جستجوی استاد راهنمای دانشگاهی

• Biophysics
• Membrane Biology
• Molecular Biophysics
• +۳ مورد دیگر

Peter Pohl serves as University Professor at the Institute of Biophysics, Johannes Kepler University Linz, leading the Department of Molecular and Membrane Biophysics. His research program focuses on fundamental membrane processes with emphasis on ion channel behavior, proton conduction mechanisms, and development of optical tools for membrane manipulation. His primary research domains include Biophysics and Membrane Biology , specifically targeting: Regulation of ion channels by membrane domains Interfacial proton diffusion dynamics Photolipid-based optocapacitive stimulation Synthetic biomimetic pores using advanced polymers Nanodisc technology for membrane protein studies Light-powered molecular nanomotors His integrative approach combines experimental biophysics with theoretical modeling to address core questions in cellular membrane function. Recent publications reveal a pronounced shift toward optical control methodologies for membrane processes, including photolipid-induced action potentials and engineered fluorescent labeling systems. Concurrently, his group advances fundamental understanding of proton conduction mechanisms while developing synthetic ion channels through novel materials science approaches. No major scientific awards are documented in the provided information. Professor Pohl directs extensive research funding including EU Horizon projects and Austrian Science Fund grants. Current active projects (4) and completed initiatives (20) address membrane domain formation, ion channel regulation, antiviral compound development, and stress conduction through membranes. He has supervised one graduate researcher to date. His laboratory operates within the Institute of Biophysics at JKU, maintaining robust national and international collaborations evidenced by 59 scientific activities including conference presentations and organizational roles across European research networks.

• Neuroscience
• Motor Control
• Spinal Cord Injury
• +۵ مورد دیگر

Carmelo Bellardita is an Associate Professor in the Department of Neuroscience at the University of Copenhagen's Faculty of Health and Medical Sciences. His research focuses on understanding the neural mechanisms underlying motor control, with particular emphasis on spinal cord function, locomotion circuits, and the consequences of spinal cord injury. He is affiliated with the Kiehn Lab, a prominent neuroscience research group led by Professor Ole Kiehn. Position: Associate Professor Institution: University of Copenhagen Department: Neuroscience Research Focus: Neural circuits for movement, spinal cord physiology, locomotion control Contact: cbellardita@sund.ku.dk ORCID: https://orcid.org/0000-0001-6198-243X Lab Website: https://in.ku.dk/research/kiehn-lab Dr. Bellardita's research program investigates how neural circuits generate and regulate movement, with particular emphasis on spinal cord function. His work spans multiple levels of analysis from cellular and molecular mechanisms to systems-level circuit function and behavioral outcomes. Key research areas include organization of spinal locomotor circuits, sensory processing in motor control, pathophysiological changes following spinal cord injury, and development of therapeutic interventions for movement disorders. His laboratory frequently employs rodent models and techniques including electrophysiology, genetic manipulation, and behavioral analysis. Analysis of Dr. Bellardita's publication record reveals a strong trajectory of impactful research in motor neuroscience. His work demonstrates progression from fundamental studies of spinal cord circuitry to translational research with therapeutic implications. Recent publications show an expansion into neuroimmunology, investigating how immune cells interact with neural circuits to influence motor function. His research appears in top-tier journals including Nature, Nature Communications, and Science Translational Medicine, with his 2018 Nature paper on midbrain circuits controlling locomotion receiving over 300 citations. The broad dissemination of his work through news outlets, social media (including over 200 mentions on X for his most cited paper), and academic platforms demonstrates significant impact within and beyond the neuroscience community. Dr. Bellardita's research has received notable attention across multiple platforms. His work has been featured by numerous news outlets (totaling over 40 mentions across publications), shared extensively on social media including X (over 400 total mentions), Facebook, and Bluesky, and referenced on Wikipedia pages. His most cited paper has reached 590 readers on Mendeley, indicating substantial academic interest. This broad dissemination suggests his research has implications beyond basic neuroscience, potentially influencing clinical approaches to movement disorders and spinal cord injury rehabilitation. Dr. Bellardita maintains active collaborations within the neuroscience community, particularly with Professor Ole Kiehn's research group. His work demonstrates integration of multiple approaches to understand motor control systems, from single-cell transcriptomics to systems-level circuit analysis. The progression of his research from basic circuit mechanisms to translational applications suggests a comprehensive approach to addressing fundamental questions in neuroscience with potential clinical relevance. His recent foray into neuroimmunology represents an innovative direction that bridges traditionally separate fields to address complex questions about motor function.

