جست‌وجوی استاد و پژوهشگر

Thomas C. Richمشاهده پروفایل

استاد

• Cell Signaling
• cAMP Signaling
• Biomedical Imaging
• +۵ مورد دیگر

Thomas C. Rich serves as Professor of Pharmacology and Director of the Bioimaging Core Facility at the University of South Alabama's Frederick P. Whiddon College of Medicine, where he leads innovative research in cellular signaling dynamics and advanced imaging technologies. His educational background includes: Baccalaureate with Honors in Engineering from Georgia Institute of Technology Masters in Aerospace Engineering from Georgia Institute of Technology Ph.D. in Biomedical Engineering from Vanderbilt University Dr. Rich's research focuses on cellular signaling specificity , particularly cAMP pathways and phosphodiesterase regulation . His laboratory pioneered single-cell cAMP sensors and excitation-scanning hyperspectral imaging (HSI) techniques enabling 100-fold signal-to-noise improvements over traditional FRET. Key contributions include mapping cAMP gradients in pulmonary endothelial cells and airway smooth muscle, revealing previously undetectable signaling microdomains through collaborations with Dr. Silas Leavesley and Dr. Michael Francis. Analysis of his 14 publications (2015-2024) shows consistent innovation in quantitative imaging and signal transduction , with increasing emphasis on multi-parametric measurement (cAMP, Ca2+, NO, cGMP) and real-time dynamic tracking . His work spans fundamental enzymology to clinical applications, particularly in respiratory physiology and endoscopic technology development. No scientific awards were mentioned in the provided documentation. While specific advisees and grant details are not documented, Dr. Rich's research program demonstrates extensive collaboration through co-authorship patterns and facility leadership. His Bioimaging Core Facility serves as a hub for interdisciplinary projects requiring advanced fluorescence measurement capabilities. Dr. Rich leads the Bioimaging Core Facility in a collaborative research ecosystem centered around hyperspectral imaging development. His team works closely with Dr. Leavesley on optical system engineering and Dr. Francis on dynamic region-of-interest algorithms, creating an integrated approach to overcome limitations in cellular signal measurement within the 'turbulent maelstrom of the cellular environment'.

• Cell Mechanics
• Tissue Engineering
• Corneal Wound Healing
• +۷ مورد دیگر

Dr. W. Matthew Petroll is a Professor in the Department of Ophthalmology and the Graduate Program in Biomedical Engineering at UT Southwestern Medical Center. He serves as Vice Chair of Research in Ophthalmology and previously directed the Biomedical Engineering Graduate Program from 2012 to 2025. His interdisciplinary work bridges engineering and clinical ophthalmology, focusing on corneal cell mechanics and tissue engineering. Dr. Petroll earned his BS in Biomedical Engineering from Duke University (1984) and PhD from the University of Virginia (1989). He joined UT Southwestern in 1991 after postdoctoral training at Georgetown University. His research centers on cell mechanics , corneal wound healing , and extracellular matrix dynamics , using in vivo confocal microscopy and 3D time-lapse imaging to study fibroblast behavior. His lab investigates how biochemical and biophysical cues regulate keratocyte differentiation, migration, and matrix remodeling in response to injury, surgery, and disease. His recent publications (2023–2025) highlight work on UV cross-linking effects , corneal fibrosis , gene expression in Fuchs’ dystrophy , and biomimetic collagen scaffolds . These studies demonstrate a consistent focus on mechanobiology and regenerative strategies for corneal transparency. Dr. Petroll has trained numerous graduate students, medical students, and postdocs through his active research lab. He has held leadership roles in academic programs and research administration, reflecting his institutional impact. His lab, the Petroll Lab , is embedded within the Department of Ophthalmology and collaborates extensively on corneal imaging, biomechanics, and translational research. The lab develops innovative models for assessing 3D cell-matrix interactions in vitro and in vivo.

