جست‌وجوی استاد و پژوهشگر

Chris John Potterمشاهده پروفایل

استاد

• Neuroscience
• Olfaction
• Insect Neurobiology
• +۳ مورد دیگر

Dr. Chris John Potter is a Professor of Neuroscience at Johns Hopkins University School of Medicine, where he has been faculty since 2010. His research program investigates neural mechanisms of olfaction in disease-transmitting insects, particularly malaria mosquitoes. Dr. Potter leads the Christopher Potter Lab, developing genetic tools like the Q-system to study sensory processing and behavior. Education: Ph.D. in Genetics, Yale University (2002) B.A. in Molecular and Cell Biology, University of California, Berkeley (1996) Postdoctoral Fellowship in Neuroscience, Stanford University (2010) Research focuses on: Neural circuit basis of olfactory behaviors in Drosophila and mosquitoes Development of genetic tools for neural manipulation Chemosensory mechanisms guiding mosquito host-seeking and oviposition Translational applications for vector-borne disease control Recent publications emphasize mosquito neurobiology, genetic tool development, and olfactory coding mechanisms. His work consistently integrates molecular genetics with systems neuroscience approaches. Honors and Awards: NIH R21 Grants (NIAID 2018, NINDS 2015) Johns Hopkins Discovery Award (2017) Malaria Research Institute Pilot Award (2015) Whitehall Foundation Grant (2011) Damon Runyon Fellowship (2003) The Potter Lab ( potterlab.johnshopkins.edu ) develops transgenic approaches to study sensory processing. Current projects investigate mosquito olfactory circuits using calcium imaging, single-cell sequencing, and behavioral assays. Dr. Potter collaborates with public health researchers to translate basic discoveries into vector control strategies.

Holger Bierhoffمشاهده پروفایل

دانشیار

• Epigenetics
• Aging Research
• Non-coding RNA
• +۶ مورد دیگر

Holger Bierhoff serves as an Associate Group Leader at Friedrich Schiller University Jena with an associated position at the Leibniz Institute on Aging (FLI), operating from the Center for Molecular Biomedicine (CMB). His research group maintains a guest status collaboration with FLI while being primarily based at the university. Professor Bierhoff's research focuses on epigenetics of aging, specifically investigating how non-coding RNAs form RNA:DNA triplex structures to regulate chromatin landscape. His lab has developed novel molecular tools to detect and characterize these triplex structures genome-wide, examining how they compete with protein binding or alternative nucleic acid structures at target sites. Current work explores connections between ribosome biogenesis, nucleolar function, and aging processes using human and mouse cell models. His publication record shows consistent high-impact output, with multiple significant papers in 2024 including research on RNA:DNA triplexes as epigenetic communication mechanisms, rRNA synthesis and longevity in C. elegans, and breast cancer mechanisms. His work appears in prestigious journals such as Nature Communications, Cell Reports, and Nucleic Acids Research. Professor Bierhoff leads two major funded projects: AgingComb (funded by European Regional Development Fund) investigating genomic alterations through high-throughput DNA analysis, and 'Nucleolus as a target' (funded by European Social Fund) developing nucleolar changes as biomarkers for healthy aging. Both projects involve interdisciplinary collaborations between university researchers and clinical partners. His lab maintains active supervision of doctoral, master's, and bachelor students, creating a collaborative research environment focused on cutting-edge epigenetic mechanisms in aging. The group is embedded within the Zentrum für Alternsforschung Jena (ZAJ) and the Leibniz Research Alliance Resilient Ageing, providing students with access to advanced facilities and interdisciplinary networks.