• Laser Technology
• Optics
• Biophotonics
• +۴ مورد دیگر

Prof. Maria Dienerowitz is a Professor at Ernst Abbe University of Applied Sciences Jena specializing in laser technology and biophotonics. She teaches core courses including Laser Technology, Quantum Optics, and Vacuum Technology across Bachelor's and Master's programs while leading three major research initiatives: BioLOC (Carl-Zeiss-Stiftung-funded Lab-on-a-Chip system for molecular dynamics), OPTO (historical spectacle lens analysis with the German Optical Museum), and TOOLS (DFG-funded tailored optics for life sciences). Her research centers on advanced optical manipulation techniques including the ABEL trap for single-molecule studies without surface binding and holographic optical tweezers for nanoparticle control. Key focus areas encompass real-time enzyme kinetics of molecular motors like F-ATP synthase, single-molecule FRET dynamics , and nanoparticle characterization in biological contexts. This work bridges fundamental physics with biomedical applications through innovations in trapping methodology and optical instrumentation. Analysis of her 15 most recent publications reveals strong continuity in optical trapping methodologies with increasing biomedical applications since 2020. Her work demonstrates consistent contributions to single-molecule biophysics (particularly molecular motor studies), nanoparticle manipulation , and optical instrumentation development , with growing emphasis on life science interfaces evident in her Carl-Zeiss-Stiftung and DFG-funded projects. Prof. Dienerowitz currently oversees a research team comprising scientific staff members working across the BioLOC, OPTO, and TOOLS projects, including Dr. Jakub Malohlava (TOOLS), Maryam Shahrezaei (BioLoc), and Frederic Braun (TOOLS). Her laboratory infrastructure supports optical trap development, nanoparticle characterization, and molecular dynamics studies through equipment funded by the Carl-Zeiss-Stiftung and German Research Foundation.

Josepha Grewerمشاهده پروفایل

پژوهشگر

• Plant Development
• Synthetic Biology
• Optogenetics
• +۳ مورد دیگر

Josepha Grewer is a Researcher at the Institute of Synthetic Biology, Heinrich Heine University Düsseldorf, actively contributing to cutting-edge plant biology research. She is a core member of an HFSP collaboration project with Prof. Dr. Teva Vernoux (ENS Lyon), Dr. Siobhan Brady (UC Davis), and Dr. Richard Smith (John Innes Centre), focusing on deciphering self-organised 4D patterning in plant phyllotaxis using Physcomitrium patens as a model system. Her research integrates Plant Development, Synthetic Biology, and Data Science to pioneer optogenetic manipulation of phyllotactic patterning. By leveraging the single-cell apical meristem of Physcomitrium patens , she investigates fundamental mechanisms of self-organization in plant morphogenesis. This work intersects with the Institute's strategic research areas including Synthetic and Reconstruction Biology (RA 3) and Theoretical Plant Biology and Data Science (RA 4), emphasizing interdisciplinary approaches to optimize plant performance through developmental-metabolic interfaces. Funded by the Human Frontier Science Program (HFSP), her project exemplifies high-impact international collaboration addressing complex biological questions. The research utilizes institutional resources such as the Plant Metabolism and Metabolomics Facility and Imaging Platform, positioning her work at the forefront of synthetic plant biology with potential applications in edaphic adaptation and microbiota networks.