Hiroshi Nishiyamaمشاهده پروفایل

دانشیار

• Electrophys
• Optogenetics & Chemogenetics
• Optical Imaging
• +۲ مورد دیگر

Hiroshi Nishiyama is an Associate Professor in the Department of Neuroscience at the University of Texas at Austin. His research focuses on synaptic plasticity and circuit reorganization in the mammalian cerebellum, with implications for learning, memory, and brain injury recovery. Education: B.S., Kyoto University (1992–1996) M.S., Kyoto University (1996–1998) Ph.D., Kyoto University & RIKEN Brain Science Institute (1998–2002) Postdoctoral Research, Johns Hopkins University (2002–2008) His work explores how cerebellar circuits are refined during development, reorganized in adulthood through learning, and rewired after injury. Techniques include electrophysiology , optogenetics , and long-term in vivo imaging of synaptic dynamics. Recent publications highlight mechanisms of Purkinje cell ablation , lesion-induced axonal sprouting , and dendritic translocation in synaptic competition. These studies span developmental neuroscience , neurotrauma , and neurodegenerative models . The Nishiyama Lab investigates cerebellar circuits as critical nodes in brain-wide functional architecture, bridging motor control and broader neurological disorders.

• Light Sheet Microscopy
• Biomedical Imaging
• Developmental Biology
• +۴ مورد دیگر

Jan Huisken is a Humboldt Professor for Multiscale Biology at the Georg-August-Universität Göttingen, affiliated with the Johann Friedrich Blumenbach Institute of Zoology and Anthropology. His research focuses on advanced light sheet microscopy techniques for biomedical and developmental biology applications. Role: Humboldt Professor University: Georg-August-Universität Göttingen Department: Johann Friedrich Blumenbach Institute of Zoology and Anthropology Research interests include light sheet microscopy , biomedical imaging , and developmental biology with a strong emphasis on zebrafish models. He develops tools for tissue clearing , image processing , and 3D microscopy . The 15 most recent publications analyze innovations in light sheet microscopy, tissue clearing protocols, and computational methods for image restoration. These works span fields such as optical imaging , developmental cardiology , computational biology , and biomedical instrumentation . Huisken contributes to open-source microscopy systems like 'Flamingo' and 'BigFUSE,' aiming to democratize access to advanced imaging technologies. His work integrates engineering, computer science, and biology to solve complex imaging challenges.

Jun Allardمشاهده پروفایل

استاد

• Mathematical Biology
• Computational Biology
• Cell Mechanics
• +۴ مورد دیگر

Jun Allard is a Professor at the University of California, Irvine, with joint appointments in the Department of Mathematics and Department of Physics and Astronomy. He is affiliated with the Center for Complex Biological Systems and the NSF-Simons Center for Multiscale Cell Fate Research. Education includes: Ph.D. Applied Mathematics, University of British Columbia (2011) M.Sc. Physics, Dalhousie University (2007) B.Sc. Mathematical Physics, Queen's University (2005) His research specializes in mathematical and computational modeling of cellular and biomolecular mechanics. Key interests include how cells utilize force, space, and time to solve problems, with applications in immune cell signaling, cytoskeletal dynamics, and intracellular transport. His work combines theoretical models with experimental collaborations to uncover fundamental biological mechanisms. Recent publications (2021-2025) predominantly focus on computational approaches to cellular processes, including molecular transport mechanisms, immune receptor dynamics, and cytoskeletal organization. These studies employ advanced stochastic modeling, biophysical simulations, and quantitative experimental methods to reveal principles governing cellular behavior. Scientific awards include: UCI Chancellor's Award for Distinguished Fostering of Undergraduate Research (2015) Emerging Diversity Scholar, National Center for Institutional Diversity (2016) Honorable Mention, NSF Graduate Research Fellowship (2012) He has advised over 12 doctoral students and leads the Allard Lab, which develops computational models for cell mechanics. Major grants include NSF awards for research on molecular-tether reactions (DMS-2052668), nanoparticle adhesion (CBET-1929565), and multiscale cell fate (DMS-1763272). The lab collaborates internationally with experimental groups and participates in interdisciplinary initiatives including the Chemical and Materials Physics program.

