress tolerance, and ecological-genomic interactions in salmonids Key Techniques : Laboratory-controlled molecular analyses and field studies of wild salmon in northern Finland Recent publications highlight his work on Hippo pathway signaling , vgll3 gene effects , and climate change impacts on salmonid conservation. His research has been funded by the European Research Council (ERC), Research Council of Finland, and Academy of Finland. Scientific Awards : City of Helsinki Science Award (2023) As a supervisor, Primmer contributes to doctoral programs in Integrative Life Science and Wildlife Biology, while also serving as a core facility manager for Wild Animal Phenotyping infrastructure.

Thomas McWilliamsمشاهده پروفایل

دانشیار

• Neuroscience
• Molecular Biology
• Cell Biology
• +۷ مورد دیگر

Dr. Thomas McWilliams is an Associate Professor in the Department of Anatomy at the University of Helsinki, where he serves as Principal Investigator of the McWilliams Lab. He holds the title of Docent in Neurobiology and is an Academy of Finland Research Fellow. His work focuses on mitochondrial medicine and autophagy pathways, with particular emphasis on their roles in neurological health and disease. He supervises doctoral students in the Brain & Mind program and collaborates extensively with international research teams. Dr. McWilliams' research interests span multiple interconnected fields: Neuroscience, with focus on Parkinson's Disease, dopaminergic neurons, and neurodegeneration Molecular and cellular mechanisms of autophagy and mitophagy Mitochondrial signaling and organelle crosstalk in mammalian tissues Molecular genetics of cellular degradation pathways Metabolism and its regulation in neuronal health and disease His laboratory employs advanced molecular cell biology, biochemistry, and microscopy techniques using primary mouse neurons, human iPS-derived neurons, and sophisticated mouse genetics. The lab also utilizes multi-OMICs approaches in collaboration with core facilities for single-cell analytics and metabolomics. Dr. McWilliams' publication record demonstrates consistent productivity with 35 research outputs over the past decade. His recent work shows increasing focus on longitudinal studies of autophagy in brain aging, the genetic basis of autophagy disorders, and metabolic regulation of mitochondrial quality control pathways. His research bridges basic cellular mechanisms with clinical applications in neurodegenerative diseases. Scientific recognition includes four prestigious journal cover images: Journal of Cell Biology (2016) FEBS Journal (2018) Open Biology (2018) Current Opinion in Cell Biology (2017) Dr. McWilliams actively mentors the next generation of scientists through in-depth training in his laboratory and supervision of doctoral students. He has secured significant research funding including a €1.1 million grant from Jane ja Aatos Erkon säätiö (2024-2028), funding from Instrumentariumin tiedesäätiö (2024), and support from Päivikki ja Sakari Sohlbergin säätiö (2023-2024). He also participates in the Research Council of Finland's University Profile project through 2030. The McWilliams Lab maintains strong international collaborations and utilizes advanced core facilities in Helsinki for single-cell analytics and metabolomics. The lab's work has important implications for understanding and treating neurodegenerative conditions through targeting cellular quality control mechanisms.