جست‌وجوی استاد و پژوهشگر

Keith Alexander Sharkeyمشاهده پروفایل

استاد

• Enteric nervous system
• Gut-brain axis
• Endocannabinoid system
• +۳ مورد دیگر

Dr. Keith Alexander Sharkey is a Professor in the Department of Physiology and Pharmacology at the Cumming School of Medicine, University of Calgary. He is also a Full Member of both the Hotchkiss Brain Institute and The Calvin, Phoebe and Joan Snyder Institute for Chronic Diseases. Dr. Sharkey has been at the University of Calgary since his appointment as Assistant Professor in 1990, dedicating his career to understanding the neural control of the gastrointestinal tract. From 2005-2021, he held the Crohn's and Colitis Canada Chair in Inflammatory Bowel Disease Research, demonstrating his longstanding commitment to advancing knowledge in gastrointestinal sciences. Dr. Sharkey's educational journey began with a BSc (Hons) in Nutrition from the University of London in 1981, followed by a PhD in Physiology from the University of Liverpool in 1985. After completing postdoctoral training in Hungary, the UK, and Canada, he joined the University of Calgary faculty in 1990, where he has remained throughout his distinguished academic career. Dr. Sharkey's research program centers on understanding the physiology and pathophysiology of the neural control of the gastrointestinal tract and brain-gut interactions in health and disease. His laboratory investigates two main areas: the role of the endocannabinoid system in regulating GI motility and intestinal barrier function, and the physiology of the enteric nervous system in controlling motility and barrier function. His work employs state-of-the-art approaches including live cell imaging and molecular genetics. Recent publications show his expanding interest in connections between gut function and neurodegenerative conditions like ALS, with multiple 2024-2025 papers examining sexual dimorphism in disease processes and gut-brain axis mechanisms. Fellow, Royal Society of Canada (2024) Cumming School of Medicine's van de Sande Distinguished Achievement Award for Mentorship (2021) Distinguished Research Award, American Physiological Society (2021) Finkelstein Award for Excellence, Crohn's and Colitis Canada (2016) Fellow, Canadian Academy of Health Sciences (2015) Fellow, Canadian Association of Gastroenterology (2015) Killam Annual Professor Award, University of Calgary (2013) Dr. Sharkey has mentored numerous students throughout his career, as evidenced by his 2021 Mentorship Award. His research is supported by significant funding, including a CIHR Foundation grant exploring how enteric nerves and glia maintain intestinal homeostasis. He has also participated in university strategic initiatives focused on Brain and Mental Health (2015-2021) and Infections, Inflammations and Chronic Diseases (2015-2021), demonstrating his interdisciplinary approach. The Sharkey Lab provides a safe, inclusive, and diverse research environment that encourages open scientific exchange from diverse viewpoints. His laboratory is actively engaged in multiple collaborative projects, including investigations with UBC Okanagan on diet and probiotics targeting the gut-brain metabolic interactome, and with University of Calgary colleagues studying gut microbiota's role in ALS. Dr. Sharkey continues to advance our understanding of neural mechanisms controlling gastrointestinal function with upcoming courses scheduled for Fall 2024 and Winter 2025.

Sriram Subramaniamمشاهده پروفایل

استاد

• cryo-electron microscopy
• structural biology
• drug-design
• +۴ مورد دیگر

Sriram Subramaniam is a Professor in the Department of Biochemistry and Molecular Biology at the University of British Columbia (UBC) and holds the Gobind Khorana Canada Excellence Research Chair in Precision Cancer Drug Design. His research leverages cryo-electron microscopy (cryo-EM) to advance structural biology and drug design, focusing on protein dynamics and therapeutic target identification. Education: PhD in Physical Chemistry (1987) from Stanford University; MSc in Chemistry (1981) from Indian Institute of Technology, Kanpur. Subramaniam's interdisciplinary work combines cryo-EM with computational tools and molecular biology to study protein structures at atomic resolution. His lab has pioneered cryo-EM applications in precision medicine, including mapping small molecule drugs on patient-specific cancer mutants. Recent publications (2024-2022) highlight his contributions to understanding SARS-CoV-2 immune evasion, structural mechanisms of ATPases, and AI integration in structural biology. His research spans viral entry mechanisms, CRISPR systems, and neurodegenerative disease pathways. Scientific Awards: Gobind Khorana Canada Excellence Research Chair NIH Director’s Award for Scientific Excellence Fellow of the Biophysical Society Breakthrough Prize nomination Based at the Djavad Mowafaghian Center for Brain Health, Subramaniam leads the Program in Cryo-EM Guided Drug Design, contributing to over 177 peer-reviewed publications with a career h-index of 58 and citations exceeding 12,340.

