Secretory Pathways Professors and Supervisors | ApplySharif

جست‌وجوی استاد و پژوهشگر

استاد راهنما، استاد دانشگاه یا پژوهشگر مناسب برای مسیر پژوهشی‌تان را پیدا کنید و با او ارتباط بگیرید.

نمایش ۱-۱۵ از ۵۶۱ استاد راهنما

اطلاعات این پروفایل‌ها از صفحات عمومی دانشگاه‌ها جمع‌آوری شده و ممکن است به‌روز نباشد.

Andre Levchenkoمشاهده پروفایل

استاد

Yale UniversityUnited States

Andre Levchenko is the John C. Malone Professor of Biomedical Engineering at Yale University, with secondary appointments in the Department of Neurosurgery and affiliations with the Cancer Signaling Networks, Immunology, and the Yale Program in Neurodevelopment and Regeneration. His research focuses on systems biology, signal transduction, and cell-cell communication, utilizing microfluidics and computational modeling to study cancer progression, stem cell behavior, and neurological disorders. PhD, Columbia University MEng, Moscow Institute of Physics and Technology Levchenko's work explores how cells process dynamic signals to make critical decisions, particularly in glioblastoma migration, organoid development, and cardiovascular tissue engineering. His lab develops innovative microfluidic platforms and mathematical models to dissect multicellular communication and signaling networks. Recent publications highlight his contributions to understanding YAP-driven cancer invasion , NOTCH signaling in angiogenesis , and metabolic regulation of hypoxia responses . He has pioneered methods for organoid modeling and single-cell analysis , advancing precision in biological signaling studies. Scientific Awards : Computational Molecular Biology Post-Doctoral Fellowship (Burroughs Wellcome Fund) National Academies Keck Futures Conference Invitee Distinguished Guest Lecturer, University of Virginia American Asthma Foundation Early Excellence Award Fellow, American Institute for Medical and Biological Engineering Levchenko leads the Levchenko Lab at the Yale Systems Biology Institute, collaborating with institutions like Mayo Clinic and Yale Cancer Center. His research has received recognition in Faculty of 1000 and multiple journal highlights.

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Vadim Cherezovمشاهده پروفایل

استاد

University of Southern CaliforniaUnited States

Vadim Cherezov, the Ester Dornsife Chair in Biological Sciences and Professor at the University of Southern California (USC), leads groundbreaking research in membrane protein structure and function. Affiliated with the Bridge Institute, Department of Chemistry, and Michelson Center for Convergent Bioscience, his work focuses on GPCRs, ion channels, and transporters—critical targets for drug discovery. His team leverages advanced techniques like Lipidic Cubic Phase (LCP) and Serial Femtosecond Crystallography (SFX) at XFEL facilities to solve high-resolution structures under physiological conditions. Institutional Affiliations: Bridge Institute, USC Michelson Center, Department of Chemistry, Department of Pharmacology and Pharmaceutical Sciences. Key Collaborations: Katritch Lab, Kuhn Lab, NIH, European XFEL. His research explores the role of lipids in modulating GPCR function, addressing diseases like Alzheimer’s, diabetes, and cancer. By solving the structure of the A 2A adenosine receptor via sulfur SAD phasing at XFEL, Cherezov’s lab demonstrated de novo phasing without heavy atoms. This breakthrough enables structural studies of previously intractable membrane proteins. Scientific Awards & Grants: NIH R01 GM108635, U54 GM094618, U54 GM094599, R01 GM095583 Science Signaling Breakthroughs of the Year (2014) Cherezov mentors a dynamic team, including postdocs (e.g., Dong-Gyun Kim), graduate students (e.g., Behnaz Davoudinasab), and alumni (e.g., Benjamin Stauch at Eli Lilly, Nairie Michaelian at Genentech). His lab’s publications span Nature , Science , and Cell , with recent work on Science Advances (2025) addressing ABEL-FRET for GPCR dynamics.