Salavat Aglyamovمشاهده پروفایل

استاد پژوهشی

• Elastography
• Biomechanics
• Biomedical Imaging
• +۷ مورد دیگر

Dr. Salavat Aglyamov is a Research Professor in the Department of Mechanical and Aerospace Engineering at the University of Houston. His work focuses on biomechanical imaging and elastography techniques such as optical coherence elastography (OCE), Brillouin microscopy, and ultrasound. He leads the Biomedical Optics Laboratory and teaches courses in biomedical engineering. Research interests include corneal biomechanics, tissue stiffness analysis in diseases like glaucoma and keratoconus, and developmental biology applications in embryos and zebrafish models. Key innovations involve multimodal imaging systems combining OCT with other modalities for non-invasive tissue characterization. Recent studies address age-related lens changes, drug delivery monitoring, and the biomechanics of neural tube defects in mouse embryos. Education: Ph.D., Institute of Theoretical and Experimental Biophysics, Pushchino, Russia His research applies machine learning (CNNs) to improve strain estimation in OCE and explores clinical applications like glaucoma detection and corneal crosslinking treatment efficacy. He collaborates on projects involving systemic sclerosis assessment via OCT/OCE/OCTA and has developed novel methods for safe acoustic radiation force-based measurements on ocular tissues. His lab’s work spans from fundamental material science (e.g., Brillouin frequency shifts under environmental conditions) to translational medicine (e.g., drug delivery tracking). Publications emphasize high-resolution 3D elasticity mapping of embryos, alcohol’s impact on embryonic development, and nanobomb OCE for glioblastoma studies. His work bridges engineering and medicine through advanced optical techniques for understanding tissue mechanics in health and disease.

Mitchell F. Balishمشاهده پروفایل

استاد

• Microbiology
• Bacterial Cell Biology
• Cytoskeleton
• +۷ مورد دیگر

Mitchell F. Balish is a Professor and Assistant Chair in the Department of Microbiology at Miami University, affiliated with the Cell, Molecular and Structural Biology Graduate Program. His research focuses on the molecular and structural biology of mycoplasmas, particularly their cytoskeletal organization, attachment organelles, and mechanisms of virulence. Dr. Balish earned his Ph.D. in Biochemistry and Molecular Biology from Emory University in 1998. His research seeks to understand the complex cellular organization of mycoplasmas—bacteria lacking cell walls with minimal genomes—especially how their unique cytoskeletons contribute to pathogenesis. He investigates species such as Mycoplasma pneumoniae , M. penetrans , and M. iowae , which are linked to respiratory, urogenital, and poultry diseases. His laboratory employs advanced techniques including molecular biology, protein biochemistry, genomics, time-lapse imaging, and fluorescence and electron microscopy. Research themes span bacterial cytoskeletons, gliding motility, biofilm formation, cytadherence, and antibiotic resistance. Recent publications highlight biofilm persistence, attachment organelle structure, and oxidative stress defense mechanisms. Dr. Balish has mentored numerous graduate and undergraduate students, many of whom are co-authors on his publications. He has not received any explicitly mentioned scientific awards. His lab continues to explore fundamental questions in bacterial cell biology with implications for developing narrow-spectrum antimicrobial agents.

Lee Rubinمشاهده پروفایل

استاد

• Neurodegenerative Diseases
• Aging Biology
• Stem Cell Biology
• +۵ مورد دیگر

Lee Rubin is Professor of Stem Cell and Regenerative Biology at Harvard University and Co-director of the Harvard Stem Cell Institute Nervous System Disease Program. His research focuses on molecular mediators of neurodegenerative diseases, aiming to identify preclinical therapeutic candidates through translational approaches. Education: Ph.D. in Neuroscience (The Rockefeller University), Postdoctoral Fellowships in Pharmacology (Harvard Medical School) and Neurobiology (Stanford University School of Medicine). Former Industry Role: Chief Scientific Officer at Curis, Inc., where his team pioneered hedgehog signaling pathway regulators leading to Erivedge (metastatic basal cell carcinoma treatment). Research Directions: The Rubin Lab combines patient iPSC models, genetic mouse studies, and high-throughput screening to investigate: Aging brain mechanisms and GDF11's role in neurogenesis Neuromuscular disorders like Spinal Muscular Atrophy (SMA) Small molecule discovery for stem cell regulation Neurovascular interactions in Alzheimer's disease Recent Publications demonstrate expertise in single-cell transcriptomics, circulatory factor effects on CNS aging, and precision medicine approaches for Parkinson's disease. Collaborations span Harvard, Broad Institute, and translational medicine networks. Lab Composition: Includes 15+ active researchers, with dedicated teams for: GDF11 neurovascular effects Motor neuron degeneration modeling High-content screening platforms Brain aging multiomics