Sachdev Sidhuمشاهده پروفایل

استاد پژوهشی

• Synthetic Antibodies
• Protein Engineering
• Biotechnology
• +۵ مورد دیگر

Sachdev Sidhu is a Research Professor and Entrepreneur in Residence at the University of Waterloo. His research focuses on synthetic antibodies, protein engineering, and biotechnological applications. He leads efforts in developing novel therapeutic antibodies, engineered protein systems, and molecular tools for biomedical research. His work spans cancer therapy, viral infection countermeasures, and regenerative medicine. Sidhu is also involved in translational research, bridging academic discoveries with commercial applications through entrepreneurial ventures. Key research interests include synthetic antibody libraries, CAR T-cell engineering, ubiquitin-based therapeutics, and phage display technologies. He has contributed to advancements in targeted therapies for glioblastoma, leukemia, and ocular diseases. His team develops innovative methods for protein design, such as engineered ubiquitin variants and modular antibody architectures. Publications highlight breakthroughs in antibody-based treatments, including synNotch CAR T cells for glioblastoma and neutralizing antibodies against SARS-CoV-2. His work integrates structural biology, molecular biology, and computational approaches to address complex biomedical challenges. Sidhu collaborates with industry partners to advance technologies into clinical and commercial settings.

Jacques Archambaultمشاهده پروفایل

استاد

• Human Papillomavirus (HPV)
• Polyomavirus
• Viral DNA Replication
• +۴ مورد دیگر

Dr. Jacques Archambault is a Professor in the Department of Microbiology and Immunology at McGill University , and an associate member of the Division of Experimental Medicine since 2016. His research focuses on the molecular biology and pathogenesis of human papillomaviruses (HPVs) and polyomaviruses (HPyVs), with an emphasis on their replication mechanisms as episomes in host cells. The Archambault laboratory employs functional genomics, proteomics, and chemical biology approaches to identify cellular pathways exploited by these viruses and develop high-throughput assays for screening small molecule inhibitors of viral replication. Analysis of his recent publications reveals a strong focus on HPV and HPyV replication machinery, including studies on the E1 helicase, UAF1-USP1 interactions, and structural characterization of viral proteins involved in DNA replication. His work bridges virology, oncology, and drug discovery, particularly targeting oncogenic HPV types implicated in anogenital and oropharyngeal cancers, as well as HPyVs like BKPyV and JCPyV that cause pathologies in immunosuppressed patients. Current efforts in the lab aim to elucidate the molecular mechanisms by which HPVs and HPyVs replicate their genomes and to develop antiviral therapies targeting these processes. Techniques such as fluorescence anisotropy, NMR spectroscopy, and crystallography are frequently employed to study protein-DNA and protein-protein interactions critical to viral replication.

Hong Hanمشاهده پروفایل

استادیار

• Cancer Biology
• Gene Regulation
• RNA Splicing
• +۵ مورد دیگر

Hong Han is an Assistant Professor in the Department of Biochemistry & Biomedical Sciences within McMaster University's Faculty of Health Sciences and a member of the Centre for Discovery in Cancer Research (CDCR). She holds a Canada Research Chair and leads the Han Lab, which focuses on cancer biology, RNA regulation, and innovative high-throughput technologies for therapeutic discovery. Dr. Han earned her Ph.D. from the University of Toronto (2010-2016) and has established herself as a leading researcher in glioblastoma and alternative splicing regulation. Her interdisciplinary research integrates cancer biology, RNA science, and multilayer gene regulation to uncover mechanisms underlying cancer progression and treatment resistance. Her laboratory pioneers integrated technological platforms for large-scale genetic/drug screening and ultra-high-throughput single-cell profiling. The research focuses on three main areas: alternative splicing regulation in cancer (particularly glioblastoma and prostate cancer), multilayer mechanisms of glioblastoma heterogeneity and microenvironment evolution, and multiplexed screening approaches for therapeutic discovery in treatment-resistant cancers. Analysis of Dr. Han's recent publications reveals a strong emphasis on single-cell technologies to characterize glioblastoma heterogeneity, minimal residual disease states, and tumor-immune interactions. Her work increasingly bridges basic RNA biology with translational applications, particularly in developing novel therapeutic strategies targeting splicing networks and immune evasion mechanisms. Canada Research Chair Dr. Han teaches Advanced Techniques in the Biomedical Sciences (BIOCHEM 734). Her research program is supported by multiple funding sources, as evidenced by her extensive publication record in high-impact journals including Nature, Cell, Molecular Cell, and Nature Communications. She employs a comprehensive approach combining in vitro, in vivo, and patient cohort studies with cutting-edge genomic technologies. The Han Lab has developed innovative multiplexed screening platforms that enable simultaneous interrogation of thousands of conditions, ranging from CAR-T cells to small molecule therapeutics. This approach accelerates the discovery of novel cancer targets and therapeutic strategies for treatment-resistant cancers.