• Epigenetics
• Chromatin Biology
• Environmental Epigenetics
• +۴ مورد دیگر

Daphne Selvaggia Cabianca is a Group Leader at the Cabianca Lab , affiliated with Helmholtz Munich under the Functional Epigenetics (IFE) group . Her research focuses on understanding how environmental inputs modulate chromatin state, spatial organization, and function using the model organism C. elegans . Research Interests Epigenetic responses to environmental stress Chromatin 3D organization and gene regulation Nutrient and temperature effects on chromatin Stress memory mechanisms Key Techniques CRISPR-Cas9 genetic editing ChIP, DamID, ATACseq RNAseq and organismal stress assays Her work explores the interplay between environmental stimuli and chromatin dynamics across life stages, from development to aging. This research has implications for diseases like obesity, type 2 diabetes, and cancer with strong environmental links. Recent publications highlight her contributions to understanding fasting-induced chromatin reorganization, ferroptosis suppression in neuronal development, and environmental stress memory mechanisms. Collaborative lab members include doctoral researchers and postdocs working on various aspects of chromatin biology and C. elegans genetics. Lab Members Iratxe Estivariz (Postdoc) Fernanda Pabst (Doctoral Researcher) Carole Zaratiegui (Doctoral Researcher) Yuri D'Alessio (Doctoral Researcher) Lorenz Pudelko (Doctoral Researcher)

Antonio Giraldezمشاهده پروفایل

استاد

• Developmental Biology
• Gene Expression Regulation
• Genomics
• +۹ مورد دیگر

Antonio Giraldez is the Fergus F. Wallace Professor of Genetics at Yale School of Medicine, where he has led his research laboratory since 2007. He served as Director of Graduate Studies (2012-2016) and Chair of the Genetics Department (2017-2023). His academic appointments span multiple departments and centers including Biochemistry, Quantitative Biology, Biophysics and Structural Biology (BQBS), the Center for RNA Science and Medicine, Yale Cancer Center, Yale Center for Genomic Health, Yale Combined Program in the Biological and Biomedical Sciences (BBS), and the Yale Stem Cell Center. Professor Giraldez's research focuses on understanding the regulatory code that governs gene expression during vertebrate development after fertilization. His lab investigates four interconnected areas: genome activation during the maternal-to-zygotic transition, post-transcriptional regulation of gene expression, modeling of therapeutic mRNA design, and modeling of gene regulatory networks. Using zebrafish as a primary model organism combined with advanced genomic, computational, and imaging approaches, his lab has made significant contributions to understanding how transcription factors activate the embryonic genome and how RNA regulatory elements control mRNA stability and translation. Analysis of Professor Giraldez's recent publications reveals a strong focus on the molecular mechanisms of embryonic development, particularly the maternal-to-zygotic transition where control of development passes from maternal to embryonic factors. His work increasingly integrates high-throughput genomic approaches with computational modeling to decode regulatory elements in RNA that determine stability, translation efficiency, and tissue-specific expression - knowledge directly applicable to therapeutic mRNA design for gene therapy and vaccines. Scientific Awards and Honors: HHMI Faculty Scholar (2016) Blavatnik Award for Young Scientists National Finalist (2016) Vilcek Prize for Creative Promise in Biomedical Science (2014) Pew Scholar in Biomedical Sciences (2008) NYAS Blavatnik Young Investigator Award Finalist (2007) Professor Giraldez has established a productive research program with consistent funding and publication in top-tier journals. His lab maintains active collaborations with researchers across Yale and beyond, as evidenced by his frequent co-authorship with scientists from multiple departments. He has trained numerous students and postdocs who have gone on to independent research careers. The Giraldez Lab maintains a diverse team of researchers working at the intersection of developmental biology and genomics. The lab provides extensive resources including published datasets, computational tools like CRISPRscan, and detailed genomic annotations available through their data repository. Professor Giraldez's research program continues to advance our understanding of fundamental gene regulatory mechanisms with implications for both basic science and therapeutic applications.

