Alessandro Senes is a Professor at the Department of Biochemistry of the University of Wisconsin-Madison , where he joined in 2008 and was promoted to full professor in 2020. His research focuses on membrane protein structure and function , particularly the bacterial divisome and transmembrane interaction motifs like GAS-right . He is also the director of the Biophysics PhD program and the Molecular Biophysics NIH Training Grant . His laboratory employs a multi-disciplinary approach combining X-ray crystallography , genetic reporter assays , computational modeling , and in vivo analysis to study the structural organization of membrane proteins. He has developed the open-source MSL (Molecular Software Library) for advanced macromolecular modeling and the CATM method to predict GAS-right motif structures. His recent publications highlight computational advances in transmembrane dimer prediction, structural analysis of divisome proteins, and thermodynamic studies of hydrogen bonding. Key collaborators include experts in biophysics, molecular biology, and computational chemistry. Teaching roles include Biochem 551: Biochemical Methods and graduate seminars like Membrane Protein Structure and Function (Biochem 924) . His lab includes graduate students Joshua Choi , Samridhi Garg , and Tamalika Kar , plus undergraduates Emma Cushman and Alexander Vorobiov .








