- Biochemistry
- Mechanistic Enzymology
- Metalloenzymes
- +۶ مورد دیگر
Eduardus (Evert) Duin is a Professor in the Department of Chemistry and Biochemistry at Auburn University, specializing in mechanistic enzymology, metalloenzymes, and biochemical processes related to methane formation and oxidation. His research focuses on methyl-coenzyme M reductase (MCR) and heterodisulfide reductase (HDR), critical enzymes in methanogenic and methanotrophic archaea. University of Amsterdam – Ph.D. (1996) University of Georgia – Postdoctoral Associate (1996–1998) Max-Planck-Institute for Terrestrial Microbiology – Humboldt/MPI Fellow (1999–2002) His work investigates the biochemical activation mechanisms of MCR, particularly the role of electron bifurcation and ATP hydrolysis in its function, with implications for mitigating methane emissions in livestock and rice fields. His studies on HDR explore cofactor interactions and conformational changes in electron bifurcation processes. The research involves interdisciplinary approaches combining recombinant protein technology, site-directed mutagenesis, redox titrations, rapid-mix/rapid freeze techniques, and computational modeling. These methods aim to elucidate the structure-function relationships of nickel-containing coenzyme F430 and its role in methane production. Duin’s publications highlight collaborations with institutions like the University of Georgia, Max-Planck-Institute, and contributions to journals such as PNAS, Journal of Bacteriology, and Journal of the American Chemical Society.