Holger Gerhardtمشاهده پروفایل

استاد

• angiogenesis
• tumour angiogenesis
• vascular plasticity
• +۷ مورد دیگر

Professor Holger Gerhardt is DZHK Professor for Experimental Cardiovascular Research at the Charité - Universitätsmedizin Berlin and Head of the Integrative Vascular Biology Laboratory at Max-Delbrück Center for Molecular Medicine in Berlin-Buch. He also serves as Vice-spokesperson of the DZHK Partnersite Berlin, Speaker of the DZHK Professors, and holds a Professorship at the Berlin Institute of Health. Additionally, he is the European coordinator for the Fondation Leducq transatlantic network of excellence ATTRACT and a member of the DZHK Board of Directors since July 2024. Professor Gerhardt's research focuses on unraveling the fundamental principles and molecular/genetic regulation of functional vascular network formation in development and disease. His work aims to advance understanding of mechanisms controlling the formation and patterning of vascular networks to inform therapeutic approaches for cardiovascular complications and tissue homeostasis restoration. He has made key discoveries including the mechanism of vascular lumen formation by inverse membrane blebbing under blood pressure, the identification of a phase transition in Notch signaling dynamics that switch blood vessel formation from branching to expansion, a role for YAP/TAZ signaling in controlling junctional dynamics and plasticity, and a role of primary cilia in endothelial cells sensitizing nascent vessels to the stabilizing activity of BMP under blood flow. His publication record demonstrates a consistent focus on vascular biology, angiogenesis, and cardiovascular research, with recent work expanding into areas such as bone healing, renal fibrosis, and immune-metabolic crosstalk in cardiovascular disease. His research combines advanced imaging techniques, genetic manipulation, and computational modeling to address fundamental questions in vascular development and disease. Chair Gordon Research Conference Angiogenesis (2015) Hooke Medal of the British Society for Cell Biology (2012) Judah Folkman Award of the North American Vascular Biology Organization (2011) Walter Flemming Medal of the German Society for Cell Biology (2009) Lister Institute of Preventive Medicine Prize (2008) Professor Gerhardt actively mentors PhD students and leads a research team at the Max-Delbrück Center. His laboratory receives funding from various sources including the German Center for Cardiovascular Research (DZHK) and the Fondation Leducq. He collaborates extensively with researchers across Europe and internationally, particularly through the ATTRACT network. The Integrative Vascular Biology Laboratory maintains state-of-the-art facilities for in vivo imaging, genetic manipulation, and computational modeling. The lab is part of the vibrant research community at the Max-Delbrück Center and collaborates closely with clinicians at the Charité hospital to translate basic research findings into potential clinical applications.

Brian Belardiمشاهده پروفایل

استادیار

• Molecular engineering
• Biotechnology
• Therapeutics and drug delivery
• +۸ مورد دیگر

Brian Belardi is an Assistant Professor in the Department of Chemical Engineering at the Cockrell School of Engineering, University of Texas at Austin, holding the Lyondell Chemical Company Endowed Faculty Fellowship in Engineering. His educational background includes: NIH Postdoctoral Fellow in Bioengineering, University of California, Berkeley (2014-2020) Ph.D. in Chemistry, University of California, Berkeley (2014) B.S. in Chemistry, Carnegie Mellon University (2008) Dr. Belardi's research centers on probing and re-programming biological barriers across length scales, combining molecular engineering, synthetic biology, and biophysics. His lab investigates: Extracellular Matrix Modifications: Studying post-translational modifications for diagnostics and biomaterials Epithelial Contacts & Engineering: Manipulating tight junctions to improve drug delivery Synthetic Cell Construction: Building cell-like assemblies for regenerative medicine Protein Switches: Developing light-activated controls for cellular mechanics Recent publications (2020-2023) reveal a strong trend toward synthetic biology approaches for engineering biological barriers, with emphasis on epithelial permeability, extracellular matrix dynamics, and synthetic cell systems. These works bridge fundamental biophysics with translational applications in drug delivery and tissue repair. His major recognitions include: David and Lucile Packard Foundation Packard Fellowship for Science and Engineering (2023) Advanced Drug Delivery Reviews Emerging Voices in Drug Delivery Award (2023) National Institutes of Health Maximizing Investigators’ Research Award (2021) Berkeley Postdoctoral Association Award (2019) National Institutes of Health Ruth L. Kirschstein NRSA Fellowship (2015) Young Investigator Award, University of Alberta Glycomics Centre (2014) Dr. Belardi mentors graduate students in an inclusive lab environment focused on interdisciplinary training. His research is supported by NIH grants, Packard Foundation funding, and industry partnerships. Current projects develop reagents to disrupt and repair biological barriers in cancer and inflammatory diseases. The Belardi Lab combines molecular engineering, chemical biology, and biophysics expertise to construct synthetic cells, detect extracellular matrix modifications, and engineer protein switches for therapeutic applications in drug delivery and regenerative medicine.