• Synthetic Biology
• Gene Editing
• Genomics
• +۶ مورد دیگر

Farren Isaacs is a Professor of Molecular, Cellular and Developmental Biology at Yale School of Medicine with extensive affiliations across Yale University. His primary appointments include the Department of Molecular, Cellular and Developmental Biology, Microbiology, and the Yale Cancer Center. He also participates in the Center for RNA Science and Medicine, Genomics, Genetics and Epigenetics Program, Molecular Cell Biology, Genetics and Development, Yale Combined Program in the Biological and Biomedical Sciences (BBS), and Yale Ventures. Dr. Isaacs received his BS in Bioengineering from the University of Pennsylvania, followed by MS and PhD degrees in Biomedical Engineering and Bioinformatics from Boston University. He completed postdoctoral training at Harvard Medical School before establishing his independent research program at Yale. His research focuses on developing and applying genome engineering technologies to understand and reprogram biological systems. His lab has pioneered approaches like MAGE (Multiplex Automated Genome Engineering) and has made significant contributions to genome recoding, CRISPR-based editing, and synthetic genetic circuit design. Recent work includes engineering genomically recoded organisms with simplified genetic codes and developing precision multiplexed base editing techniques with potential therapeutic applications. Dr. Isaacs' publication record demonstrates sustained innovation in synthetic biology and genome engineering, with high-impact papers spanning from foundational work in the early 2000s to multiple 2025 publications in journals like Nature, Nature Communications, and Science. His research trajectory shows a clear progression from developing basic genome engineering tools to applying these technologies to increasingly complex biological problems. Beckman Young Investigator Award (2012) Rising Young Stars of Science (2008) Dr. Isaacs maintains an active research program with multiple current grants supporting work in genome engineering and synthetic biology. His lab trains graduate students and postdoctoral fellows in cutting-edge genomic technologies while fostering interdisciplinary collaborations across Yale and with external institutions. The lab operates across two locations - at Yale's main Science Hill campus and at the West Campus facility. The Isaacs Lab focuses on developing next-generation genome engineering technologies and applying them to fundamental biological questions and potential therapeutic applications. Current research directions include expanding the genetic code, developing precision editing tools, and creating synthetic biological systems with novel properties and enhanced biocontainment features.

• Vascular Biology
• Endothelial Cell Biology
• Macrophage Biology
• +۹ مورد دیگر

Dr. Yajaira Suarez is the Anthony N. Brady Professor of Comparative Medicine and Deputy Chair of the Department of Comparative Medicine at Yale School of Medicine. She also holds a secondary appointment as Professor of Pathology and is an active member of the Yale Cancer Center, Vascular Biology and Therapeutics Program, and Yale Center for Molecular and Systems Metabolism. Dr. Suarez earned her BS and PhD in Biochemistry and Molecular Biology from Universidad Autonoma de Madrid (1995, 2001), followed by postdoctoral training at Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid (2002-2005) and Yale University School of Medicine (2005-2009). She began her independent research career at New York University School of Medicine in 2009 before joining Yale in 2013. Her research program focuses on understanding novel regulatory mechanisms in endothelial cell and macrophage functions, particularly examining non-coding RNAs, metabolic rewiring, immunometabolism, and cholesterol regulation. This work has significant implications for atherosclerosis, cancer, and metabolic diseases. Her publication record demonstrates consistent high-impact research in top-tier journals including Nature Communications, Journal of Clinical Investigation, and PNAS. Dr. Suarez's research output shows a clear focus on the intersection of vascular biology and metabolism, with recent publications (2021-2025) emphasizing endothelial cell metabolism, macrophage immunometabolism, and non-coding RNA regulation in cardiovascular and metabolic diseases. Her work has established her as a leader in understanding how metabolic pathways regulate vascular function and inflammation. Recipient of the 2025 Judah Folkman Award in Vascular Biology Elected member of Connecticut Academy of Science and Engineering (2022) Werner Risau New Investigator Award in Vascular Biology Kingsley Award in Medical Research from Yale School of Medicine Fellowship-Grant Award from CNIC P3+3 programme for Post-doctoral Careers in Biomedicine Dr. Suarez maintains active collaborations with numerous researchers at Yale and internationally. Her lab employs a multidisciplinary approach combining molecular and cellular biology, biochemistry, and genetically modified mouse models. Her recent work has significant translational potential for developing novel therapies for cardiovascular diseases, cancer, and metabolic disorders.