Gabriela V. Cohen Freueمشاهده پروفایل

دانشیار

• Statistical Methodology
• High-Dimensional Data Analysis
• Robust Statistics
• +۶ مورد دیگر

Gabriela V. Cohen Freue is an Associate Professor in the Department of Statistics at the University of British Columbia (UBC), Vancouver Campus, and holds a Canada Research Chair (CRC Tier 2). She leads an interdisciplinary research program focusing on developing robust statistical methodologies for analyzing high-dimensional data in genomics and proteomics, with applications in medical sciences. Her work addresses challenges such as outliers, collinearity, and measurement errors, with applications in biomarker discovery for diseases like multiple sclerosis, cardiovascular disorders, and asthma. Her academic journey includes collaborations across disciplines, including with the BC Cancer Agency, PROOF Centre of Excellence, and iCAPTURE. She has pioneered methods like the Penalized Elastic Net S-Estimator (PENSE) and contributed to proteomic data analysis tools such as the Protein Group Code Algorithm (PGCA). She also co-developed the MDQC quality control method for microarrays. Research interests include robust regression, biomarker development, and statistical methods for big data. Her team includes postdocs, PhD, and MSc students, with a focus on training in both statistical rigor and interdisciplinary collaboration. Notable grants include a CANSSI Collaborative Research Team Project (CRT) award for robust causal inference and prediction modeling. Teaching responsibilities span statistical consulting, high-dimensional biological data analysis, and generalized linear models. She emphasizes active learning and real-world problem-solving in her courses. Her lab’s work is supported by grants from the Data Science Institute (DSI) and collaborations with institutions like the PROOF Centre. Alumni of her group hold positions in academia (e.g., George Mason University) and industry (e.g., Merck, BC Cancer Research Centre).

• Respiratory Medicine
• Asthma Pathophysiology
• Eosinophilic Lung Disorders
• +۳ مورد دیگر

Parameswaran Krishna Nair is a Professor of Medicine and the Frederick E. Hargreave Teva Innovation Chair in Airway Diseases at McMaster University, with a clinical role as Staff Respirologist at the Firestone Institute for Respiratory Health, St. Joseph’s Healthcare Hamilton. His work focuses on complex obstructive airway diseases, severe asthma, and eosinophilic lung disorders, integrating immunology, hematology, and imaging specialists in multidisciplinary care. He leads an advanced airway diseases fellowship training program. University: McMaster University Clinical Affiliation: Firestone Institute for Respiratory Health, St. Joseph’s Healthcare Hamilton His research explores airway autoimmunity, biologics for inflammatory disorders, and pulmonary imaging techniques like hyperpolarized ¹²⁹Xe MRI. Key studies include mechanisms of eosinophilic asthma, corticosteroid dependence, and post-acute sequelae of COVID-19 with rheumatological implications. Recent publications analyze biologic therapies (benralizumab, mepolizumab), ventilation heterogeneity in asthma, and sputum immunoglobulins as biomarkers. Awards include the Frederick E. Hargreave Teva Innovation Chair in Airway Diseases. Scientific Awards: Frederick E. Hargreave Teva Innovation Chair He contributes to clinical guidelines, therapeutic trials, and autoantibody research in severe respiratory diseases.