Benoît Ladouxمشاهده پروفایل

استاد

• Mechanobiology
• Cell Physics
• Tissue Mechanics
• +۵ مورد دیگر

Professor Benoît Ladoux serves as Principal Investigator leading the Tissue Mechanobiology Division at the Max Planck Center for Physics and Medicine, a joint research center of the Max Planck Institute for the Science of Light, Friedrich-Alexander-Universität Erlangen-Nürnberg, and Universitätsklinikum Erlangen. As a Humboldt Professor, he directs cutting-edge research at the physics-biology interface investigating how mechanical forces shape cellular and tissue behavior. His research program focuses on mechanobiology, exploring how cells detect and respond to mechanical signals in physiological and pathological contexts. Key areas include collective cell migration, tissue homeostasis, cell extrusion mechanisms, cellular monolayers as active nematics, cell rheology, and mechanical aspects of cell competition. His work bridges physics and biology to understand fundamental processes in morphogenesis, wound healing, aging, and cancer metastasis. Analysis of Professor Ladoux's recent publications reveals a strong emphasis on the physical principles governing tissue organization and mechanical force transmission. His work consistently explores how mechanical constraints influence cellular behavior across multiple scales, from single molecules to entire tissues, with particular attention to epithelial systems and their collective properties. Humboldt Professor Professor Ladoux leads an active research group investigating the physical basis of tissue organization and mechanical signaling. His laboratory develops innovative technologies to map and manipulate physical properties determining cell and tissue behavior, combining experimental approaches with theoretical modeling to explore chemical-physical signal interactions in living systems. His research team operates within the Tissue Mechanobiology Division, utilizing advanced methodologies to study mechanical forces in biological systems, with particular focus on epithelial tissues and their dynamic behaviors.

Tomas Laursenمشاهده پروفایل

دانشیار

• Plant Biochemistry
• Metabolons
• Phytochemical Production
• +۵ مورد دیگر

Tomas Laursen is an Associate Professor in the Department of Plant and Environmental Sciences at the University of Copenhagen, where he leads the Dynamic Metabolons research group within the Section for Plant Biochemistry. His work focuses on understanding the plasticity of biosynthetic membrane protein complexes (metabolons) for the production of phytochemicals in plants. Dr. Laursen's research spans plant biochemistry, biophysics, and metabolic engineering with a focus on: Organization and dynamics of enzyme complexes in plant metabolism Production mechanisms of bioactive plant compounds Cytochrome P450 systems and membrane protein behavior Engineering approaches to manipulate metabolic pathways His recent publications reveal a strong emphasis on understanding how plants organize their metabolic pathways through enzyme complexes (metabolons), with particular attention to conformational dynamics of key enzymes and spatial organization within plant cells. His research bridges fundamental biochemistry with practical applications in metabolic engineering. Dr. Laursen has secured significant research funding including: Novo Nordisk Foundation Emerging Investigator grant (2019-2024) Danish Council for Independent Research - Sapere Aude Starting Grant (2018-2022) Novo Nordisk Foundation Postdoc fellowship (2017-2019) He maintains active collaborations with researchers across multiple institutions, including experts in single molecule microscopy, neutron reflectometry, cryo-electron microscopy, and membrane protein technologies. His research group offers student projects focused on protein design and metabolic engineering approaches for plant metabolite production.