• RNA Biology
• Computational Biology
• Hematologic Neoplasms
• +۵ مورد دیگر

Toma Tebaldi is an Assistant Professor Adjunct in the Medical Oncology and Hematology department at Yale School of Medicine and a member of the Yale Cancer Center. His interdisciplinary work bridges computational biology and cancer research, with a focus on RNA mechanisms in hematologic malignancies. Dr. Tebaldi maintains affiliations with multiple research programs including Genomics, Genetics, and Epigenetics, and Internal Medicine at Yale. Dr. Tebaldi's educational background includes a PhD in Information and Communication Technology from the University of Trento (2010), an MSc in Biotechnologies - Bioinformatics from University of Milano Bicocca (2006), and a BSc in Biotechnologies from the same institution (2003). His training includes postdoctoral fellowships at University of Trento, EMBO Short Fellowship at University of Edinburgh, and international internships at Harvard Medical School, University of Edinburgh, and University of Sheffield. His research focuses on RNA molecular mechanisms underlying disease dysregulation, combining experimental and computational approaches. Key areas include alternative splicing, non-coding RNA binding, mutant RNA binding proteins, RNA modifications (epitranscriptome), translation dynamics, and single-cell expression data. This work has significant implications for understanding and treating hematologic cancers. Dr. Tebaldi's publication record shows consistent output in high-impact journals from 2022-2025, with research spanning cancer biology, RNA mechanisms, and computational approaches. His work demonstrates increasing sophistication in integrating single-cell technologies with traditional molecular biology techniques to address complex questions in cancer biology. Italian National Scientific Qualification as Associate Professor in Applied Biology (2021) Italian National Scientific Qualification as Associate Professor in Molecular Biology (2020) Yale YCCEH Pilot and Feasibility Program Award (2018) RNA Society Travel Award: RNA2016, Kyoto (2016) EMBO Travel Grant Award: Protein synthesis and translational control (2015) Dr. Tebaldi serves as Associate Editor for Frontiers in Genetics - Computational Biology and as a reviewer for PRIN 2020 MIUR. His membership in the Yale Center for Biomedical Data Science and Yale Cancer Center provides access to extensive collaborative networks and resources. His research program benefits from interdisciplinary connections between computational biology, cancer genomics, and clinical hematology/oncology. Through his Italian Society of Yale Students and Affiliates board membership and Visiting Professor appointments at University of Trento, Dr. Tebaldi maintains strong international connections that enrich his research program and provide opportunities for student exchanges and collaborative projects across continents.

Nuttida Rungratsameetaweemanaمشاهده پروفایل

استادیار

• Neural computations
• Cognitive neuroscience
• Computational neuroscience
• +۶ مورد دیگر

Nuttida Rungratsameetaweemana is an Assistant Professor in the Department of Biomedical Engineering at Columbia University's Fu Foundation School of Engineering and Applied Science. She also serves as a Provost Research Fellow at Columbia University, demonstrating her significant research contributions early in her academic career. NuttidaLab, her research group, focuses on integrating computational and experimental approaches to investigate the neural computations underlying complex cognitive functions in both health and disease. The lab's research spans several key areas including learning mechanisms, decision-making processes, and social behavior, with particular emphasis on understanding how these cognitive functions become disrupted in neurological and neuropsychiatric disorders. The lab has developed several important computational neuroscience tools including NeuralDecoder for representational similarity analysis, state_space_analysis for modeling neural dynamics, MARLAX for multi-agent reinforcement learning, and dynamax for state space modeling. These tools reflect the lab's commitment to developing robust analytical frameworks that can be widely adopted by the neuroscience community. NuttidaLab maintains an active GitHub presence with multiple repositories that demonstrate the lab's focus on open science and reproducible research. The lab's work combines cutting-edge computational approaches with experimental neuroscience to develop a deeper understanding of brain function. The lab actively seeks talented students and researchers interested in interdisciplinary work at the intersection of engineering, neuroscience, and computational science. Professor Rungratsameetaweemana's research represents an important bridge between theoretical computational models and experimental neuroscience, with significant potential for advancing our understanding of both healthy brain function and neurological disorders.