Zakia Djaoudمشاهده پروفایل

استادیار

• Human Innate Immunity
• Immunogenetics
• Herpesvirus Immunology
• +۸ مورد دیگر

Dr. Zakia Djaoud is an Assistant Professor at the Department of Biochemistry, Microbiology and Immunology (University of Ottawa) and a Scientist at the CHEO Research Institute . Her research focuses on human innate lymphocytes, particularly γδ T cells and NK cells, and their roles in viral infections (e.g., herpesviruses), cancer, and transplantation. She employs advanced techniques like functional immunology, T-cell receptor repertoire analysis, immunogenetics, flow cytometry, mass cytometry, and high-throughput gene sequencing. Education : DVM (Higher National Veterinary School of Algiers), MSc (Paris Descartes/Paris-Est Créteil), PhD (University of Nantes, Human Immunology) Postdoctoral Training : Stanford University, laboratory of Dr. Peter Parham Her recent publications explore HLA-KIR-TCR interactions, viral immune evasion, and lymphocyte functional education. She has contributed to understanding Epstein-Barr virus and CMV immunity, with a focus on receptor polymorphisms and immune cell dynamics. Dr. Djaoud's lab investigates how immunogenetics and herpesvirus infections shape innate lymphocyte repertoires and functional responses.

Xi-Long Zhengمشاهده پروفایل

استاد

• Vascular Smooth Muscle Biology
• Atherosclerosis
• Vascular Disease Mechanisms
• +۴ مورد دیگر

Xi-Long Zheng is a tenured Professor in the Department of Biochemistry and Molecular Biology and Department of Physiology and Pharmacology at the Cumming School of Medicine, University of Calgary. He holds additional appointments as a Member of the Libin Cardiovascular Institute and Associate Member of both the Snyder Institute for Chronic Diseases and Arnie Charbonneau Cancer Institute. His research focuses on vascular smooth muscle biology and its role in cardiovascular diseases. Doctor of Medicine, Hunan Medical University (1986) M.S. in Pharmacology, Hunan Medical University (1989) Doctor of Philosophy in Pharmacology, University of Calgary (1997) Dr. Zheng's research centers on vascular smooth muscle cell differentiation, proliferation, and phenotypic switching in vascular diseases. His laboratory investigates mechanisms of vascular smooth muscle dedifferentiation in atherosclerosis, abdominal aortic aneurysms, and vascular stiffness. Current work explores ferroptosis, epigenetic regulation (particularly BRD4), and PCSK9 functions in vascular pathologies. His studies integrate molecular, cellular, and in vivo approaches to identify novel therapeutic targets for cardiovascular diseases. Analysis of his recent publications reveals strong emphasis on cell death mechanisms (ferroptosis, cuproptosis), epigenetic regulation, lipid metabolism, and immune-vascular interactions in atherosclerosis. His work demonstrates increasing focus on translational applications targeting vascular smooth muscle phenotypic switching and plaque stability. Alberta Innovates ‒ Health Solutions Senior Scholar Award (2008-2015) Heart & Stroke Foundation New Investigator Award (2001-2006) CIHR/Hypertension Society Scholarship Award (2001-2004) Heart & Stroke Foundation Fellowship Award (1999-2001) AHFMR Independent Investigator Award (2008) Dr. Zheng serves on grant panels for Canadian Institutes of Health Research and Heart and Stroke Foundation of Canada. He is an editorial board member for Biochemical Journal and other scholarly publications. His laboratory receives funding from CIHR and NSERC for projects including smooth muscle PCSK9 in abdominal aortic aneurysm pathogenesis, smooth muscle autophagy in vascular aging, and epigenetic regulation of smooth muscle plasticity. The Zheng Lab investigates vascular smooth muscle functions across multiple organ systems including blood vessels, gastrointestinal tract, bladder, and uterus. His research has established critical mechanisms in vascular smooth muscle differentiation and cell cycle regulation, contributing over 100 peer-reviewed publications in high-impact journals including PNAS, ATVB, Diabetologia, JBC, and Hypertension.