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Kelly Arnoldمشاهده پروفایل

دانشیار

University of Michigan-Ann ArborUnited States

Kelly Arnold is an Associate Professor in the Department of Biomedical Engineering at the University of Michigan. Her research integrates systems engineering principles with immunology to investigate variability in immune responses across infection, vaccination, and injury, with a focus on computational modeling and clinical translation. Research Focus Systems-level immune response modeling Vaccination and antibody functionality Vaginal microbiome-host interactions Chronic lung disease progression Computational serology and proteomics Recent Work Her 2025 studies examine SARS-CoV-2 vaccination responses in cancer patients and computational frameworks for vaginal probiotics. Earlier works (2024-2007) span COPD progression, lupus fibrosis, HIV susceptibility, and tissue engineering for fertility preservation. Methodologies include proteomic profiling, network modeling, and microfluidic systems.

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Steven L'Hernaultمشاهده پروفایل

استاد

Emory UniversityUnited States

Spermatogenesis
Cell Biology
Genetics
+۲ مورد دیگر

Steven L'Hernault is Professor and Chairman of Biology at Emory University, where he leads research on cellular and developmental processes using Caenorhabditis elegans models. His laboratory investigates molecular mechanisms underlying spermatogenesis, focusing on genetic controls of sperm development and function. The L'Hernault Lab studies highly conserved genome protection mechanisms in germ lines using genetic, molecular, and biochemical approaches. Key research areas include secretory vesicle function, membrane protein interactions, and ubiquitin ligase activity during sperm differentiation. Recent publications examine paternal epigenetic inheritance pathways and palmitoyltransferase functions in spermiogenesis. The lab maintains an extensive collection of C. elegans mutants with defective spermatogenesis to study fundamental cellular processes.

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Markus Meissnerمشاهده پروفایل

استاد

Ludwig Maximilian University of MunichGermany

Prof. Dr. Markus Meissner is a Professor at the Faculty of Veterinary Medicine, Ludwig Maximilian University of Munich, leading the Chair of Experimental Parasitology. His research focuses on the molecular mechanisms of host cell invasion and modulation by Apicomplexan parasites, particularly Toxoplasma gondii and Plasmodium species. Research Group: Meissner Laboratory Location: Lena-Christ-Str. 48, 82152 Planegg-Martinsried Contact: markus.meissner@lmu.de His work investigates the secretory pathway of parasites, vesicular trafficking systems, and essential genes involved in host cell invasion and intracellular development. Toxoplasma gondii serves as a model organism for studying Apicomplexan biology, including nuclear division and CRMP complex functionality. Recent publications highlight the role of Rab GTPases in protein trafficking, chromatin remodeling in Plasmodium, and actin dynamics in parasite motility. Articles span topics such as egress factors, Golgi pathways, and lineage-specific organelle emergence, reflecting a multidisciplinary approach combining molecular biology, cell biology, and evolutionary analysis. The Meissner Lab includes PhD students (Peipei Qin, Yuan Song, Ella Schadt, Vitoria Catschor dos Santos) and postdocs (Dr. Wei Li, Dr. Miriam Rafajlovic). Research is conducted in Lena-Christ-Str. 48, Planegg-Martinsried, with a focus on experimental systems for studying parasite mechanisms.

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Jens S. Andersenمشاهده پروفایل

