Despina Kontos, PhD is the Herbert and Florence Irving Professor of Radiological Sciences at Columbia University Irving Medical Center (CUIMC), with appointments in the Department of Radiology and the Herbert Irving Comprehensive Cancer Center. She serves as the Chief Research Information Officer for CUIMC, Vice Chair of Artificial Intelligence and Data Science Research in the Department of Radiology, and Director of Biomarker Imaging at NewYork-Presbyterian Hospital. Additionally, she holds appointments in the Departments of Biomedical Informatics and Biomedical Engineering. Dr. Kontos received her educational training from prestigious institutions: BS in Engineering from the University of Patras, Greece MSc and PhD in Computer and Information Sciences from Temple University Postdoctoral training in Radiology at the University of Pennsylvania Certificates in Biostatistics and Epidemiology from UPenn, Cancer Biology from Harvard, and AI for Decision Making from Wharton As a computer scientist with expertise in artificial intelligence and machine learning, Dr. Kontos focuses on developing computational methodologies to leverage imaging as quantitative biomarkers for personalized disease prediction, particularly in cancer. Her research program investigates how imaging data can be mined to extract sophisticated phenotypic signatures with diagnostic, prognostic, and predictive value. While her primary focus has been on breast cancer, her lab also pursues related research in lung cancers, evaluating the integration of CT radiomic features with liquid biopsy data to characterize tumor heterogeneity. Dr. Kontos founded and directs Columbia University's Center for Innovation in Imaging Biomarkers and Integrated Diagnostics (CIMBID), a multidisciplinary center dedicated to developing and integrating quantitative imaging and non-imaging biomarkers for personalized disease prediction. Through CIMBID, she has built a vibrant scientific ecosystem that brings together expertise across Columbia's campuses, linking basic science, engineering, clinical medicine, public health, and health services research. Analysis of Dr. Kontos's publication record reveals a strong focus on applying AI and machine learning to biomedical imaging, particularly for cancer risk prediction and personalized treatment. Her work demonstrates a progression from foundational methodological development to clinical translation, with increasing emphasis on multi-modal biomarker integration. Recent publications show expansion into new disease areas including Alzheimer's disease prediction, while maintaining her strong focus on breast and lung cancer applications. Dr. Kontos has received significant recognition for her contributions to the field: Academy for Radiology and Biomedical Imaging Research Distinguished Investigator Award (2020) Eastern Cooperative Oncology Group - American College of Radiology Imaging Network ECOG-ACRIN Young Investigator Award of Distinction for Translational Research (2014) Dr. Kontos has been highly successful in securing research funding, with numerous grants from federal agencies including the National Institutes of Health (NIH) and the Department of Defense (DOD), as well as private foundations such as the American Cancer Society (ACS) and the Radiological Society of North America (RSNA). Her leadership extends to mentoring students and postdoctoral researchers through her roles at CIMBID and the Department of Radiology. As the founding director of CIMBID, Dr. Kontos leads a multidisciplinary team that includes the Computational Imaging Biomarker Group (CBIG), the Laboratory of AI and Biomedical Science (LABS), and several other affiliated research labs. The center leverages Columbia's institutional strengths in engineering, data science, and clinical medicine to advance personalized healthcare through AI and imaging technologies.