• Biosensors
• Point-of-care diagnostics
• CRISPR technology
• +۱۰ مورد دیگر

Hongquan Zhang serves as an Associate Professor in the Department of Laboratory Medicine & Pathology at the Faculty of Medicine & Dentistry, University of Alberta. His research program develops cutting-edge bioanalytical tools for ultrasensitive and point-of-care detection of biological targets, with a particular focus on infectious disease diagnostics. Education: Ph.D., University of Alberta (2009) M.Sc., Northwest University, Xi'an, China (1999) B.Sc., Northwest University, Xi'an, China (1997) Dr. Zhang's research explores binding-induced DNA assembly to create innovative diagnostic platforms. His laboratory specializes in developing fluorescent nanosensors for real-time detection in cellular environments, constructing target-triggered DNA nanomachines, and engineering novel affinity ligands through manipulation of functional nucleic acids. His work has made significant contributions to CRISPR-based diagnostics, particularly for SARS-CoV-2 detection, where his team has developed multiple point-of-care testing approaches that integrate nucleic acid amplification with CRISPR technology. Analysis of Dr. Zhang's recent publications reveals a strong research trajectory focused on integrating DNA nanotechnology with CRISPR systems to create streamlined diagnostic platforms. His work consistently addresses the challenge of moving complex molecular diagnostics from laboratory settings to point-of-care applications, with particular emphasis on sample preparation, signal amplification, and visual readout systems that eliminate the need for sophisticated equipment. The interdisciplinary nature of his research bridges chemistry, molecular biology, nanotechnology, and clinical medicine. Teaching: LABMP 551: Laboratory Research Methods LABMP 552: NSERC CREATE Course

Patrick Gunningمشاهده پروفایل

استاد

• Biological Chemistry
• Organic Chemistry
• Protein-Protein Interactions
• +۷ مورد دیگر

Patrick Gunning is a Professor at the University of Toronto (Mississauga campus), specializing in Biological Chemistry and Organic Chemistry. His research focuses on developing small molecule architectures to manipulate protein complexation events, particularly targeting aberrant protein interactions in diseases like cancer. Key areas include STAT3/STAT5 inhibition, histone deacetylase (HDAC) modulation, and molecular design strategies for cancer therapies. Research interests emphasize understanding protein-protein interaction 'hot spots' and designing drugs to suppress or enhance specific gene expressions. His work explores both organic and inorganic drug-like scaffolds to regulate cellular signaling pathways. Recent studies highlight novel treatments for leukemia, lymphoma, and brain metastases through targeted protein degradation and metabolic pathway manipulation. Over 50 publications demonstrate expertise in oncology, epigenetics, and drug discovery. Notable contributions include HDAC6-selective inhibitors, PROTAC-based degraders, and fluorine NMR methodologies for protein analysis. His interdisciplinary approach bridges organic chemistry, biochemistry, and clinical applications in precision medicine. Current projects investigate molecular mechanisms underlying cancer growth, with a focus on STAT signaling pathways and metabolic vulnerabilities. The lab also pioneers innovative drug delivery strategies using advanced spectroscopic techniques and chemical synthesis platforms.

Scott Napperمشاهده پروفایل

استاد

• Vaccine Development
• Prion Diseases
• Kinome Analysis
• +۳ مورد دیگر

Dr. Scott Napper is a Professor in the Department of Biochemistry, Microbiology & Immunology at the University of Saskatchewan, with a concurrent appointment as Senior Scientist at VIDO-Intervac. His work bridges structural biochemistry and immunology to address challenges in protein misfolding diseases, vaccine development, and host-pathogen signaling. Ph.D., Department of Biochemistry, 1999, University of Saskatchewan B.Sc. Honours, Department of Biochemistry, 1994, University of Saskatchewan Dr. Napper's research focuses on: Vaccine development for prion diseases and proteinopathies Kinome analysis for infectious disease mechanisms Peptide array technology for high-throughput signaling studies Science education outreach to secondary and undergraduate students Recent publications highlight his work in: Prion disease immunization strategies Host kinome responses to prebiotics Epitope immunogenicity prediction Comparative stress response analysis in livestock Scientific recognition includes: Three-time recipient of University of Saskatchewan Teaching Excellence Award His research program integrates computational approaches with experimental validation to identify therapeutic targets in: Infectious diseases of humans and animals Cancer signaling pathways Protein misfolding disorders Food contaminant toxicity

• Acute Myeloid Leukemia (AML)
• Epigenetics in Cancer
• Hematological Malignancies
• +۳ مورد دیگر