• Artificial Intelligence
• Deep Learning
• Machine Learning
• +۱۱ مورد دیگر

Fatima Boukari is an Associate Professor in Computer Science within the Division of Physics, Engineering, Mathematics and Computer Sciences at Delaware State University. Her research bridges artificial intelligence, deep learning, and mathematical modeling to develop robust solutions for biomedical engineering, cell biology, and agricultural technology challenges. Education: B.Sc. in Computer Science Engineering from University of Annaba, Algeria Dual M.Sc. degrees in Computer Systems Architectures and Parallel Computing from Algeria-Glasgow Ph.D. in Mathematics & Physics from Delaware State University Dr. Boukari's research centers on foundational Deep Learning architectures and mathematical modeling applied to biomedical diagnostics and cell dynamics analysis. Her work in reinforcement learning and transfer learning enhances decision-making for autonomous systems, while her cognitive modeling research decodes human perception using EEG data. She pioneers multi-modal distributed learning systems that maintain privacy across heterogeneous sensor networks, addressing critical gaps in military ISR applications. Her recent publications reveal a strong trajectory toward spectral data analysis for medical diagnostics and AI-driven cognitive modeling , with increasing emphasis on trustworthy AI solutions for healthcare and environmental sustainability. The consistent focus on cell segmentation/tracking algorithms demonstrates her commitment to advancing biomedical image analysis. Scientific Awards: No scientific awards, prizes, or fellowships listed in available information Dr. Boukari has mentored over 40 undergraduate and 2 graduate students from underrepresented STEM backgrounds. Her active research portfolio includes: NSF CISE grant for biomolecular detection using physics-informed machine learning Air Force RITA/UARC project on neuroscience computational modeling Air Force project building robust multi-modal distributed learning systems DE-CTR ACCEL project for COVID-19 respiratory disease diagnosis NSF grant for Delaware and Mid-Atlantic Data Science Corps Research scientist role in AI-CLIMATE National AI Research Institute She leads the Applied Interdisciplinary Data Science (AIDA) Laboratory and serves as Project Lead for the CAST E-IoT Center's four agricultural research thrusts. As Team Lead of the 1890 Working Group on Artificial Intelligence, she drives initiatives addressing climate change resilience and food security through responsible AI development.

Bree Aldridgeمشاهده پروفایل

استاد

• Tuberculosis
• Mycobacterium tuberculosis
• Drug Tolerance
• +۵ مورد دیگر

Bree Aldridge is a Professor at Tufts University with joint appointments in the School of Medicine (Molecular Biology and Microbiology) and School of Engineering (Biomedical Engineering) . Her work bridges cell biology, computational modeling , and antibiotic discovery to combat tuberculosis and drug-resistant pathogens. Her research focuses on Characterizing single-cell determinants of mycobacterial drug tolerance Understanding growth heterogeneity control in bacteria Engineering optimized antibiotic combination therapies using quantitative measurements and systems approaches. Her recent publications highlight trends in multi-drug interaction analysis , single-cell imaging of tuberculosis , and AI-driven antibiotic discovery . She has received multiple teaching honors, including three Best Course nominations from Tufts University. Grants from the Bill & Melinda Gates Foundation and National Institutes of Health support her work on tuberculosis drug regimen optimization, myeloid cell suppression in granulomas, and stress response modeling. She actively contributes to conferences, symposia, and university committees in systems pharmacology and biosafety.