استاد

University of Southern DenmarkDenmark

Jens S. Andersen is a Professor in the Department of Biochemistry and Molecular Biology at the University of Southern Denmark, where he leads research in Biomedical Mass Spectrometry and Systems Biology. His work is centered on the development and application of quantitative mass spectrometry and microscopy-based proteomics to study human cell biology, particularly the structure and function of organelles such as centrosomes, cilia, autophagosomes, and mitochondria. His research focuses on determining the protein composition and dynamic properties of cellular organelles, the roles of specific protein groups, and their contributions to biological processes and diseases. He investigates cell signaling mediated by post-translational modifications, especially within the DNA damage response, autophagy, and immune systems. His lab, the Jens S. Andersen Lab, is part of the Research Section of Biomedical Mass Spectrometry. The analysis of his recent publications reveals a strong interdisciplinary trend combining proteomics, structural biology, and cell signaling. His work spans cilia biology, RNA metabolism, DNA repair, and cancer mechanisms, with frequent use of advanced techniques like mass spectrometry, CRISPR, and live-cell imaging. The integration of systems biology approaches is evident across his research outputs. Professor, Department of Biochemistry and Molecular Biology, University of Southern Denmark Head of Research, Biomedical Mass Spectrometry and Systems Biology Principal Investigator, Jens S. Andersen Lab ORCID: 0000-0002-6091-140X While no specific scientific awards are mentioned in the provided texts, his extensive publication record in high-impact journals such as Science , Nature Communications , Molecular Cell , and EMBO Journal reflects significant scholarly contributions. He has supervised research projects and collaborated widely across Europe, though specific names of students are not listed. His research is supported by multiple ongoing projects, reflecting sustained funding and academic leadership. The Jens S. Andersen Lab operates at the intersection of proteomics and cell biology, contributing to fundamental understanding of organelle dynamics and disease mechanisms. The lab's work is highly collaborative, involving partnerships with groups in structural biology, RNA research, and cancer biology.

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Shahid Siddiqueمشاهده پروفایل

دانشیار

University of California, DavisUnited States

Shahid Siddique is an Associate Professor in the Department of Entomology and Nematology at the University of California, Davis. His research focuses on understanding molecular and applied aspects of plant-parasitic nematode interactions with host plants. He aims to develop sustainable strategies to mitigate nematode-induced crop losses through genetic, biochemical, and biotechnological approaches. His lab is particularly interested in host resistance mechanisms, nematode effector proteins, and biocontrol solutions. Education: MSc, Bahauddin Zakariya University, Multan, Pakistan PhD, University of Natural Resources and Life Sciences, Vienna, Austria Habilitation, University of Bonn, Germany Research Interests: Siddique’s work bridges basic and applied research, including cell surface signaling in plant-parasitic nematode interactions, functional characterization of secretory proteins, molecular diagnostics for nematodes, and biocontrol strategies. Current projects explore recombination hotspots in nematode genomes, CRISPR-based resistance engineering, and redox signaling mechanisms. Teaching: General Plant Nematology (NEM100) in Spring 2020 Labs/Teams: The Siddique Lab focuses on translating molecular discoveries into practical pest management solutions. Collaborations involve genomic analysis, proteomics, and field trials to address global agricultural challenges.

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Jude M. Phillipمشاهده پروفایل

استادیار

Johns Hopkins UniversityUnited States

Aging
Mechanobiology
Cancer Biology
+۵ مورد دیگر

Jude M. Phillip, PhD, is an Assistant Professor in the Departments of Biomedical Engineering and Chemical and Biomolecular Engineering at Johns Hopkins University. His research integrates engineering principles with aging and cancer biology to develop cell-based biomarkers and mechanistic insights into age-related diseases. He leads the Phillip tiME Lab, which focuses on aging dynamics, tumor microenvironment interactions, and translational technologies. Education : PhD, Chemical and Biomolecular Engineering, Johns Hopkins University, 2015 Postdoctoral Research, Melnick/Cerchietti Labs, Weill Cornell Medicine, 2016-2020 B.Eng, Chemical Engineering, City College of New York, 2010 Research Interests : Dr. Phillip’s work spans aging mechanisms, cancer biology, and mechanobiology. Key areas include: Cell-based biomarkers for aging and disease Scale-dependent aging pathways Lymphoma tumor-immune microenvironment (tiME) Single-cell profiling of senescence subtypes ECM mechanoregulation of stem cell fate His lab employs longitudinal cell profiling, data science, and clinical measures to bridge biological aging research with translational medicine. Recent Highlights : 2025: NIH R35 MIRA Award for lymphoma microenvironment research 2024: Johns Hopkins Catalyst Award for aging biomarker studies 2023: AFAR-Glenn Foundation Award for senescence subtype classification Lab & Collaborations : The Phillip Lab collaborates with the Institute for NanoBioTechnology and maintains a living patient-derived tumor biorepository for lymphoma studies. Current projects include ovarian aging organoid models and immune-mechanical interactions in cancer progression.