Tobias Berg is an Associate Professor of Oncology at McMaster University , affiliated with the Juravinski Cancer Centre (JCC) and the Centre for Discovery in Cancer Research (CDCR) . He leads the Translational Oncology Program , bridging clinical practice and basic research. His work focuses on understanding treatment resistance and relapse mechanisms in Acute Myeloid Leukemia (AML), leveraging epigenetic regulators, metabolic studies, and stem cell transplantation. Key roles include: Member of the Stem Cell and Cellular Therapy Program , specializing in allogeneic transplants and CAR T-cell therapy Principal investigator in clinical trials involving LSD1 inhibitors, venetoclax, and sorafenib Recipient of funding from the Boris Family Chair for Leukemia Research , Canadian Foundation for Innovation, and OICR Research Interests: Berg's lab investigates epigenetic drivers of leukemia relapse post-transplant, novel combination therapies, and biomarkers for early disease detection. Techniques include single-cell sequencing, metabolic profiling, and functional in vitro/in vivo models. His work also addresses residual disease detection through standardized flow cytometry panels (HARMONIZE initiative). Key Trends in Publications: Recent studies highlight: Role of IRF8 and LSD1 in AML drug sensitivity Impact of mixed donor chimerism on transplant outcomes Mechanisms linking metabolism and therapy resistance in FLT3-ITD AML Grants & Collaborations: Leads multicenter trials (e.g., SORMAIN and TRANSATRA) and collaborates with institutions like the Ontario Institute for Cancer Research . His lab is part of the McMaster Cancer Research Stem Cell Bank , collecting patient-derived samples for translational studies.

• Vaccinology
• Immunotherapy
• Adjuvant Development
• +۴ مورد دیگر

Dr. George Mutwiri is an Executive Director and Professor at the School of Public Health, University of Saskatchewan. His research focuses on vaccine development, adjuvant mechanisms, mucosal immunology, and innate immune responses in veterinary and human health contexts. He teaches advanced courses like PUBH 806.3 Public Health Biology and VACC 801.3 Vaccinology & Immunotherapeutics. Key research areas include: Development of novel vaccine adjuvants (e.g., PCEP) Immunobiology of Toll-like receptors (TLR9) Vaccine efficacy enhancement via formulation and delivery innovations Innate immune regulation in porcine intestines Recent grants (2014–2024) include NSERC Discovery grants totaling over $315,000 and CIHR funding for Indigenous mentorship programs. His work has led to groundbreaking insights into Zika virus impacts in porcine models and mechanisms of B-cell regulation in ruminants. Collaborative efforts span virology, immunogenetics, and translational vaccinology. Advising and grants highlight interdisciplinary collaboration, with significant contributions to training programs fostering Indigenous academic leadership. His research bridges basic science and clinical applications, addressing critical global health challenges in infectious disease prevention.

Louis-Éric Trudeauمشاهده پروفایل

استاد

• Neuropharmacology
• Neuroscience
• Dopamine Neurons
• +۵ مورد دیگر

Louis-Éric Trudeau is a Full Professor in the Department of Pharmacology and Physiology and Department of Neuroscience at the University of Montreal's Faculty of Medicine. He directs the Neural Signaling and Circuitry Research Group (SNC) and is a member of the Interdisciplinary Center for Brain and Learning Research (CIRCA). His laboratory focuses on understanding the fundamental mechanisms of dopamine neuron function and their role in Parkinson's disease. Education: BSc (Honors) in Psychology from Concordia University (1990) DEA in Neuroscience from University of Paris (1991) PhD in Neuroscience from University of Montreal (1994) Postdoctoral training at Iowa State University (1994-1996) Dr. Trudeau's research primarily investigates dopamine neurotransmission, with a focus on understanding how dopamine neurons function normally and why they degenerate in Parkinson's disease. His work spans cellular and molecular neuroscience, exploring mechanisms of neurotransmitter release, axonal arborization, mitochondrial function, and the role of the immune system in neurodegeneration. His laboratory employs a wide range of techniques including electrophysiology, electrochemistry, fluorescence imaging, confocal microscopy, and molecular biology approaches using normal and genetically modified mouse brain preparations. Analysis of Dr. Trudeau's recent publications reveals a strong focus on Parkinson's disease mechanisms, particularly examining the selective vulnerability of dopamine neurons, the role of mitochondrial function, immune system involvement, and neurotransmitter co-transmission. His work increasingly integrates immunological perspectives with traditional neuroscience approaches to understand Parkinson's disease pathogenesis. Dr. Trudeau has successfully secured substantial research funding from multiple sources including the Canadian Institutes of Health Research (CIHR), Natural Sciences and Engineering Research Council (NSERC), Parkinson Society Canada, Brain Canada Foundation, and the Michael J. Fox Foundation. His current projects span from basic cellular neuroscience to translational research aimed at developing new therapeutic strategies for Parkinson's disease. As an educator, Dr. Trudeau supervises numerous graduate students and postdoctoral fellows, teaching courses in cellular and molecular neuroscience, neuropharmacology, and the nervous system. His laboratory provides training in advanced neuroscience techniques to the next generation of researchers.