Anand Subramaniamمشاهده پروفایل

دانشیار

• Biomolecular Science and Engineering
• Nanotechnology
• Biomembrane Engineering
• +۳ مورد دیگر

Anand Subramaniam is an Associate Professor and Chair of the Department of Bioengineering at the University of California, Merced. His research focuses on understanding the physicochemical mechanisms governing biomembrane assembly and function, using tools from soft matter physics, chemistry, and molecular biology. He leads the Subramaniam Lab, which develops biomimetic materials and semi-synthetic cells for applications in therapeutics and diagnostics. Education: PhD in Applied Physics (Harvard University, 2011), S.M. in Applied Physics (Harvard University, 2011), A.B. in Biology (Harvard University, 2005, Cum Laude). Awards include the UC Merced Academic Senate Award for Distinguished Early Career Research (2018–2019) and the NSF CAREER Award (2019). He co-founded the NASA Merced Nanomaterials Center for Energy and Sensing (MACES) and is a senior investigator at the Center for Cellular & Biomolecular Machines (CCBM). Research interests span biomimetic materials, vesicle engineering, and bottom-up synthetic biology. His lab pioneered the PAPYRUS method for high-yield giant vesicle assembly using cellulose substrates. Key projects include developing cost-effective vesicle-based therapeutics and studying lipid-glycan interactions in membrane dynamics. Advising: Mentors over 20 graduate and undergraduate students, including PhD candidates in Bioengineering, Chemistry, and Quantitative & Systems Biology. Alumni hold roles at institutions like Harvard University, Genentech, and Beckman Coulter. Labs/Teams: Principal Investigator at the Subramaniam Lab; affiliated with MACES, CCBM, and the UC Merced Department of Bioengineering. Collaborations span interdisciplinary groups in materials science, biophysics, and synthetic biology.

Jennifer Fungمشاهده پروفایل

دانشیار

• Genetics
• Cell Biology
• Meiosis
• +۳ مورد دیگر

Jennifer Fung is an Associate Professor at the University of California, San Francisco (UCSF), affiliated with the Center for Reproductive Sciences. Her academic work focuses on understanding the mechanisms of chromosome segregation during meiosis, with particular emphasis on crossover regulation. Dr. Fung received her B.S. in Biophysics from the University of California, Berkeley in 1987, followed by a PhD in Biophysics from UCSF in 1996. She completed postdoctoral training in Genetics at Yale University in 2003 and a fellowship in Genomics/Cell Biology at UCSF in 2008. Her research interests span multiple areas of genetics and cell biology, with a primary focus on meiosis, chromosome dynamics, and genetic recombination. Using advanced techniques including time-lapse microscopy, structural illumination microscopy, microarray analysis, and biochemical approaches, her lab investigates how crossover control affects chromosome segregation during meiosis. Her work has important implications for understanding genetic disorders that arise from errors in chromosome segregation. Dr. Fung's publications demonstrate consistent contributions to the field of meiotic recombination, with research spanning from basic chromosome pairing mechanisms to the regulation of crossover interference. Her work bridges molecular genetics with cellular dynamics, providing insights into fundamental biological processes. Among her notable achievements are the Mentor Fellowship from UCSF (1992), the International Congress of Electron Microscopy Student Award (1994), the Damon Runyon-Walter Winchell Cancer Foundation Fellowship (1996), and the UCSF Fellow Program Fellowship from The Sandler Foundation (2003). Through her research and mentorship, Dr. Fung has made significant contributions to our understanding of meiotic processes and chromosome dynamics, with implications for reproductive health and genetic stability.