Jens Bohneمشاهده پروفایل

دانشیار

• RNA Biology
• Virology
• Gene Expression Regulation
• +۴ مورد دیگر

Dr. Jens Bohne serves as Principal Investigator at Hannover Medical School (MHH), leading the Bohne Lab within the Institute of Virology. His research centers on RNA biology and gene expression regulation, with dual focus on herpesviral RNA mechanisms and non-coding mutations in human diseases. Research Focus: The lab investigates how viral gene expression and non-coding mutations reveal fundamental cellular processes. Key areas include: Herpesviral RNA expression regulation (particularly KSHV) Pathomechanisms of non-coding mutations in hemophilia, Wilson disease, and immunodeficiencies Advanced RNA analysis techniques including northern blots, CRISPR editing, and antisense oligonucleotide therapies Publication Trends: Recent work (2014-2021) demonstrates strong interdisciplinary integration across virology, genetics, and clinical medicine. Publications in journals like PLoS Genetics and Nucleic Acids Research highlight translational approaches connecting RNA mechanisms to therapeutic interventions for genetic disorders and viral pathogenesis. Research Team: The lab includes Dr. Carolin Vogt (herpesviral gene expression specialist) and Dr. Simon A. Krooss (non-coding mutations in liver diseases), utilizing molecular biology techniques alongside CRISPR and viral vector technologies for gene editing studies.

Lars Maegdefesselمشاهده پروفایل

استاد

• vascular disease
• atherosclerosis
• aortic aneurysm
• +۴ مورد دیگر

Lars Maegdefessel is a Professor of Molecular Vascular Medicine at the Technical University Munich (TUM), School of Medicine and Health. He leads the Experimental Vascular Medicine unit at Klinikum rechts der Isar and serves as a DZHK Junior Group Leader. His research focuses on the therapeutic and biomarker potential of non-coding RNAs in vascular diseases including atherosclerosis, aortic aneurysm, and related vascular pathologies. Dr. Maegdefessel's research interests center on the role of non-coding RNAs in vascular diseases, with particular focus on the vulnerability of atherosclerotic vascular lesions and the progression and rupture of abdominal aortic aneurysms. His laboratory utilizes unique human biobank materials and various pre-clinical experimental models to investigate novel molecular approaches for combating cardiovascular diseases. His work spans from basic research on microRNAs, long non-coding RNAs, and circular RNAs to translational applications in vascular medicine. Analysis of Dr. Maegdefessel's publication record reveals a strong focus on non-coding RNA mechanisms in vascular pathology, with particular emphasis on atherosclerosis stabilization, aneurysm development, and vascular inflammation. His research has evolved from basic miRNA characterization to sophisticated therapeutic applications including targeted delivery systems and novel biomarker discovery. The publications demonstrate a consistent trajectory toward clinical translation of RNA-based vascular therapeutics. ERC Consolidator Grant (2023) Russel Ross Award from American Heart Association (2023) Heisenberg Professorship of German Research Foundation (2016) Werner Risau Award of American Heart Association (2016) ERC Starting Grant (2015) Prince Daniel Research Award of Swedish Heart and Lung Foundation (2014) Ragnar Söderberg Fellowship in Medicine (2014) Dr. Maegdefessel's research program includes extensive collaboration with international teams and utilizes advanced methodologies including RNA sequencing, microarrays, proteomics, and epigenomic analyses. His laboratory investigates ncRNA function in human vascular tissues and pre-clinical models, with recent work focusing on artery-on-a-chip technology and novel therapeutic delivery systems for vascular applications.

Michael Brechtمشاهده پروفایل

استاد

• Neuroscience
• Somatosensory Cortex
• Memory Consolidation
• +۶ مورد دیگر

Michael Brecht is a Professor at Humboldt University of Berlin, Faculty of Life Sciences, Department of Biology. His research focuses on neural mechanisms underlying somatosensory processing, memory consolidation, kinship behavior, and social play. He leads a research group investigating brain circuits related to these functions, with particular emphasis on the lateral septum, periaqueductal gray, and somatosensory cortex. Professor Brecht's research interests include: Neural circuits for somatosensory processing and body map representation Mechanisms of memory consolidation from synapses to systems Neural basis of kinship behavior and social recognition Neurobiology of social play and vocal communication Spatial coding and navigation systems in the brain His recent publications reveal a consistent focus on understanding how specific brain regions encode social and sensory information. Brecht's work frequently employs advanced techniques including electrophysiology, calcium imaging, optogenetics, and large-scale neural recording to investigate circuit mechanisms. A notable trend in his research is the investigation of sex differences in neural processing, particularly in genital somatosensory representation, and the identification of specialized neural architectures for social behaviors like kinship recognition. Scientific contributions include: Discovery of nepotopy (topographical representation of kin/nonkin) in the lateral septum Demonstration of sex differences in genital cortex representation Identification of glycine-dependent mechanisms in social play behavior Mapping of vocalization-related activity in brainstem nuclei Elucidation of perirhinal input mechanisms for neocortical learning Professor Brecht actively mentors students and collaborates with researchers across multiple institutions. His laboratory investigates both fundamental neural mechanisms and their implications for understanding social behavior. Current work appears focused on understanding the molecular and circuit-level basis of kinship memory and the neural substrates of social play behavior across development.