• Biophysics
• Cell Mechanics
• Optical Tweezers
• +۴ مورد دیگر

Younes Farhangibarooji is an Academic Staff member at the Biocomplexity section of the Niels Bohr Institute, University of Copenhagen. His research focuses on the intersection of biophysics, cell mechanics, and optical manipulation techniques, with significant contributions to understanding cellular structures and developing biomedical applications. His research interests span multiple cutting-edge areas in biophysics. Primary focus areas include: Actin cytoskeleton dynamics and cellular mechanics Optical tweezers technology and applications Viscoelastic properties of biological materials Nanoparticle delivery systems for cancer therapy Organoid development and morphogenesis mechanics His work combines experimental biophysics with computational analysis to unravel fundamental cellular processes. His publication record shows significant collaborative work, particularly with the research group of Professor Lene B. Oddershede. Notable contributions include the comprehensive Roadmap for optical tweezers published in Journal of Physics-Photonics (2023) and groundbreaking research on filopodia mechanics published in Nature Communications (2022). His work has garnered substantial attention, with multiple publications covered by news outlets and academic social media platforms. Dr. Farhangibarooji's research demonstrates strong interdisciplinary connections between physics, biology, and medical applications, particularly in cancer research and regenerative medicine approaches using organoid models.

• Genetic modification
• Mouse models
• CRISPR/Cas9
• +۵ مورد دیگر

Javier Martin Gonzalez serves as a Doctor Research consultant and manager of the Transgenic Core Facility at the University of Copenhagen's Faculty of Health and Medical Sciences. With expertise in genetic modification and mouse model development, he leads a critical research support unit that provides essential services to the scientific community. His research interests center on genetic modification techniques, particularly CRISPR/Cas9 applications, mouse model development, embryonic stem cell culture and modification, and assisted reproduction technologies. The Transgenic Core Facility maintains an extensive cryobank with over 750 mouse strains, supporting researchers through embryo manipulation, stem cell derivation, and specialized breeding programs. His recent publication record demonstrates a strong focus on developmental biology, genome editing, and reproductive science, with multiple high-impact publications in 2024-2025 across journals including Cell Reports, Nature Communications, and Heliyon. His work spans from fundamental DNA repair mechanisms to applications in fertility and embryonic development. The Transgenic Core Facility under his management represents a vital resource for researchers at the University of Copenhagen, providing specialized expertise in mouse model generation and maintenance that supports numerous research projects across the institution.

• RNA Biology
• Virology
• Antiviral Immunity
• +۴ مورد دیگر

James Burke serves as an Assistant Professor in the Department of Molecular Microbiology at the University of Florida's Scripps Research campus in Jupiter, Florida. His laboratory investigates RNA biology during pathogenic viral infections using biochemical, molecular, and advanced microscopy approaches. Dr. Burke's research focuses on RNA biology in viral pathogenesis , particularly examining the OAS/RNase L pathway during infections by dengue virus, Zika virus, SARS-CoV-2, and influenza A. His work reveals how viral infections manipulate host mRNA decay pathways, induce ribonucleoprotein condensates, and disrupt nuclear-cytoplasmic transport. Key findings include RNase L-mediated formation of specialized RNA granules that sequester viral RNA and regulate antiviral responses. Analysis of his 15 most recent publications shows a dominant focus on viral-host RNA interactions (80% of articles), with significant contributions to understanding stress granule dynamics, PKR regulation, and mRNA decay mechanisms during infection. His work bridges fundamental RNA biochemistry with translational virology. Dr. Burke currently leads an active NIH/NIGMS-funded project titled "Understanding the OAS/RNase L pathway during pathogenic viral infections" as Principal Investigator. His lab maintains strong collaborative ties with clinical researchers, evidenced by co-authorship on studies examining stroke outcomes, cardiac care disparities, and cognitive aging.