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Xia Gaoمشاهده پروفایل

استادیار

Baylor College of MedicineUnited States

Nutrition
Metabolism
Cancer Metabolism
+۷ مورد دیگر

Xia Gao is an Assistant Professor in the Department of Pediatrics-Nutrition and the Department of Molecular and Cellular Biology at Baylor College of Medicine. She leads the Gao Lab, based at the USDA/ARS Children's Nutrition Research Center in Houston, Texas, where she investigates the role of nutrition and metabolism in diseases such as cancer and obesity. Her research focuses on amino acid metabolism, particularly the impact of dietary methionine and serine restriction on cancer progression and therapy efficacy. She employs in vivo mouse models and in vitro systems combined with metabolomics, molecular biology, and immunology techniques. The most recent publications from her lab reveal a strong trend in cancer metabolism, especially in prostate and liver cancers, with a focus on dietary interventions, metabolic reprogramming, and immune cell metabolism. Her work bridges nutritional science and precision oncology, aiming to develop effective dietary therapies. Dietary methionine influences therapy in mouse cancer models and alters human metabolism (Nature, 2019) HNF4α regulates sulfur amino acid metabolism and confers sensitivity to methionine restriction in liver cancer (Nature Communications, 2020) Targeting glutamine metabolism in therapy-resistant prostate cancer (Oncogene, 2022) Dr. Gao is supported by competitive grants, including a CPRIT award (RP210056) on dietary methionine restriction to enhance chemotherapy, and an NIH/NCI R00 grant on methionine metabolism in cancer. These grants underscore her role as an independent investigator with significant research funding. The Gao Lab is part of the USDA/ARS Children's Nutrition Research Center, a premier research facility equipped with advanced laboratories, a metabolic kitchen, and interdisciplinary teams focused on child and adult nutrition and disease prevention.

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Markus Riesslandمشاهده پروفایل

استادیار

Stony Brook UniversityUnited States

Markus Riessland is an Assistant Professor at Stony Brook University’s Renaissance School of Medicine, part of the Empire Innovation Program focused on the Aging Brain. He holds a PhD from the University of Cologne, Germany, specializing in molecular biology, neuroscience, and neurodegenerative diseases. His research centers on cellular senescence in neurons, particularly post-mitotic dopaminergic neurons linked to Parkinson’s disease. He discovered that these neurons can undergo senescence, a process typically absent in non-dividing cells, which has implications for aging and neurodegeneration. Dr. Riessland’s lab employs stem cell models, mouse studies, and advanced sequencing techniques (TRAP-seq, RNA-seq) to investigate senescence mechanisms, identify genetic modifiers influencing neuronal vulnerability, and explore therapies to counteract senescence-driven pathology. His work bridges molecular biology and clinical implications, emphasizing translational approaches for age-related diseases. Notable achievements include an F1000 Exceptional Rating for his 2017 Cell Stem Cell paper and an AJHG Editor’s Corner Highlight for his ribosome profiling study. His research has led to insights on SATB1’s role in senescence, lipid-driven senescence in dopaminergic neurons, and midbrain inflammation in Parkinson’s. Collaborative efforts span international projects on SMA and neuroprotective modifiers like Neurocalcin Delta. While no students are listed here, his work impacts therapeutic development in neurodegenerative diseases through senolytic strategies and genetic interventions. Education: PhD in Molecular Biology from University of Cologne, Germany. Awards: F1000 Exceptional Rating (2017), AJHG Editor’s Corner Highlight (2017). Labs/Teams: Leads research on neuronal senescence mechanisms and therapeutic targets, integrating stem cell biology and systems biology approaches.