• Gender and Technology
• Intersectional Equality
• Inclusive Design
• +۳ مورد دیگر

Dr. Siân Brooke serves as an Assistant Professor and MacGillavry Fellow at the Digital Interactions Lab (DIL), University of Amsterdam. Her interdisciplinary work bridges data science and critical social research to investigate gender and intersectional equality in technology interactions, with a focus on ethical AI and human-centered computing systems. Her research centers on gender dynamics in technology , inclusive platform design , and systemic bias mitigation in digital environments. Brooke employs mixed-methods approaches combining large-scale data analysis of platforms like GitHub and Stack Overflow with ethnographic studies and controlled experiments. Key themes include how programming styles reflect gender differences without impacting quality, how online labor markets perpetuate discrimination through design choices, and how internet memes reinforce toxic masculinity in physical tech spaces like hackathons. Analysis of her recent publications reveals consistent focus on exposing and redesigning discriminatory mechanisms in technology. Her 2024 work demonstrates how platform interventions (community composition, identity flairs) can reduce hiring discrimination in online labor markets, while her GitHub study proves gendered programming styles exist but don't correlate with code quality. A unifying thread across all work is the development of concrete design solutions for more equitable technology ecosystems. Dr. Brooke's recognition includes: NWO Veni Grant (€320,000) for "Human-Centered Code: Building Accessible IDEs for Neurodiverse Women in Computing Education" Leverhulme Early Career Fellowship examining gender in collaborative computing environments She actively mentors through hiring a PhD candidate for her NWO project (closing November 2024) and serves on the Open Tech Fund Advisory Council guiding global internet freedom initiatives. Her commitment to research transparency led to implementing Open Science Badges as Associated Editor for Data and Ethics, recognizing reproducible practices in scholarly work. Brooke leads the Digital Interaction Lab's research on technology equity, including the "Mock-Freelancer.com" experimental platform testing anti-discrimination interventions in online labor markets. Her lab collaborates across disciplines to develop accessible computing environments and policy recommendations for inclusive technology design, with recent work featured in LSE Research explaining gender disparities in programming.

• Fungal Biology
• RNA-binding Proteins
• Protein Secretion Mechanisms
• +۶ مورد دیگر

Michael Feldbrügge is a prominent researcher at Forschungszentrum Jülich's Bioeconomy Science Center (BioSC) in Germany, where he leads investigations into fungal biology with a particular focus on Ustilago maydis as a model organism. His work bridges fundamental molecular mechanisms with biotechnological applications, establishing him as a key contributor to sustainable bioeconomy research. Dr. Feldbrügge's research interests center on RNA-binding proteins and their role in mRNA transport, particularly the Rrm4-mediated transport system in fungi. His laboratory investigates unconventional protein secretion pathways, especially the Cts1 chitinase secretion mechanism in Ustilago maydis , which has significant implications for biopharmaceutical production. His work extends to microbial triglyceride production, plant-microbe interactions, and the development of fungal-based diagnostic tools. The research demonstrates strong translational potential, connecting basic fungal biology with applications in sustainable energy, agriculture, and medical diagnostics. Analysis of his recent publications reveals a consistent research trajectory focused on RNA-protein interactions in fungal systems, with increasing emphasis on sustainable biotechnology applications. His work shows a sophisticated integration of molecular biology, microbiology, and systems approaches to address challenges in bioeconomy. The publication record demonstrates significant international collaboration, with co-authors from institutions across Europe, North America, and South America. Dr. Feldbrügge has made substantial contributions to understanding endosomal mRNA transport mechanisms in fungi, demonstrating evolutionary conservation of these processes across fungal phyla. His work on unconventional protein secretion pathways has opened new avenues for biopharmaceutical production, while his recent research on microbial triglyceride production offers promising alternatives to conventional plant oils.