Hawa Racine Thiamمشاهده پروفایل

استادیار

• Biophysics
• Cell Biology
• Immunology
• +۵ مورد دیگر

Hawa Racine Thiam is an Assistant Professor of Bioengineering and Microbiology & Immunology at Stanford University , where she holds appointments in the Bio-X, Maternal & Child Health Research Institute (MCHRI), and Sarafan ChEM-H. Her research integrates microscopy , microfabrication , and quantitative cell biology to study the cellular biophysics of immune cells , particularly NETosis - a neutrophil-mediated pathogen-trapping mechanism with implications in both infection and sterile inflammation. Ph.D. in Biophysics from Institut Curie/Paris Descartes University (2014) Postdoctoral training in Quantitative Cell Biology at National Institutes of Health (2022) Co-inventor of microfabricated devices for cellular mechanics analysis Her lab's publications reveal trends in nuclear deformation mechanics , cytoskeletal dynamics , and RNA-protein complexes in autoimmunity . Key techniques include high-resolution time-lapse microscopy , mechanical modeling , and microenvironment engineering . Chan Zuckerberg Biohub Investigator (2022-2027) Esther Ehrman Lazard Faculty Scholar (2022-2025) ASCB Porter Prize Honorable Mention (2020) NIH Fellow Award (2019) As a mentor, she serves as Doctoral Dissertation Advisor and Postdoctoral Faculty Sponsor , guiding students in Bioengineering , Biophysics , and Immunology Ph.D. programs. Her work at Stanford's HR Thiam Lab aims to engineer innate immune cells for enhanced host defense while mitigating pathological inflammation through mechanobiological insights.

Albrecht Schwabمشاهده پروفایل

استاد

• Physiology
• Biochemistry
• Cancer Biology
• +۷ مورد دیگر

Prof. Dr. Albrecht Schwab is a faculty member at the Institute of Physiology II , affiliated with the Medical Faculty of Münster University . He leads the Cell Migration Group , focusing on the role of ion channels and ion transporters in tumor and immune cell migration. Key research areas include calcium signaling , pH regulation , and mechanosensitivity in cancer progression and neutrophil function. Department: Institute of Physiology II University: University of Münster Research Networks: Cells in Motion, pHioniC (2018-2023), IonTraC (2011-2015) His work investigates how ion transport proteins like KCa3.1 , TRP channels , and the Na+/H+ exchanger (NHE1) drive cancer metastasis and immune cell chemotaxis. Projects include mechanosignaling in pancreatic stellate cells, TRP channel roles in neutrophil activation, and epigenetic dysregulation of ion channels in lung cancer. Techniques employed include time-lapse videomicroscopy , live-cell fluorescence , and atomic force microscopy . Articles highlight trends in ion channel imaging (PET/fluorescent probes), mechanotransduction in fibrosis, and calcium/pH signaling in melanoma and pancreatic cancer. The lab collaborates with technical staff (Ilka Neumann, Sarah Sargin, Sandra Schimmelpfennig) and participates in European research consortia.

Kyle E Millerمشاهده پروفایل

دانشیار

• Neuroscience
• Cell Biology
• Biophysics
• +۴ مورد دیگر

Kyle E Miller serves as an Associate Professor at Michigan State University with cross-program appointments in the Integrative Biology Faculty, Neuroscience Program, and Genetics & Genome Sciences Program. His laboratory operates from room 337 of the Natural Science Building, where he leads research on fundamental mechanisms of neuronal development. Dr. Miller's research program centers on elucidating the biophysical and molecular mechanisms underlying axon growth. His laboratory employs an integrative methodology combining time-lapse microscopy in living Drosophila embryos and cultured neurons, mathematical modeling of cytoskeletal dynamics, targeted gene disruption, and biophysical force measurements. This multidisciplinary approach specifically investigates organelle biogenesis, transport kinetics, and cytoskeletal element degradation during neurite outgrowth, with translational aims toward improving treatments for traumatic brain injury, spinal cord injury, stroke, and chronic neurodegenerative conditions. Analysis of his 15 most recent publications (2017-2025) reveals three dominant research trajectories: (1) evolutionary hypotheses connecting cytokinesis to neuronal development, (2) active fluid modeling of cytoskeletal mechanics in axonal elongation, and (3) molecular motor regulation of organelle transport (particularly mitochondria and lysosomes). These works consistently bridge neuroscience, cell biology, and biophysics through innovative combinations of in vivo imaging and computational approaches. No scientific awards are documented in the available materials. Dr. Miller maintains an active research laboratory conducting both basic and translational neuroscience investigations, though specific grant funding details and student mentorship records are not provided in the source documentation. The Miller Lab utilizes Drosophila embryonic models and primary neuronal cultures to dissect the mechanical and molecular drivers of axonal elongation, with particular emphasis on microtubule dynamics, molecular motor function, and the evolutionary origins of neuronal structures.