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Karin Schumacherمشاهده پروفایل

استاد

Heidelberg UniversityGermany

Prof. Dr. Karin Schumacher is a Professor of Plant Developmental Biology at Heidelberg University and currently serves as Vice-Rector for Quality Development and Sustainability. Her research focuses on plant cell biology, particularly vacuole dynamics, ion homeostasis, and membrane trafficking in Arabidopsis. She leads the Cell Biology Research Group at the Centre for Organismal Studies (COS) and has held leadership roles such as Dean of the Faculty of Biosciences. Her work integrates computational modeling with experimental approaches to study plant growth and stress responses. Dr. Schumacher's academic career includes a Doctorate from the University of Cologne and a Habilitation from the University of Tübingen. She has held professorial positions since 2007 and contributed to advancements in understanding plant membrane systems, including V-ATPase function and calcium signaling. Her research publications emphasize vacuolar ion transport, autophagy mechanisms, and plant stress physiology. Her administrative roles include enhancing early career researcher support and promoting sustainability in university operations. She is an active member of scientific societies like the German Botanical Society and serves on editorial boards such as Plant Cell . Her interdisciplinary work bridges cell biology, molecular genetics, and systems-level plant physiology.

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Matthias Feigeمشاهده پروفایل

دانشیار

Technical University of MunichGermany

Matthias Feige is an Associate Professor of Cellular Protein Biochemistry at the Technical University of Munich (TUM). He leads the Focus Group for Cellular Protein Biochemistry, previously serving as a Rudolf Mößbauer Tenure Track Assistant Professor. His research focuses on understanding cellular proteome integrity, particularly in the secretory pathway, combining protein biochemistry and cell biology. Key interests include protein folding, quality control mechanisms, and their biomedical applications. Education & Career: PhD in Biochemistry (2009), TUM under Johannes Buchner Postdoctoral Fellowship at St. Jude Children’s Research Hospital (Memphis, USA) with Linda Hendershot Head of the Cellular Protein Biochemistry Lab at TUM since 2015 Research Interests: Feige’s work explores molecular mechanisms governing protein biogenesis, secretory pathway proteins, and their roles in immunity. His interdisciplinary approach targets fundamental biology and translational applications like protein engineering and therapy development. Scientific Contributions: His publications highlight advancements in cytokine assembly, ER quality control, and protein aggregation mechanisms. Notable recent work includes studies on KDELR3 signaling, helminth immune modulation, and engineered cytokines. Awards & Recognition: Leopoldina Fellowship (2011–2014) Fellow of the Daimler and Benz Foundation (2016) Rainer Rudolph Award (2012) Multiple honors from TUM and international institutions Labs & Teams: He directs a lab investigating protein biogenesis and proteostasis. Collaborations span biochemistry, immunology, and structural biology, with a focus on translational research.

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Hal Alperمشاهده پروفایل

استاد

University of Texas at AustinUnited States

Hal Alper is a Professor and holds the Cockrell Family Regents Chair in Engineering at the University of Texas at Austin's Department of Chemical Engineering. His research lab focuses on rewiring cellular metabolism for biomanufacturing applications, including biofuels, pharmaceuticals, and sustainable materials, using synthetic biology, directed evolution, and pathway engineering. Education: Postdoctoral Research Associate, Whitehead Institute for Biomedical Research (2006-2008) Postdoctoral Research Associate, Shire Human Genetic Therapies (2007-2008) Ph.D., Chemical Engineering, Massachusetts Institute of Technology (2006) B.S., Chemical Engineering, University of Maryland, College Park (2002) Research Focus: The Alper Lab specializes in metabolic and cellular engineering to address global challenges in sustainability and health. Core methodologies include synthetic biology tool development, high-throughput screening platforms (e.g., biosensor-in-microdroplet systems), and evolutionary engineering of yeast strains like Saccharomyces cerevisiae and Yarrowia lipolytica . Key application areas are biofuels, biochemicals, polymer precursors, and pharmaceuticals. Publication Trends: Recent work emphasizes machine learning-assisted enzyme engineering, microbial consortia design, and advanced screening techniques for metabolic phenotypes. A consistent theme across publications is the optimization of yeast hosts for efficient bioproduction through promoter engineering, transporter modification, and evolutionary strategies. Awards & Honors: Fellow, American Association for the Advancement of Science (2024) Andreas Acrivos Award (AIChE, 2023) Fellow, National Academy of Inventors (2019) O'Donnell Award in Engineering (2019) AIChE Colburn Award (2018) Society for Industrial Microbiology Young Investigator (2015) Dreyfus Teacher-Scholar (2014) Regents’ Outstanding Teaching Award (2012) ONR Young Investigator (2011) Lab Leadership: Directs the Laboratory for Cellular and Metabolic Engineering, fostering interdisciplinary work in synthetic biology and bioprocess development. The lab prioritizes inclusivity and collaborative research, with projects spanning genetic toolkit development, metabolic flux analysis, and scalable biomanufacturing platforms.

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Harald Pichlerمشاهده پروفایل

دانشیار

Graz University of TechnologyAustria

Harald Pichler is an Associate Professor and Team Leader at the Institute of Biotechnology (IMBT) at Graz University of Technology. His research focuses on membrane biology, enzyme engineering, and industrial biotechnology using yeast systems like Pichia pastoris . Key projects include engineering microbial membranes for protein secretion, optimizing biocatalysts for terpenoid synthesis, and studying lipid interactions with membrane proteins. Collaborations with companies like DSM and LONZA highlight industrial applications of his work. Research interests span microbial membrane modifications, sterol biosynthesis, and metabolic engineering for producing valuable metabolites. Major contributions include developing yeast strains for high-throughput screening of terpenoids and engineering hydratases for biocatalytic applications. His team also explores protein secretion pathways and membrane protein expression in yeasts, with patent filings for key genetic targets. Current projects involve lipid raft dynamics, SARS-CoV-2 spike protein interactions with membranes, and low-cost cell culture media alternatives. Collaborations with academic partners like the University of Geneva and Wageningen University emphasize interdisciplinary approaches. Publications frequently address membrane biophysics, enzyme mechanisms, and yeast strain engineering, reflecting a blend of fundamental and applied research.

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Rebecca Taylorمشاهده پروفایل

مدرس

University of East AngliaUnited Kingdom

Rebecca Taylor is a Lecturer in Biomedicine at the School of Biological Sciences, University of East Anglia (UEA). She leads an active research group focused on biological resilience, cellular stress responses, and the molecular mechanisms linking ageing and homeostasis. She is currently accepting PhD students, indicating ongoing academic mentorship and research supervision. Research Interests: Dr. Taylor's research centers on understanding how cells and organisms maintain homeostasis under stress. Her lab investigates the secretory pathway as a central hub for stress response coordination, with a particular interest in how ageing disrupts these pathways. Key aims include identifying novel stress resistance mechanisms, understanding systemic coordination of resilience, and exploring how modulating stress pathways can influence ageing and age-related diseases. Publication Trends: Her recent work, published in journals like Nature Aging , Frontiers in Aging , and Nature Chemical Biology , shows a strong focus on model organisms (especially C. elegans ), unfolded protein response (UPR), TGF-β signaling, and the intersection of sensory perception and lifespan regulation. The research integrates molecular biology, genetics, and systems-level approaches to uncover conserved mechanisms of ageing and resilience. Scientific Recognition: While specific awards are not listed, her work has garnered significant attention, with over 3500 citations (Scopus) and an h-index of 11. Her research has been highlighted on social media platforms (X, Facebook), picked up by news outlets, and blogged about, indicating broad academic and public engagement. Mentorship and Research Output: Dr. Taylor actively supervises research, as evidenced by her co-authorship with junior researchers and her openness to PhD students. Her lab produces a steady stream of high-quality publications, including original research articles and commentaries, contributing to key discussions in ageing and stress biology. She collaborates with an international network of scientists, as shown by her co-authorship on conference reports and multi-institutional studies. Laboratory and Collaboration: The Taylor Lab operates within the School of Biological Sciences at UEA, focusing on experimental models to dissect stress response pathways. Her collaborations span multiple institutions and countries, reflecting an integrated approach to studying organismal proteostasis and ageing. The lab utilizes genetic, biochemical, and behavioral assays to explore fundamental questions in biomedicine.

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